Page last updated: 2024-11-03

pyrimethamine and Fetal Death

pyrimethamine has been researched along with Fetal Death in 16 studies

Maloprim: contains above 2 cpds

Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.

Research Excerpts

ExcerptRelevanceReference
"We enrolled 1320 pregnant Malawian women in a randomized trial and treated them for malaria and other infections with either 2 doses of sulfadoxine-pyrimethamine (SP) (control), monthly SP, or monthly sulfadoxine-pyrimethamine and 2 doses of azithromycin (AZI-SP)."5.27Child Health Outcomes After Presumptive Infection Treatment in Pregnant Women: A Randomized Trial. ( Ashorn, P; Ashorn, U; Cheung, YB; Gladstone, M; Hallamaa, L; Kulmala, T; Luntamo, M; Maleta, K; Mangani, C, 2018)
"The frequency of chromosome aberrations in ovulated oocytes at metaphase, II subjected to pyrimethamine and 2,4,5-T, reached 6--8% and exceeded the control value in 5--10 times."1.26[Nature of cytogenetic and morphologic disorders in rat oogenesis and embryogenesis induced by chloridin and 2,4,5-trichlorophenoxyacetic acid during the preovulatory phase of meiosis]. ( Chebotar', NA, 1980)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hallamaa, L1
Cheung, YB1
Maleta, K1
Luntamo, M1
Ashorn, U1
Gladstone, M1
Kulmala, T1
Mangani, C1
Ashorn, P1
ALEZZANDRINI, AA1
HERNANDEZ, R1
Dyban, AP4
Akimova, IM3
Udalova, LD2
Pozhidaev, EA1
Chebotar', NA1
Popov, VB1
Puchkov, VF1
Cengir, SD1
Ortaç, F1
Söylemez, F1
Sharf, M1
Eibschitz, I1
Eylan, E1
Harrison, KA1
Ibeziako, PA1
Shitova, EM1
Kulikova, KV1
Pap, AG1
Tarakhovskiĭ, ML1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Lungwena Antenatal Intervention Study. A Single-centre Intervention Trial in Rural Malawi, Testing Maternal and Infant Health Effects of Presumptive Intermittent Treatment of Pregnant Women With Sulfadoxine-pyrimethamine and Azithromycin[NCT00131235]Phase 31,320 participants (Actual)Interventional2003-12-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pyrimethamine and Fetal Death

ArticleYear
[Theoretical and applied aspects of experimental teratology].
    Ontogenez, 1977, Volume: 8, Issue:6

    Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Dactinomycin; DNA Replication; Dose-Response Rela

1977

Trials

1 trial available for pyrimethamine and Fetal Death

ArticleYear
Child Health Outcomes After Presumptive Infection Treatment in Pregnant Women: A Randomized Trial.
    Pediatrics, 2018, Volume: 141, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Antimalarials; Azithromycin; Child Development; Child Health; Child Mo

2018

Other Studies

14 other studies available for pyrimethamine and Fetal Death

ArticleYear
[OCULAR TOXOPLASMOSIS].
    Archivos de oftalmologia de Buenos Aires, 1963, Volume: 38

    Topics: Atropine; Betamethasone; Clinical Laboratory Techniques; Epidemiology; Eye; Fetal Death; Humans; Mic

1963
[The significance of group B vitamins and genetic factors on the reaction of the rat embryo to thalidomide].
    Arkhiv anatomii, gistologii i embriologii, 1966, Volume: 51, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Diet; Drug Hypersensitivity; E

1966
[Relationship between the teratogenic effect and the chemical structure of drugs. Experiments with chloridine and bigumal].
    Doklady Akademii nauk SSSR, 1966, Mar-01, Volume: 167, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetus; Pregnancy; Proguanil; Pyrimethamin

1966
[Disorder of embryogenesis after the application of myelosan and chloridin on the female and male gametes in the rat].
    Arkhiv anatomii, gistologii i embriologii, 1966, Volume: 51, Issue:8

    Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Embryo, Mammalian; Female; Fetal Death; Gestational

1966
[Nature of cytogenetic and morphologic disorders in rat oogenesis and embryogenesis induced by chloridin and 2,4,5-trichlorophenoxyacetic acid during the preovulatory phase of meiosis].
    Genetika, 1980, Volume: 16, Issue:7

    Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Chromosome Aberrations; Cleavage Stage, Ovum; Embryo Los

1980
[Comparison of the effect of chloridin on rat embryos during postimplantation periods of development in vivo and in vitro].
    Ontogenez, 1977, Volume: 8, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Culture Techniques; Embryonic Development; Female; Fetal Death

1977
[Postimplantation development of rat embryos following application of injurious agents to male gametes].
    Arkhiv anatomii, gistologii i embriologii, 1976, Volume: 70, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Embryo Implantation; Female; Fetal D

1976
Treatment and results of chronic toxoplasmosis. Analysis of 33 cases.
    Gynecologic and obstetric investigation, 1992, Volume: 33, Issue:2

    Topics: Abortion, Spontaneous; Female; Fetal Death; Humans; Obstetric Labor, Premature; Pregnancy; Pregnancy

1992
[Anomalies in the development of rat embryo skeletons consequent to chlorid in (pyrimethamine) administration].
    Arkhiv anatomii, gistologii i embriologii, 1972, Volume: 63, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Bone and Bones; Female; Fetal Death;

1972
Latent toxoplasmosis and pregnancy.
    Obstetrics and gynecology, 1973, Volume: 42, Issue:3

    Topics: Abortion, Habitual; Antibodies; Female; Fetal Death; Glucose Tolerance Test; Humans; Obstetric Labor

1973
Maternal anaemia and fetal birthweight.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1973, Volume: 80, Issue:9

    Topics: Anemia; Anemia, Sickle Cell; Birth Weight; Blood Transfusion; Body Height; Chloroquine; Embryonic an

1973
[Study of early stages of embryogenesis of mammals with induced chromosomal aberrations].
    Arkhiv anatomii, gistologii i embriologii, 1970, Volume: 58, Issue:1

    Topics: Aneuploidy; Animals; Autoradiography; Chromosome Aberrations; Diploidy; DNA; Embryo, Mammalian; Embr

1970
[The state and psychophysical development of children born to mothers receiving antitoxoplasmosis treatment].
    Pediatriia, 1967, Volume: 46, Issue:9

    Topics: Adult; Congenital Abnormalities; Female; Fetal Death; Growth; Humans; Infant; Infant, Newborn; Infan

1967
[Effect of several drugs on the fetus].
    Akusherstvo i ginekologiia, 1967, Volume: 43, Issue:12

    Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Aspirin; Benzimidazoles; Chlorpromazine; Cortison

1967