pyrimethamine has been researched along with Jaundice in 4 studies
Maloprim: contains above 2 cpds
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is recommended that children aged 3 months to five years of age living in areas of seasonal transmission in the sub-Sahel should receive Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ) during the malaria transmission season." | 9.22 | Safety of Seasonal Malaria Chemoprevention (SMC) with Sulfadoxine-Pyrimethamine plus Amodiaquine when Delivered to Children under 10 Years of Age by District Health Services in Senegal: Results from a Stepped-Wedge Cluster Randomized Trial. ( Ba, EH; Cairns, M; Cissé, B; Fall, FB; Faye, B; Gaye, O; Gomis, JF; Greenwood, BM; Kouevijdin, E; Milligan, PJ; Molez, JF; NDiaye, JL; Ndour, CT; Niane, FK; Rogier, C; Sokhna, C; Trape, JF, 2016) |
| "It is recommended that children aged 3 months to five years of age living in areas of seasonal transmission in the sub-Sahel should receive Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine plus amodiaquine (SPAQ) during the malaria transmission season." | 5.22 | Safety of Seasonal Malaria Chemoprevention (SMC) with Sulfadoxine-Pyrimethamine plus Amodiaquine when Delivered to Children under 10 Years of Age by District Health Services in Senegal: Results from a Stepped-Wedge Cluster Randomized Trial. ( Ba, EH; Cairns, M; Cissé, B; Fall, FB; Faye, B; Gaye, O; Gomis, JF; Greenwood, BM; Kouevijdin, E; Milligan, PJ; Molez, JF; NDiaye, JL; Ndour, CT; Niane, FK; Rogier, C; Sokhna, C; Trape, JF, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| NDiaye, JL | 1 |
| Cissé, B | 1 |
| Ba, EH | 1 |
| Gomis, JF | 1 |
| Ndour, CT | 1 |
| Molez, JF | 1 |
| Fall, FB | 1 |
| Sokhna, C | 1 |
| Faye, B | 1 |
| Kouevijdin, E | 1 |
| Niane, FK | 1 |
| Cairns, M | 1 |
| Trape, JF | 1 |
| Rogier, C | 1 |
| Gaye, O | 1 |
| Greenwood, BM | 1 |
| Milligan, PJ | 1 |
| Abro, AH | 1 |
| Ustadi, AM | 1 |
| Abro, HA | 1 |
| Abdou, AS | 1 |
| Younis, NJ | 1 |
| Akaila, SI | 1 |
| Olsen, VV | 1 |
| Loft, S | 1 |
| Christensen, KD | 1 |
| Hof, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Public Health Impact and Cost Effectiveness of Seasonal Intermittent Preventive Treatment in Children in Senegal[NCT00712374] | Phase 4 | 100,000 participants (Anticipated) | Interventional | 2008-09-30 | Enrolling by invitation | ||
| A Phase IIIB Comparative Trial of Seasonal Vaccination With the Malaria Vaccine RTS,S/AS01, Seasonal Malaria Chemoprevention and of the Two Interventions Combined[NCT03143218] | Phase 3 | 5,920 participants (Actual) | Interventional | 2017-04-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Passive surveillance to detect episode of fever (temperature > 37.5 C), or a history of fever within the past 48 hours, that is severe enough to require treatment at a health centre and which is accompanied by a positive blood film with a parasite density of 5,000 per µl or more (NCT03143218)
Timeframe: Passive surveillance of clinical episodes of malaria within the study area starting from the date of the first dose of study vaccines (April/May 2017) until 31st March 2020- a total of 36 months.
| Intervention | No. of events/1000 person years at risk (Number) |
|---|---|
| SMC With SP+AQ | 304.8 |
| RTS,S/AS01 | 278.2 |
| RTS,S/AS01 PLUS SMC With SP+AQ | 113.3 |
1 trial available for pyrimethamine and Jaundice
3 other studies available for pyrimethamine and Jaundice
| Article | Year |
|---|---|
Jaundice with hepatic dysfunction in P. falciparum malaria.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Animals; Antimalarials; Female; Humans; Jaundice; Liv | 2009 |
Serious reactions during malaria prophylaxis with pyrimethamine-sulfadoxine.
Topics: Aged; Agranulocytosis; Antimalarials; Drug Combinations; Female; Humans; Jaundice; Malaria; Male; Mi | 1982 |
[Toxoplasma gondii. Infection and its prevention].
Topics: Animals; Antibody Formation; Cats; Chorioretinitis; Chronic Disease; Complement Fixation Tests; Dise | 1978 |