pyrimethamine has been researched along with Hemorrhagic Shock in 6 studies
Maloprim: contains above 2 cpds
| Excerpt | Relevance | Reference |
|---|---|---|
| "An increase in endogenous central histamine concentration after inhibition of histamine N-methyltransferase (HNMT) activity reverses critical hypotension and improves the survival of rats in haemorrhagic shock." | 7.72 | Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats. ( Jochem, J, 2004) |
| "The study was undertaken to examine the involvement of the renin-angiotensin system in the reversal by endogenous central histamine of critical haemorrhagic hypotension in anaesthetised Wistar rats." | 7.72 | Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentrations, after loading with histamine precursor L-histidine or inhibition of histamine N-methyltransferase (HNMT) activity, produces the reversal of critical hypotension with improvement in survival of haemorrhage-shocked rats." | 7.72 | Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentration after inhibition of histamine N-methyltransferase (HNMT) activity reverses critical hypotension and improves the survival of rats in haemorrhagic shock." | 3.72 | Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats. ( Jochem, J, 2004) |
| "The study was undertaken to examine the involvement of the renin-angiotensin system in the reversal by endogenous central histamine of critical haemorrhagic hypotension in anaesthetised Wistar rats." | 3.72 | Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentrations, after loading with histamine precursor L-histidine or inhibition of histamine N-methyltransferase (HNMT) activity, produces the reversal of critical hypotension with improvement in survival of haemorrhage-shocked rats." | 3.72 | Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "The increase in central histamine concentrations after inhibition of histamine N-methyltransferase (HNMT) activity is associated with the reversal of critical haemorrhagic hypotension, therefore the present study examines cardiac and regional haemodynamic effects of HNMT inhibitor metoprine in haemorrhage-shocked rats." | 3.72 | Cardiac and regional haemodynamic effects of histamine N-methyltransferase inhibitor metoprine in haemorrhage-shocked rats. ( Jochem, J, 2004) |
| "A case is presented of a mechanical cardiac valve dysfunction occurring in a 19-year-old Nigerian 7 years after valve surgery and presenting with cardiac failure, supraventricular tachycardia and later, cardiogenic shock but initially masquerading as generalised bleeding probably from Warfarin-drug interaction." | 3.68 | Prosthetic valve dysfunction in a Nigerian. ( Ajuyah, CO; Obasohan, AO; Ukoh, V, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jochem, J | 5 |
| Irman-Florjanc, T | 1 |
| Zwirska-Korczala, K | 1 |
| Obasohan, AO | 1 |
| Ukoh, V | 1 |
| Ajuyah, CO | 1 |
6 other studies available for pyrimethamine and Hemorrhagic Shock
| Article | Year |
|---|---|
Involvement of the sympathetic nervous system in the reversal of critical haemorrhagic hypotension by endogenous central histamine in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine Derivatives; Blood Pres | 2004 |
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain Chemistry; C | 2004 |
Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain Chemistry; Disease Models, Animal; Heart Rate | 2004 |
Cardiac and regional haemodynamic effects of histamine N-methyltransferase inhibitor metoprine in haemorrhage-shocked rats.
Topics: Animals; Blood Pressure; Cardiovascular System; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino | 2004 |
The role of peripherally acting histamine in metoprine-induced reversal of haemorrhagic hypotension in rats--skeletal muscle microcirculatory studies.
Topics: Animals; Hemorrhage; Histamine; Hypotension; Male; Microcirculation; Muscle, Skeletal; Pyrimethamine | 2005 |
Prosthetic valve dysfunction in a Nigerian.
Topics: Adult; Antimalarials; Drug Combinations; Drug Interactions; Fatal Outcome; Heart Failure; Heart Valv | 1993 |