Page last updated: 2024-11-03

pyrimethamine and Day Blindness

pyrimethamine has been researched along with Day Blindness in 9 studies

Maloprim: contains above 2 cpds

Research Excerpts

ExcerptRelevanceReference
"A randomized double-blind study was performed to compare the side effects of long-term chemoprophylaxis of malaria with Fansidar (1 tablet a week) with those of a 300-mg weekly chloroquine regimen."5.05Tolerability of long-term prophylaxis with fansidar: a randomized double-blind study in Nigeria. ( Leimer, R; Stemberger, H; Wiedermann, G, 1984)
"The overall functional prognosis of congenital toxoplasmosis is better than would be expected on the basis of literature findings, with only 2 of the 130 children suffering bilateral visual impairment."1.33Ocular manifestations in congenital toxoplasmosis. ( Binquet, C; Denis, P; Fleury, J; Garweg, JG; Kodjikian, L; Peyron, F; Wallon, M, 2006)
"Many children with congenital toxoplasmosis have substantial retinal damage at birth and consequent loss of vision."1.30Eye manifestations of congenital toxoplasmosis. ( Boyer, KM; Holfels, E; Hopkins, J; Luciano, R; Mack, D; McLeod, R; Meier, P; Mets, MB; Patel, D; Remington, JS; Roizen, N; Stein, L; Stein, M; Swisher, CN; Withers, S, 1997)
"Seventeen of 18 children without hydrocephalus and six of eight children with obstructive hydrocephalus responsive to shunting had normal or near-normal neurologic and developmental outcomes."1.29Neurologic and developmental outcome in treated congenital toxoplasmosis. ( Boyer, KM; Holfels, E; Hopkins, J; Meier, P; Mets, MB; Patel, D; Roizen, N; Stein, L; Stein, MA; Swisher, CN, 1995)
"Many children with congenital toxoplasmosis have substantial retinal damage at birth and consequent loss of vision."1.29Eye manifestations of congenital toxoplasmosis. ( Boyer, KM; Holfels, E; Hopkins, J; Luciano, R; Mack, D; McLeod, R; Meier, P; Mets, MB; Patel, D; Remington, JS; Roizen, N; Stein, L; Stein, M; Swisher, CN; Withers, S, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, PK1
Jianping, C1
Vasconcelos-Santos, DV1
Arruda, JSD1
Dutta Majumder, P1
Anthony, E1
Ganesh, SK1
Biswas, J1
Ling, HS1
Teoh, SC1
Agrawal, R1
Furtado, JM1
Toscano, M1
Castro, V1
Rodrigues, MW1
Kodjikian, L1
Wallon, M1
Fleury, J1
Denis, P1
Binquet, C1
Peyron, F1
Garweg, JG1
Stemberger, H1
Leimer, R1
Wiedermann, G1
Roizen, N3
Swisher, CN3
Stein, MA1
Hopkins, J3
Boyer, KM3
Holfels, E3
Mets, MB3
Stein, L3
Patel, D3
Meier, P3
Wei, ME1
Campbell, SH1
Taylor, C1
Stein, M2
Withers, S2
Mack, D2
Luciano, R2
Remington, JS2
McLeod, R2
Dralands, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis Uveitis[NCT02843438]72 participants (Actual)Interventional2010-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pyrimethamine and Day Blindness

ArticleYear
Tolerability of long-term prophylaxis with fansidar: a randomized double-blind study in Nigeria.
    Acta tropica, 1984, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Antimalarials; Blood Cell Count; Chloroquine; Clinical Trials as Topic; Double-Bl

1984

Other Studies

8 other studies available for pyrimethamine and Day Blindness

ArticleYear
Ocular Toxoplasmosis in Tropical Areas: Analysis and Outcome of 190 Patients from a Multicenter Collaborative Study.
    Ocular immunology and inflammation, 2018, Volume: 26, Issue:8

    Topics: Adolescent; Adult; Aged; Antibodies, Protozoan; Antiprotozoal Agents; Child; Child, Preschool; Femal

2018
Roth Spots in Ocular Toxoplasmosis.
    Ocular immunology and inflammation, 2016, Volume: 24, Issue:5

    Topics: Antiprotozoal Agents; Chorioretinitis; Diagnosis, Differential; Drug Therapy, Combination; Humans; I

2016
Ocular manifestations in congenital toxoplasmosis.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2006, Volume: 244, Issue:1

    Topics: Adolescent; Adult; Antibodies, Protozoan; Antiprotozoal Agents; Child; Child, Preschool; Chorioretin

2006
Neurologic and developmental outcome in treated congenital toxoplasmosis.
    Pediatrics, 1995, Volume: 95, Issue:1

    Topics: Child Development; Female; Humans; Hydrocephalus; Infant; Infant, Newborn; Intelligence; Longitudina

1995
Precipitous visual loss secondary to optic nerve toxoplasmosis as an unusual presentation of AIDS.
    Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Drug Therap

1996
Eye manifestations of congenital toxoplasmosis.
    American journal of ophthalmology, 1996, Volume: 122, Issue:3

    Topics: Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Drug Therapy, Combination; Female

1996
Eye manifestations of congenital toxoplasmosis.
    American journal of ophthalmology, 1997, Volume: 123, Issue:1

    Topics: Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Choroid Diseases; Cicatrix; Femal

1997
[Harmful effects of common drugs on the visual apparatus. Anti-infective drugs. D. Antiprotozoal agents].
    Bulletin de la Societe belge d'ophtalmologie, 1972, Volume: 160, Issue:1

    Topics: Amidines; Antiprotozoal Agents; Blindness; Eye Diseases; Humans; Metronidazole; Papilledema; Photose

1972