pyrimethamine has been researched along with Hematologic Diseases in 7 studies
Maloprim: contains above 2 cpds
Hematologic Diseases: Disorders of the blood and blood forming tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulphadoxine-Pyrimethamine (SP) is still the only recommended antimalarial for use in intermittent preventive treatment of malaria during pregnancy (IPTp) in some malaria endemic countries including Ghana." | 7.81 | Glucose-6-Phosphate Dehydrogenase Deficiency and Haemoglobin Drop after Sulphadoxine-Pyrimethamine Use for Intermittent Preventive Treatment of Malaria during Pregnancy in Ghana - A Cohort Study. ( Amu, A; Anyorigiya, T; Asante, KP; Awini, E; Bart-Plange, C; Dosoo, D; Gyapong, M; Hodgson, A; Jakpa, G; Mahama, E; Oduro, AR; Ofei, E; Owusu, R; Owusu-Agyei, S; Segbaya, S, 2015) |
| "There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis." | 7.67 | Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985) |
| "Pyrimethamine, a folate antagonist similar to methrotrexate without known hepatotoxcity in man, was administer orally, once a week, to seven patients with severe, long-standing psoriasis." | 7.65 | Treatment of servere psoriasis with pyrimethamine. ( Aeling, JL; Andreozzi, RJ; DiBella, NJ; Nuss, DD, 1977) |
| "Sulphadoxine-Pyrimethamine (SP) is still the only recommended antimalarial for use in intermittent preventive treatment of malaria during pregnancy (IPTp) in some malaria endemic countries including Ghana." | 3.81 | Glucose-6-Phosphate Dehydrogenase Deficiency and Haemoglobin Drop after Sulphadoxine-Pyrimethamine Use for Intermittent Preventive Treatment of Malaria during Pregnancy in Ghana - A Cohort Study. ( Amu, A; Anyorigiya, T; Asante, KP; Awini, E; Bart-Plange, C; Dosoo, D; Gyapong, M; Hodgson, A; Jakpa, G; Mahama, E; Oduro, AR; Ofei, E; Owusu, R; Owusu-Agyei, S; Segbaya, S, 2015) |
| "There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis." | 3.67 | Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985) |
| "Pyrimethamine, a folate antagonist similar to methrotrexate without known hepatotoxcity in man, was administer orally, once a week, to seven patients with severe, long-standing psoriasis." | 3.65 | Treatment of servere psoriasis with pyrimethamine. ( Aeling, JL; Andreozzi, RJ; DiBella, NJ; Nuss, DD, 1977) |
| " Dosage must be adjusted to the results of blood counts." | 2.38 | [Usefulness of folinic acid in cytopenia induced by antiparasitic drugs in AIDS patients]. ( Leport, C; Niyongabo, T; Vildé, JL, 1991) |
| " Dosage data indicated that fatalities had taken higher doses and continued prophylaxis after onset of symptoms." | 1.28 | Serious adverse drug reactions to pyrimethamine-sulphadoxine, pyrimethamine-dapsone and to amodiaquine in Britain. ( Phillips-Howard, PA; West, LJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Phillips-Howard, PA | 1 |
| West, LJ | 1 |
| Cook, IF | 1 |
| Kish, MY | 1 |
| Owusu, R | 1 |
| Asante, KP | 1 |
| Mahama, E | 1 |
| Awini, E | 1 |
| Anyorigiya, T | 1 |
| Dosoo, D | 1 |
| Amu, A | 1 |
| Jakpa, G | 1 |
| Ofei, E | 1 |
| Segbaya, S | 1 |
| Oduro, AR | 1 |
| Gyapong, M | 1 |
| Hodgson, A | 1 |
| Bart-Plange, C | 1 |
| Owusu-Agyei, S | 1 |
| Hansen, M | 1 |
| Lau, ME | 1 |
| Hansen, HH | 1 |
| DiBella, NJ | 1 |
| Nuss, DD | 1 |
| Aeling, JL | 1 |
| Andreozzi, RJ | 1 |
| Petter, C | 1 |
| Bourbon, J | 1 |
| Niyongabo, T | 1 |
| Leport, C | 1 |
| Vildé, JL | 1 |
1 review available for pyrimethamine and Hematologic Diseases
| Article | Year |
|---|---|
[Usefulness of folinic acid in cytopenia induced by antiparasitic drugs in AIDS patients].
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Folic Acid; Hematologic Diseases; Hum | 1991 |
6 other studies available for pyrimethamine and Hematologic Diseases
| Article | Year |
|---|---|
Serious adverse drug reactions to pyrimethamine-sulphadoxine, pyrimethamine-dapsone and to amodiaquine in Britain.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Chemical and Drug Induced Liver Injury; Child; Child, | 1990 |
Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine.
Topics: Adolescent; Adult; Age Factors; Antimalarials; Child; Child, Preschool; Dapsone; Drug Combinations; | 1985 |
Glucose-6-Phosphate Dehydrogenase Deficiency and Haemoglobin Drop after Sulphadoxine-Pyrimethamine Use for Intermittent Preventive Treatment of Malaria during Pregnancy in Ghana - A Cohort Study.
Topics: Adult; Antimalarials; Cohort Studies; Drug Combinations; Female; Ghana; Glucosephosphate Dehydrogena | 2015 |
Unpredictable hematologic toxicity of weekly ddmp.
Topics: Antineoplastic Agents; Drug Administration Schedule; Drug Therapy, Combination; Folic Acid; Hematolo | 1978 |
Treatment of servere psoriasis with pyrimethamine.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Gastrointestinal Diseases; Hematologic Diseas | 1977 |
Foetal red cell macrocytosis induced by pyrimethamine; its teratogenic role.
Topics: Abnormalities, Drug-Induced; Animals; Erythrocytes; Erythrocytes, Abnormal; Female; Fetal Diseases; | 1975 |