pyrimethamine has been researched along with Disease Models, Animal in 52 studies
Maloprim: contains above 2 cpds
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of methylene blue (MB) combined with pyrimethamine (PYR), chloroquine (CQ) or quinine (Q) was examined in a classical four-day suppressive test against a causative agent of rodent malaria, Plasmodium berghei." | 7.78 | The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine. ( Aldana, I; Bertani, S; Deharo, E; Garavito, G; Quiliano, M; Valentin, A, 2012) |
| "The study was undertaken to examine the involvement of the renin-angiotensin system in the reversal by endogenous central histamine of critical haemorrhagic hypotension in anaesthetised Wistar rats." | 7.72 | Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentrations, after loading with histamine precursor L-histidine or inhibition of histamine N-methyltransferase (HNMT) activity, produces the reversal of critical hypotension with improvement in survival of haemorrhage-shocked rats." | 7.72 | Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "The effectiveness of combinations of rifabutin with atovaquone, clindamycin, pyrimethamine, or sulfadiazine in the treatment of toxoplasmic encephalitis in a murine model was investigated." | 7.69 | Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. ( Araujo, FG; Remington, JS; Suzuki, Y, 1996) |
| "Treatment with pyrimethamine decreases cell proliferation in human ADPKD cells and blocks renal cyst formation in an adult and a neonatal PKD mouse model." | 5.37 | Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways. ( Frank, DA; Haque, N; Humphreys, BD; Nelson, EA; Takakura, A; Zandi-Nejad, K; Zhou, J, 2011) |
| "Hence, this study was therefore aimed at evaluating the antimalarial activity of a probiotic bacterium Lactobacillus sakei isolated from traditionally fermented milk in mice infected with chloroquine sensitive Plasmodium berghei ANKA." | 4.02 | In vivo antimalarial activity of a probiotic bacterium Lactobacillus sakei isolated from traditionally fermented milk in BALB/c mice infected with Plasmodium berghei ANKA. ( Achidi, EA; Bila, RB; Feugaing Sofeu, DD; Ivo, EP; Taiwe, GS; Tatsinkou Fossi, B; Toukam, LL, 2021) |
| "Pyrimethamine-loaded nanomicelles showed potent antimalarial activity and can be considered as a potential candidate for further examination of their suitability as an antimalarial drug." | 3.96 | A new effective antiplasmodial compound: Nanoformulated pyrimethamine. ( Bide, VZ; Kalani, H; Nematolahy, P; Pestehchian, N; Vafaei, MR; Varshosaz, J; Yousefi, HA, 2020) |
| " Notably, the anti-parasitic drugs pyrimethamine and sulfadiazine, a standard treatment of toxoplasmosis, significantly reduced 3-HK and KYNA levels in the brain of infected mice when applied between 28 and 56 days post-infection." | 3.80 | Evaluation of kynurenine pathway metabolism in Toxoplasma gondii-infected mice: implications for schizophrenia. ( Fang, Q; Harris, TH; Horning, KJ; Hunter, CA; Notarangelo, FM; Schwarcz, R; Thomas, MA; Wilson, EH, 2014) |
| "The effectiveness of methylene blue (MB) combined with pyrimethamine (PYR), chloroquine (CQ) or quinine (Q) was examined in a classical four-day suppressive test against a causative agent of rodent malaria, Plasmodium berghei." | 3.78 | The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine. ( Aldana, I; Bertani, S; Deharo, E; Garavito, G; Quiliano, M; Valentin, A, 2012) |
| "RBx11160 (OZ277) is a promising antimalarial drug candidate that Ranbaxy Laboratories Limited and Medicines for Malaria Venture (MMV) are currently developing as a fixed combination with piperaquine." | 3.74 | In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models. ( Chollet, J; Santo-Tomas, J; Scheurer, C; Snyder, C; Wittlin, S, 2007) |
| "The study was undertaken to examine the involvement of the renin-angiotensin system in the reversal by endogenous central histamine of critical haemorrhagic hypotension in anaesthetised Wistar rats." | 3.72 | Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "An increase in endogenous central histamine concentrations, after loading with histamine precursor L-histidine or inhibition of histamine N-methyltransferase (HNMT) activity, produces the reversal of critical hypotension with improvement in survival of haemorrhage-shocked rats." | 3.72 | Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats. ( Jochem, J, 2004) |
| "The effectiveness of combinations of rifabutin with atovaquone, clindamycin, pyrimethamine, or sulfadiazine in the treatment of toxoplasmic encephalitis in a murine model was investigated." | 3.69 | Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice. ( Araujo, FG; Remington, JS; Suzuki, Y, 1996) |
| "Three standard antimalarials pyrimethamine, primaquine and quinine were tested against P." | 3.67 | Gametocytocidal and sporontocidal activity of some standard antimalarials on P. berghei (NK 65) infection M. natalensis. ( Pal, NL; Rastogi, M; Sen, AB, 1989) |
| "In this study, the effects of the treatment with different doses of fluconazole (FLZ) in combination with the current treatment of acute toxoplasmosis on reducing the mortality rate and the parasitic load in the murine model in vivo were studied." | 1.62 | Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine. ( Anita, M; Hadi, M; Mohammad, JM; Reza, S; Sina, S; Soudabeh, E, 2021) |
| "The aim of this study is to evaluate the effects of pyrimethamine (PYR) and sulfadiazine (SDZ) combined with levamisole and echinacea on the survival of mice infected with Toxoplasma gondii." | 1.43 | In Vivo Efficacy of Drugs against Toxoplasma gondii Combined with Immunomodulators. ( Bilgin, K; Hokelek, M; Köksal, ZŞ; Yanik, K; Yılmaz, EM, 2016) |
| "Pyrimethamine was radioiodinated with I-131." | 1.39 | Preparation of (131)I-Pyrimethamine and evaluation for scintigraphy of experimentally Toxoplasma gondii-infected rats. ( Baykara, B; Bekis, R; Durkan, K; Inceboz, T; Surucu, E; Uner, A; Yavasoglu, A; Yilmaz, O; Yurt Lambrecht, F, 2013) |
| "Fluconazole is an important antifungal triazole used against others CNS related opportunistic pathogens such as Cryptococcus neoformans and Candida spp." | 1.39 | Toxoplasma gondii: the effect of fluconazole combined with sulfadiazine and pyrimethamine against acute toxoplasmosis in murine model. ( de Souza, W; Martins-Duarte, ÉS; Vommaro, RC, 2013) |
| "Malaria is one of the leading causes of severe infectious disease worldwide; yet, our ability to maintain effective therapy to combat the illness is continually challenged by the emergence of drug resistance." | 1.37 | Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice. ( Bathurst, I; Buckner, FS; Burrows, J; Charman, SA; Charman, WN; Creason, S; Deng, X; El Mazouni, F; Floyd, DM; Gujjar, R; Matthews, D; Phillips, MA; Rathod, PK; Shackleford, DM; White, J; White, KL, 2011) |
| "Treatment with pyrimethamine decreases cell proliferation in human ADPKD cells and blocks renal cyst formation in an adult and a neonatal PKD mouse model." | 1.37 | Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways. ( Frank, DA; Haque, N; Humphreys, BD; Nelson, EA; Takakura, A; Zandi-Nejad, K; Zhou, J, 2011) |
| " Three doses of 200, 300 and 400 mg/kg DFO were used either alone or in combination with pyrimethamine." | 1.30 | Effect of deferoxamine alone and combined with pyrimethamine on acute toxoplasmosis in mice. ( Mahmoud, MS, 1999) |
| " Extending these experiments, we have now shown that roxithromycin at doses of 400 or 200 mg/kg/day combined with dapsone at doses of 5, 25 or 50 mg/kg/day completely prevented the development of T." | 1.30 | Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. ( Brun-Pascaud, M; Chau, F; Derouin, F; Girard, PM, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (19.23) | 18.7374 |
| 1990's | 11 (21.15) | 18.2507 |
| 2000's | 10 (19.23) | 29.6817 |
| 2010's | 14 (26.92) | 24.3611 |
| 2020's | 7 (13.46) | 2.80 |
| Authors | Studies |
|---|---|
| Jiménez-Díaz, MB | 1 |
| Mulet, T | 1 |
| Viera, S | 1 |
| Gómez, V | 1 |
| Garuti, H | 1 |
| Ibáñez, J | 1 |
| Alvarez-Doval, A | 1 |
| Shultz, LD | 1 |
| Martínez, A | 1 |
| Gargallo-Viola, D | 1 |
| Angulo-Barturen, I | 1 |
| Gujjar, R | 1 |
| El Mazouni, F | 1 |
| White, KL | 1 |
| White, J | 1 |
| Creason, S | 1 |
| Shackleford, DM | 1 |
| Deng, X | 1 |
| Charman, WN | 1 |
| Bathurst, I | 1 |
| Burrows, J | 1 |
| Floyd, DM | 1 |
| Matthews, D | 1 |
| Buckner, FS | 1 |
| Charman, SA | 2 |
| Phillips, MA | 1 |
| Rathod, PK | 1 |
| Lourido, S | 1 |
| Zhang, C | 1 |
| Lopez, MS | 1 |
| Tang, K | 1 |
| Barks, J | 1 |
| Wang, Q | 3 |
| Wildman, SA | 1 |
| Shokat, KM | 1 |
| Sibley, LD | 1 |
| Mendoza-Martínez, C | 1 |
| Correa-Basurto, J | 1 |
| Nieto-Meneses, R | 1 |
| Márquez-Navarro, A | 1 |
| Aguilar-Suárez, R | 1 |
| Montero-Cortes, MD | 1 |
| Nogueda-Torres, B | 1 |
| Suárez-Contreras, E | 1 |
| Galindo-Sevilla, N | 1 |
| Rojas-Rojas, Á | 1 |
| Rodriguez-Lezama, A | 1 |
| Hernández-Luis, F | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 3 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Pestehchian, N | 1 |
| Vafaei, MR | 1 |
| Nematolahy, P | 1 |
| Varshosaz, J | 1 |
| Yousefi, HA | 1 |
| Bide, VZ | 1 |
| Kalani, H | 1 |
| Minuzzi, CE | 1 |
| Portella, LP | 1 |
| Bräunig, P | 1 |
| Sangioni, LA | 1 |
| Ludwig, A | 1 |
| Ramos, LS | 1 |
| Pacheco, L | 1 |
| Silva, CR | 1 |
| Pacheco, FC | 1 |
| Menegolla, IA | 1 |
| Farinha, LB | 1 |
| Kist, PP | 1 |
| Breganó, RM | 1 |
| Nino, BSL | 1 |
| Cardoso Martins, FD | 1 |
| Monica, TC | 1 |
| Ferreira, FP | 1 |
| Britto, I | 1 |
| Signori, A | 1 |
| Medici, KC | 1 |
| Freire, RL | 1 |
| Garcia, JL | 1 |
| Navarro, IT | 1 |
| Difante, CM | 1 |
| Flores Vogel, FS | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 4 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
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| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
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| Lymperopoulos, N | 1 |
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| Hahn, S | 3 |
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| Ling, J | 2 |
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| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
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| Li, X | 10 |
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| Abdul Wafi, S | 1 |
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| Liu, ZM | 1 |
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| Zhou, B | 1 |
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| Xing, YL | 1 |
| Chen, MA | 1 |
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| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 2 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Wu, G | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Chen, L | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Wang, J | 4 |
| Zhang, E | 1 |
| Zhang, J | 3 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
| Wang, Y | 2 |
| Meng, J | 1 |
| Chen, G | 2 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
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| Leuschner, R | 1 |
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| Nave, S | 1 |
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| Li, J | 7 |
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| Hou, J | 1 |
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| Gao, C | 1 |
| Pang, D | 1 |
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| Wang, L | 1 |
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| Zhuang, T | 1 |
| Tu, J | 1 |
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| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 6 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
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| Wei, Y | 2 |
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| Na, KJ | 1 |
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| Tadelle, RM | 1 |
| Saad, MJA | 1 |
| Oliveira, AG | 1 |
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| Bronzo, P | 1 |
| Banach, M | 1 |
| Sahebkar, A | 1 |
| Mannarino, MR | 1 |
| Pirro, M | 1 |
| Patsourakos, NG | 1 |
| Kouvari, M | 1 |
| Kotidis, A | 1 |
| Kalantzi, KI | 1 |
| Tsoumani, ME | 1 |
| Anastasiadis, F | 1 |
| Andronikos, P | 1 |
| Aslanidou, T | 1 |
| Efraimidis, P | 1 |
| Georgiopoulos, A | 1 |
| Gerakiou, K | 1 |
| Grigoriadou-Skouta, E | 1 |
| Grigoropoulos, P | 1 |
| Hatzopoulos, D | 1 |
| Kartalis, A | 1 |
| Lyras, A | 1 |
| Markatos, G | 1 |
| Mikrogeorgiou, A | 1 |
| Myroforou, I | 1 |
| Orkopoulos, A | 1 |
| Pavlidis, P | 1 |
| Petras, C | 1 |
| Riga, M | 1 |
| Skouloudi, M | 1 |
| Smyrnioudis, N | 1 |
| Thomaidis, K | 1 |
| Tsikouri, GE | 1 |
| Tsikouris, EI | 1 |
| Zisimos, K | 1 |
| Vavoulis, P | 1 |
| Vitali, MG | 1 |
| Vitsas, G | 1 |
| Vogiatzidis, C | 1 |
| Chantanis, S | 1 |
| Fousas, S | 1 |
| Panagiotakos, DB | 1 |
| Tselepis, AD | 1 |
| Jungen, C | 1 |
| Alken, FA | 1 |
| Eickholt, C | 1 |
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| Kuklik, P | 1 |
| Klatt, N | 1 |
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2 reviews available for pyrimethamine and Disease Models, Animal
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Controlling malaria and African trypanosomiasis: the role of the mouse.
Topics: Animals; Disease Models, Animal; Disease Progression; Drug Resistance; Genetic Linkage; Genetic Pred | 2005 |
1 trial available for pyrimethamine and Disease Models, Animal
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
50 other studies available for pyrimethamine and Disease Models, Animal
| Article | Year |
|---|---|
Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Erythrocytes; | 2009 |
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.
Topics: Animals; Antimalarials; Dihydroorotate Dehydrogenase; Disease Models, Animal; Drug Design; Drug Disc | 2011 |
Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii.
Topics: Animals; Base Sequence; Disease Models, Animal; DNA Primers; Enzyme-Linked Immunosorbent Assay; Mice | 2013 |
Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents.
Topics: Administration, Oral; Animals; Antimalarials; Antiprotozoal Agents; Chlorocebus aethiops; Disease Mo | 2015 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
A new effective antiplasmodial compound: Nanoformulated pyrimethamine.
Topics: Animals; Antimalarials; Disease Models, Animal; Drug Compounding; Liver; Malaria; Male; Mice; Micell | 2020 |
Isolation and molecular characterization of Toxoplasma gondii from placental tissues of pregnant women who received toxoplasmosis treatment during an outbreak in southern Brazil.
Topics: Animals; Brazil; Coccidiostats; Disease Models, Animal; Disease Outbreaks; Female; Genotype; Humans; | 2020 |
Determination of parasitic burden in the brain tissue of infected mice in acute toxoplasmosis after treatment by fluconazole combined with sulfadiazine and pyrimethamine.
Topics: 14-alpha Demethylase Inhibitors; Acute Disease; Animals; Antiprotozoal Agents; Brain; Disease Models | 2021 |
In vivo antimalarial activity of a probiotic bacterium Lactobacillus sakei isolated from traditionally fermented milk in BALB/c mice infected with Plasmodium berghei ANKA.
Topics: Animals; Antimalarials; Cameroon; Chloroquine; Disease Models, Animal; Drug Combinations; Fermented | 2021 |
Chloroquine and pyrimethamine inhibit the replication of human respiratory syncytial virus A.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Chloroquine; Disease Models, Animal; Female; Hu | 2021 |
The STAT3 inhibitor pyrimethamine displays anti-cancer and immune stimulatory effects in murine models of breast cancer.
Topics: Adjuvants, Immunologic; Animals; Anti-Infective Agents; Antineoplastic Agents; Breast Neoplasms; CD8 | 2018 |
Derivatives of a benzoquinone acyl hydrazone with activity against Toxoplasma gondii.
Topics: Animals; Antiparasitic Agents; Benzoquinones; Cell Line; Disease Models, Animal; Drug Discovery; Fem | 2018 |
Evaluation of kynurenine pathway metabolism in Toxoplasma gondii-infected mice: implications for schizophrenia.
Topics: Animals; Anti-Infective Agents; Brain; Disease Models, Animal; Drug Combinations; Female; Kynurenic | 2014 |
In Vivo Efficacy of Drugs against Toxoplasma gondii Combined with Immunomodulators.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Disease Models, Animal; Drug Therapy, Combinati | 2016 |
Effects of Thymus vulgaris ethanolic extract on chronic toxoplasmosis in a mouse model.
Topics: Animals; Brain; Chronic Disease; Disease Models, Animal; Ethanol; Humans; Male; Mice; Plant Extracts | 2016 |
Methylene blue inhibits lumefantrine-resistant Plasmodium berghei.
Topics: Animals; Antimalarials; Disease Models, Animal; Drug Resistance; Drug-Related Side Effects and Adver | 2016 |
Azithromycin reduces ocular infection during congenital transmission of toxoplasmosis in the Calomys callosus model.
Topics: Animals; Anti-Infective Agents; Antiprotozoal Agents; Azithromycin; Brain; Disease Models, Animal; D | 2009 |
Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways.
Topics: Adult; Aminosalicylic Acids; Animals; Animals, Newborn; Benzenesulfonates; Cell Line; Cysts; Disease | 2011 |
Mosquito infection studies with Aotus monkeys and humans infected with the Chesson strain of Plasmodiun vivax.
Topics: Animals; Anopheles; Antimalarials; Aotidae; Chloroquine; Disease Management; Disease Models, Animal; | 2012 |
The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine.
Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhib | 2012 |
Preparation of (131)I-Pyrimethamine and evaluation for scintigraphy of experimentally Toxoplasma gondii-infected rats.
Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Drug Compounding; Drug Stability; Iodine Radi | 2013 |
Toxoplasma gondii: the effect of fluconazole combined with sulfadiazine and pyrimethamine against acute toxoplasmosis in murine model.
Topics: Acute Disease; Animals; Antifungal Agents; Antiprotozoal Agents; Cell Line; Cell Survival; Disease M | 2013 |
Effect of deferoxamine alone and combined with pyrimethamine on acute toxoplasmosis in mice.
Topics: Acute Disease; Animals; Antiprotozoal Agents; Deferoxamine; Disease Models, Animal; Drug Therapy, Co | 1999 |
Congenital toxoplasmosis: therapeutic strategies.
Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; | 2003 |
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain Chemistry; C | 2004 |
Involvement of proopiomenalocortin-derived peptides in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Adrenocorticotropic Hormone; alpha-MSH; Animals; Brain Chemistry; Disease Models, Animal; Heart Rate | 2004 |
Role of histaminergic neurons in development of epileptic seizures in EL mice.
Topics: Animals; Brain; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Epilepsy; Epil | 2004 |
Improved transfection and new selectable markers for the rodent malaria parasite Plasmodium yoelii.
Topics: Animals; Antimalarials; Disease Models, Animal; Drug Resistance; Electroporation; Female; Green Fluo | 2006 |
Plasmodium yoelii yoelii 17XNL constitutively expressing GFP throughout the life cycle.
Topics: Animals; Anopheles; Antimalarials; Disease Models, Animal; Drug Resistance; Erythrocytes; Flow Cytom | 2007 |
In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Atovaquone; Disease Models, Animal; Drug Interacti | 2007 |
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Tria | 1994 |
Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine.
Topics: AIDS-Related Opportunistic Infections; Animals; Clarithromycin; Disease Models, Animal; Dose-Respons | 1994 |
Use of rifabutin in combination with atovaquone, clindamycin, pyrimethamine, or sulfadiazine for treatment of toxoplasmic encephalitis in mice.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal Agents; Atovaquone; Brain; Clin | 1996 |
Toxoplasmosis: a scenic change and a change of therapy?
Topics: Animals; Coccidiostats; Disease Models, Animal; Macaca mulatta; Polymerase Chain Reaction; Pyrimetha | 1997 |
Prenatal diagnosis and treatment of congenital Toxoplasma gondii infections: an experimental study in rhesus monkeys.
Topics: Amniotic Fluid; Animals; Anti-Infective Agents; Disease Models, Animal; DNA, Protozoan; DNA, Ribosom | 1997 |
Lack of therapeutic effect of colchicine on murine toxoplasmosis.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Colchicine; Diarrhea; Disease Models, Animal; | 1998 |
Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Disease Models, Animal; Dose-Respons | 1998 |
Studies on infections with two strains of Plasmodium inui from Taiwan in rhesus monkeys and different anopheline mosquitoes.
Topics: Animals; Anopheles; Antimalarials; Disease Models, Animal; Host-Parasite Interactions; Insect Vector | 1998 |
Nifurtimox plus pyrimethamine for treatment of murine toxoplasmosis.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Disease Models, Animal; Dose-Response Relations | 1998 |
Plasmodium cynomolgi: transfection of blood-stage parasites using heterologous DNA constructs.
Topics: Animals; Antimalarials; Disease Models, Animal; DNA Primers; DNA, Protozoan; Drug Resistance; Electr | 1999 |
Plasmodium falciparum and Plasmodium vivax infections in the owl monkey (Aotus trivirgatus). II. Responses to chloroquine, quinine, and pyrimethamine.
Topics: Animals; Aotus trivirgatus; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; F | 1978 |
Chemotherapy of Plasmodium vivax in Saimiri and Aotus models.
Topics: Administration, Oral; Animals; Chloroquine; Disease Models, Animal; Drug Combinations; Drug Evaluati | 1975 |
Evaluating new antimalarial drugs against trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys.
Topics: Amodiaquine; Animals; Antimalarials; Dapsone; Disease Models, Animal; Dose-Response Relationship, Dr | 1976 |
Chadwick lecture. Cerebral malaria--the quest for suitable experimental models in parasitic diseases of man.
Topics: Africa; Animals; Brain; Brain Diseases; Disease Models, Animal; Drug Resistance; Haplorhini; Humans; | 1976 |
The effect of sulfomethoxypyrazine-pyrimethamine therapy on the fine structure of Toxoplasma gondii-cysts in the brain of Mastomys natalensis. Scanning and transmission electron microscopical investigations.
Topics: Animals; Brain; Disease Models, Animal; Drug Therapy, Combination; Female; Male; Mammals; Pyrimetham | 1977 |
Gametocytocidal and sporontocidal activity of some standard antimalarials on P. berghei (NK 65) infection M. natalensis.
Topics: Animals; Disease Models, Animal; Female; Malaria; Muridae; Plasmodium berghei; Primaquine; Pyrimetha | 1989 |
Adaptation of the Indochina I/CDC strain of Plasmodium falciparum to the squirrel monkey (Saimiri sciureus).
Topics: Animals; Aotus trivirgatus; Cebidae; Chloroquine; Disease Models, Animal; Drug Resistance; Malaria; | 1986 |
[Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse].
Topics: Aminobenzoates; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syn | 1973 |
Infections with Plasmodium falciparum and Plasmodium vivax in the owl monkey--model systems for basic biological and chemotherapeutic studies.
Topics: Animal Feed; Animals; Butylamines; Chlorobenzenes; Chloroquine; Colombia; Darkness; Disease Models, | 1973 |
Erythrocyte glucose-6-phosphate dehydrogenase and glutathione deficiency in sheep.
Topics: Age Factors; Animals; Chromium Isotopes; Disease Models, Animal; Erythrocytes; Female; Glucosephosph | 1972 |