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pyrimethamine and Experimental Neoplasms

pyrimethamine has been researched along with Experimental Neoplasms in 9 studies

Maloprim: contains above 2 cpds

Research Excerpts

ExcerptRelevanceReference
"Using the avian sarcoma virus (ASV) rat glioma model, we have evaluated the in vivo effectiveness of two lipid-soluble folate antagonists, metoprine (DDMP) and its 6-ethyl analog etoprine."7.66Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. ( Bigner, DD; Nichol, CA; Serano, RD; Sigel, CW, 1982)
"Using the avian sarcoma virus (ASV) rat glioma model, we have evaluated the in vivo effectiveness of two lipid-soluble folate antagonists, metoprine (DDMP) and its 6-ethyl analog etoprine."3.66Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. ( Bigner, DD; Nichol, CA; Serano, RD; Sigel, CW, 1982)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FISCHER, GA1
VONESSEN, CF1
Serano, RD1
Sigel, CW1
Nichol, CA1
Bigner, DD1
Hill, BT1
Price, LA1
Sirotnak, FM1
Moccio, DM1
Goutas, LJ1
Kelleher, LE1
Montgomery, JA1
Thong, YH1
Ferrante, A1
Kamali, F1
Gescher, A1
Slack, JA1
Baker, DC1
Hand, ES1
Plowman, J1
Rampal, JB1
Safavy, A1
Haugwitz, RD1
Narayanan, VL1
Cenedella, RJ1
Saxe, LH1
Van Dyke, K1

Reviews

1 review available for pyrimethamine and Experimental Neoplasms

ArticleYear
DDMP (2,4-diamino-5-(3',4'-dichlorophenyl)-methylpyrimidine).
    Cancer treatment reviews, 1980, Volume: 7, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Diarrhea; Drug Administrat

1980

Other Studies

8 other studies available for pyrimethamine and Experimental Neoplasms

ArticleYear
THE COMPARISON OF RADIATION AND ANTIMETABOLITE RESPONSES OF GENETICALLY ALTERED MURINE LEUKEMIC CELLS.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Animals; Antimetabolites; Chromosomes; Floxuridine; Genetics; Idoxuridine; Leukemia; Leukemia, Exper

1965
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Carmustine; Drug Therapy, Combination; Glioma

1982
Biochemical correlates of responsiveness and collateral sensitivity of some methotrexate-resistant murine tumors to the lipophilic antifolate, metoprine.
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Biological Transport; Cell Line; Drug Resistance; Formyltetrahydrofolates; Kinetics; Leukem

1982
Immunopotentiation by pyrimethamine in the mouse.
    Clinical and experimental immunology, 1980, Volume: 39, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Dose-Response Relationship, Drug; Hypersensitiv

1980
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 1977, Volume: 13

    Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines;

1977
Medicinal azides. Part 3. The metabolism of the investigational antitumour agent meta-azidopyrimethamine in mouse tissue in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:10

    Topics: Animals; Antineoplastic Agents; Azides; Kidney; Liver; Male; Mice; Mice, Inbred BALB C; Neoplasms, E

1988
Synthesis, chemical stability and pre-clinical anti-tumor activity of pyrazine diazohydroxide, sodium salt (NSC-361456).
    Anti-cancer drug design, 1987, Volume: 2, Issue:3

    Topics: Animals; Antineoplastic Agents; Azides; Drug Evaluation, Preclinical; Drug Stability; Female; Half-L

1987
An automated method of mass drug testing applied to screening for antimalarial activity.
    Chemotherapy, 1970, Volume: 15, Issue:3

    Topics: Animals; Antimalarials; Automation; Chloroquine; Erythrocytes; Glucose; Glycolysis; Lactates; Male;

1970