pyrimethamine has been researched along with Epilepsy, Absence in 1 studies
Maloprim: contains above 2 cpds
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of metoprine, an inhibitor of histamine N-methyltransferase, on open field activity and brain regional histamine (HA) content were examined in rats with mixed, absence and audiogenic, epilepsy (WAG/Rij-AGS), rats with audiogenic epilepsy (Wistar-AGS) and in non-epileptic control rats (Wistar-nAGS)." | 3.78 | Metoprine induced behavioral modifications and brain regional histamine increase in WAG/Rij and Wistar rats. ( Bazyan, AS; Birioukova, LM; Kuznetsova, GD; Midzyanovskaya, IS; Samotaeva, IS; Tuomisto, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samotaeva, IS | 1 |
| Birioukova, LM | 1 |
| Midzyanovskaya, IS | 1 |
| Kuznetsova, GD | 1 |
| Bazyan, AS | 1 |
| Tuomisto, L | 1 |
1 other study available for pyrimethamine and Epilepsy, Absence
| Article | Year |
|---|---|
Metoprine induced behavioral modifications and brain regional histamine increase in WAG/Rij and Wistar rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Electroencephalography; Enzyme Inhibitors; Epilepsy; Epi | 2012 |