Page last updated: 2024-11-03

pyrimethamine and Cryptosporidium Infection

pyrimethamine has been researched along with Cryptosporidium Infection in 4 studies

Maloprim: contains above 2 cpds

Research Excerpts

ExcerptRelevanceReference
" Sulfadoxine-pyrimethamine (SP), given for intermittent preventive therapy of malaria in pregnancy (IPTp), is one of few existing interventions that improves outcomes of both mother and baby despite widespread SP-resistant malaria."5.51The positive effect of malaria IPTp-SP on birthweight is mediated by gestational weight gain but modifiable by maternal carriage of enteric pathogens. ( Bartelt, LA; Carroll, I; Chinkhumba, J; Gutman, JR; Itoh, M; Juliano, JJ; Kayange, M; Mathanga, DP; McQuade, ETR; Meshnick, SR; Mzembe, E; Operario, DJ; Puerto-Meredith, SM; Waltmann, A, 2022)
"The anticryptosporidial activity of four macrolides alone and in combination with other antimicrobial agents was investigated against ten clinical isolates of Cryptosporidium parvum recovered from stools of AIDS patients."1.29In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum. ( Cirioni, O; Giacometti, A; Scalise, G, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Waltmann, A1
McQuade, ETR1
Chinkhumba, J1
Operario, DJ1
Mzembe, E1
Itoh, M1
Kayange, M1
Puerto-Meredith, SM1
Mathanga, DP1
Juliano, JJ1
Carroll, I1
Bartelt, LA1
Gutman, JR1
Meshnick, SR1
Giacometti, A1
Cirioni, O1
Scalise, G1
Miller, JM1
Boyd, HA1
Ostrowski, SR1
Cookson, ST1
Parise, ME1
Gonzaga, PS1
Addiss, DG1
Wilson, M1
Nguyen-Dinh, P1
Wahlquist, SP1
Weld, LH1
Wainwright, RB1
Gushulak, BD1
Cetron, MS1
Walker, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Single-course Malaria Chemoprevention on Clearance of and Protection From Plasmodium Falciparum Infection in the Presence of Resistance-associated Genotypes in Cameroon[NCT06173206]Phase 3900 participants (Anticipated)Interventional2024-03-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pyrimethamine and Cryptosporidium Infection

ArticleYear
The positive effect of malaria IPTp-SP on birthweight is mediated by gestational weight gain but modifiable by maternal carriage of enteric pathogens.
    EBioMedicine, 2022, Volume: 77

    Topics: Antimalarials; Birth Weight; Cryptosporidiosis; Cryptosporidium; Drug Combinations; Escherichia coli

2022

Other Studies

3 other studies available for pyrimethamine and Cryptosporidium Infection

ArticleYear
In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Artemisin

1996
Malaria, intestinal parasites, and schistosomiasis among Barawan Somali refugees resettling to the United States: a strategy to reduce morbidity and decrease the risk of imported infections.
    The American journal of tropical medicine and hygiene, 2000, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Coccidiosis; Cryptosporidi

2000
Opportunistic infections studies update.
    NIAID AIDS agenda, 1995,Spring

    Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antitubercular Agents; Atovaquone; Candidiasi

1995