pyrimethamine has been researched along with Neoplasm Metastasis in 11 studies
Maloprim: contains above 2 cpds
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antimalarial drug Pyrimethamine has been suggested to exert an antitumor activity by inducing apoptotic cell death in cancer cells, including metastatic melanoma cells." | 7.83 | New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study. ( Alberton, M; Buoncervello, M; Cerbelli, B; d'Amati, G; Gabriele, L; Gambardella, L; Giammarioli, AM; Golding, BT; Griffin, RJ; Macchia, D; Malorni, W; Spada, M; Tommasino, C, 2016) |
| "Osimertinib is a tyrosine kinase approved and effective in treating lung adenocarcinomas that have one of several common activating mutations in epidermal growth factor receptor." | 6.72 | OPALS: A New Osimertinib Adjunctive Treatment of Lung Adenocarcinoma or Glioblastoma Using Five Repurposed Drugs. ( Halatsch, ME; Kast, RE; Rosell, R, 2021) |
| "The antimalarial drug Pyrimethamine has been suggested to exert an antitumor activity by inducing apoptotic cell death in cancer cells, including metastatic melanoma cells." | 3.83 | New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study. ( Alberton, M; Buoncervello, M; Cerbelli, B; d'Amati, G; Gabriele, L; Gambardella, L; Giammarioli, AM; Golding, BT; Griffin, RJ; Macchia, D; Malorni, W; Spada, M; Tommasino, C, 2016) |
| "Osimertinib is a tyrosine kinase approved and effective in treating lung adenocarcinomas that have one of several common activating mutations in epidermal growth factor receptor." | 2.72 | OPALS: A New Osimertinib Adjunctive Treatment of Lung Adenocarcinoma or Glioblastoma Using Five Repurposed Drugs. ( Halatsch, ME; Kast, RE; Rosell, R, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Kast, RE | 1 |
| Halatsch, ME | 1 |
| Rosell, R | 1 |
| Liu, H | 1 |
| Qin, Y | 1 |
| Zhai, D | 1 |
| Zhang, Q | 1 |
| Gu, J | 1 |
| Tang, Y | 1 |
| Yang, J | 1 |
| Li, K | 1 |
| Yang, L | 1 |
| Chen, S | 1 |
| Zhong, W | 1 |
| Meng, J | 1 |
| Liu, Y | 1 |
| Sun, T | 1 |
| Yang, C | 1 |
| Tommasino, C | 1 |
| Gambardella, L | 2 |
| Buoncervello, M | 1 |
| Griffin, RJ | 1 |
| Golding, BT | 1 |
| Alberton, M | 1 |
| Macchia, D | 1 |
| Spada, M | 2 |
| Cerbelli, B | 1 |
| d'Amati, G | 1 |
| Malorni, W | 2 |
| Gabriele, L | 1 |
| Giammarioli, AM | 2 |
| Maselli, A | 1 |
| Casagrande, A | 1 |
| Gallina, A | 1 |
| Giovannetti, A | 1 |
| Proietti, E | 1 |
| Pierdominici, M | 1 |
| TENHUNEN, A | 1 |
| Lynch, G | 1 |
| Currie, V | 1 |
| Kemeny, N | 1 |
| Douglas, ID | 1 |
| Gordon, MY | 1 |
| Prentice, GH | 1 |
| Hill, BT | 1 |
| Price, LA | 1 |
| Hindmarsh, JR | 1 |
| Hall, RR | 1 |
| Kulatilake, AE | 1 |
| Osieka, R | 1 |
| Schmidt, CG | 1 |
| Blackledge, G | 1 |
| Verweij, J | 1 |
| Fuchs, R | 1 |
| Keizer, HJ | 1 |
| Somers, R | 1 |
| Rankin, E | 1 |
| Kerbrat, P | 1 |
| van Oosterom, A | 1 |
| Sylvester, R | 1 |
| Thomas, D | 1 |
1 review available for pyrimethamine and Neoplasm Metastasis
| Article | Year |
|---|---|
OPALS: A New Osimertinib Adjunctive Treatment of Lung Adenocarcinoma or Glioblastoma Using Five Repurposed Drugs.
Topics: Acrylamides; Adenocarcinoma of Lung; Aniline Compounds; Animals; Azithromycin; Carcinoma, Non-Small- | 2021 |
10 other studies available for pyrimethamine and Neoplasm Metastasis
| Article | Year |
|---|---|
Antimalarial Drug Pyrimethamine Plays a Dual Role in Antitumor Proliferation and Metastasis through Targeting DHFR and TP.
Topics: Antimalarials; Antineoplastic Agents; Cell Proliferation; Humans; Lung Neoplasms; Methotrexate; Mole | 2019 |
New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study.
Topics: Animals; Antineoplastic Agents; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Sur | 2016 |
Pyrimethamine induces apoptosis of melanoma cells via a caspase and cathepsin double-edged mechanism.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cathepsins; Cell Proliferation; Female; Folic A | 2008 |
GLANDULAR TOXOPLASMOSIS. OCCURRENCE OF THE DISEASE IN FINLAND.
Topics: Biopsy; Diagnosis, Differential; Epidemiology; Female; Finland; Hodgkin Disease; Humans; Lymph Node | 1964 |
Phase II evaluation of metoprine with leucovorin rescue in patients with advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Drug Therapy, Combination; F | 1981 |
Protection with single-dose folinic acid against bone-marrow depression by long-acting diaminopyrimidines.
Topics: Adenocarcinoma; Administration, Oral; Antineoplastic Agents; Bone Marrow; Depression, Chemical; Huma | 1977 |
Renal cell carcinoma: a preliminary clinical trial of methodichlorophen (D.D.M.P.).
Topics: Adenocarcinoma; Aged; Anorexia; Attention; Female; Headache; Humans; Kidney Neoplasms; Male; Middle | 1979 |
[Diagnosis and therapy of neoplastic meningosis].
Topics: Acute Disease; Central Nervous System Diseases; Cytarabine; Humans; Injections, Spinal; Leukemia; Me | 1975 |
A phase II study of M-azido-pyrimethamine ethane sulphonate (MZPES) in advanced, recurrent soft tissue sarcoma. An EORTC Soft Tissue and Bone Sarcoma Group Study.
Topics: Adult; Aged; Azides; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Pyrime | 1989 |
Treating the nervous system in acute leukemia.
Topics: Humans; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Nervous System Diseas | 1972 |