Page last updated: 2024-11-03

pyrimethamine and Dermatomyositis

pyrimethamine has been researched along with Dermatomyositis in 3 studies

Maloprim: contains above 2 cpds

Dermatomyositis: A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6)

Research Excerpts

ExcerptRelevanceReference
"We report a 59-year-old woman with severe dermatomyositis in association with high serum toxoplasma antibody titres who was successfully treated with pyrimethamine and sulphadiazine."3.68Dermatomyositis responding to treatment of associated toxoplasmosis. ( Allen, BR; Harland, CC; Marsden, JR; Vernon, SA, 1991)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harland, CC1
Marsden, JR1
Vernon, SA1
Allen, BR1
Wilfert, H1
Tappeiner, G1
Kagen, LJ1
Kimball, AC1
Christian, CL1

Other Studies

3 other studies available for pyrimethamine and Dermatomyositis

ArticleYear
Dermatomyositis responding to treatment of associated toxoplasmosis.
    The British journal of dermatology, 1991, Volume: 125, Issue:1

    Topics: Dermatomyositis; Drug Therapy, Combination; Female; Fundus Oculi; Hand; Humans; Middle Aged; Pyrimet

1991
[Toxoplasma infection in dermatomyositis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1988, Volume: 39, Issue:10

    Topics: Adult; Dermatomyositis; Diagnosis, Differential; Drug Therapy, Combination; Erythema Multiforme; Fem

1988
Serologic evidence of toxoplasmosis among patients with polymyositis.
    The American journal of medicine, 1974, Volume: 56, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Antibodies; Child; Child, Preschool; Complement Fi

1974