pyrimethamine has been researched along with Leukemia, Lymphocytic in 13 studies
Maloprim: contains above 2 cpds
| Excerpt | Relevance | Reference |
|---|---|---|
| "By this procedure a subline of Burkitt's lymphoma cells (RAJI) was made 290-fold resistant (RAJI/MTX-R), T-cell leukemia cells (CCRF-CEM) were obtained 210-fold resistant (CEM/MTX-R), and 3 MTX-resistant human osteosarcoma lines were selected: TE-85/MTX-R (19-fold resistant; relative to wild-type); MG-63/MTX-R (8-fold resistant); and SAOS-2/MTX-R (200-fold resistant)." | 5.27 | Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate. ( Diddens, H; Jackson, RC; Niethammer, D, 1983) |
| "Oral pyrimethamine and CCNU were used for their potential activity as prophylactics against meningeal leukemia." | 2.64 | Combination chemotherapy of adult acute lymphocytic leukemia. ( Smyth, AC; Wiernik, PH, 1976) |
| "By this procedure a subline of Burkitt's lymphoma cells (RAJI) was made 290-fold resistant (RAJI/MTX-R), T-cell leukemia cells (CCRF-CEM) were obtained 210-fold resistant (CEM/MTX-R), and 3 MTX-resistant human osteosarcoma lines were selected: TE-85/MTX-R (19-fold resistant; relative to wild-type); MG-63/MTX-R (8-fold resistant); and SAOS-2/MTX-R (200-fold resistant)." | 1.27 | Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate. ( Diddens, H; Jackson, RC; Niethammer, D, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diddens, H | 1 |
| Niethammer, D | 1 |
| Jackson, RC | 1 |
| Wiernik, PH | 2 |
| Devivo, DC | 1 |
| Malas, D | 1 |
| Nelson, JS | 1 |
| Land, VJ | 1 |
| Armata, J | 2 |
| Cyklis, R | 2 |
| Borkowski, W | 1 |
| Smyth, AC | 1 |
| Hill, BT | 2 |
| Price, LA | 3 |
| Harrison, SI | 2 |
| Goldie, JH | 3 |
| Carey, RM | 1 |
| Kimball, AC | 1 |
| Armstrong, D | 1 |
| Lieberman, PH | 1 |
| Furness, ME | 1 |
| Roth, JA | 1 |
| Siegel, SE | 1 |
| Levine, AS | 1 |
| Berard, CW | 1 |
| Kirby, HB | 1 |
| Kenamore, B | 1 |
| Guckian, JC | 1 |
1 trial available for pyrimethamine and Leukemia, Lymphocytic
| Article | Year |
|---|---|
Combination chemotherapy of adult acute lymphocytic leukemia.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dexamethasone; Drug Administration Schedule; Drug Thera | 1976 |
12 other studies available for pyrimethamine and Leukemia, Lymphocytic
| Article | Year |
|---|---|
Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
Topics: Antineoplastic Agents; Biological Transport; Burkitt Lymphoma; Cell Line; Drug Resistance; Folic Aci | 1983 |
The therapy of acute leukemia in the adult: a progress report.
Topics: Acute Disease; Adult; Antineoplastic Agents; Azacitidine; Blood Transfusion; Cytarabine; Daunorubici | 1976 |
Leukoencephalopathy in childhood leukemia.
Topics: Adolescent; Cerebral Cortex; Gliosis; Humans; Leukemia, Lymphoid; Leukoencephalopathy, Progressive M | 1977 |
Pyrimethamine in prevention of relapses of meningeal leukemia: report of two cases.
Topics: Central Nervous System; Child; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; M | 1978 |
[Daraprim in the prevention of recurrences of meningeal involvement in 2 children with acute leukemia followed up for about 8 years].
Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; Meningeal Neop | 1978 |
Studies on the transport and distribution of diaminopyrimidines in L5178Y lymphoblasts in cell culture.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Cell Line; Chlorobenzenes; Diamines; Kinetics; | 1975 |
Impaired responsiveness to folinic acid protection in methotrexate-resistant L5178Y cells.
Topics: Biological Transport; Cell Line; Cell Survival; Drug Resistance; Leucovorin; Leukemia, Lymphoid; Lym | 1975 |
Treating the nervous system in acute leukemia.
Topics: Humans; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Nervous System Diseas | 1972 |
Toxoplasmosis. Clinical experiences in a cancer hospital.
Topics: Adolescent; Adult; Aged; Child; Complement Fixation Tests; Diagnosis, Differential; Female; Hodgkin | 1973 |
Comparison of the effects of methotrexate and pyrimethamine on L5178Y lymphoblasts in cell culture.
Topics: Adenosine; Animals; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Centrifugation; Dose-R | 1973 |
Fatal recurrent toxoplasmosis in a patient initially infected via a leukocyte transfusion.
Topics: Autopsy; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Leukocytes; Pyrimethamine; Recurrence | 1971 |
Pneumocystis carinii pneumonia treated with pyrimethamine and sulfadiazine.
Topics: Adult; Follow-Up Studies; Humans; Leukemia, Lymphoid; Lupus Erythematosus, Systemic; Lymphoma, Non-H | 1971 |