Page last updated: 2024-11-03

pyrimethamine and Complications, Pregnancy

pyrimethamine has been researched along with Complications, Pregnancy in 33 studies

Maloprim: contains above 2 cpds

Research Excerpts

ExcerptRelevanceReference
"Mefloquine was more efficacious than sulfadoxine-pyrimethamine in HIV-uninfected women or daily cotrimoxazole prophylaxis in HIV-infected pregnant women for prevention of malaria infection and was associated with lower risk of maternal anaemia, no adverse effects on pregnancy outcomes (such as stillbirths and abortions), and no effects on low birth weight and prematurity."8.98Mefloquine for preventing malaria in pregnant women. ( Aponte, JJ; González, R; Menéndez, C; Piqueras, M; Pons-Duran, C; Ter Kuile, FO, 2018)
"Increasing resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) threatens its usefulness for intermittent preventive treatment in pregnancy (IPTp-SP)."8.02Evaluation of the usefulness of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine in a context with increased resistance of Plasmodium falciparum in Kingasani Hospital, Kinshasa in the Democratic Republic of Congo. ( DeMol, P; Devleesschauwer, B; Hayette, MP; Kabututu, PZ; Kayiba, NK; Lusamba, PD; Mukomena, ES; Mvumbi, DM; Mvumbi, GL; Rosas-Aguirre, A; Speybroeck, N; Tchakounang, VRK; Yobi, DM, 2021)
"Intermittent preventive treatment during pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is widely recommended in sub-Saharan Africa to reduce the risk of malaria and improve birth outcomes."7.79Intermittent preventive therapy with sulfadoxine-pyrimethamine for malaria in pregnancy: a cross-sectional study from Tororo, Uganda. ( Ades, V; Arinaitwe, E; Chang, M; Dorsey, G; Filler, S; Kamya, MR; Mugagga, O; Nasr, S; Ninsiima, B; Patil, TS; Schwartz, A; Walakira, A, 2013)
"The World Health Organization (WHO) recommends using insecticide-treated mosquito nets (ITNs) and intermittent preventive treatment with sulphadoxine-pyrimethamine (IPT-SP) to prevent malaria in sub-Saharan Africa."7.77Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire. ( Coffie, PA; Dabis, F; Eholie, SP; Ekouevi, DK; Kanhon, S; Kone, M; Kouakou, F; Menan, H; Sloan, C; Vanga-Bosson, HA, 2011)
"Mefloquine was more efficacious than sulfadoxine-pyrimethamine in HIV-uninfected women or daily cotrimoxazole prophylaxis in HIV-infected pregnant women for prevention of malaria infection and was associated with lower risk of maternal anaemia, no adverse effects on pregnancy outcomes (such as stillbirths and abortions), and no effects on low birth weight and prematurity."4.98Mefloquine for preventing malaria in pregnant women. ( Aponte, JJ; González, R; Menéndez, C; Piqueras, M; Pons-Duran, C; Ter Kuile, FO, 2018)
"Intermittent preventive treatment (IPTp) for pregnant women with sulfadoxine-pyrimethamine (SP) is widely implemented for the prevention of malaria in pregnancy and adverse birth outcomes."4.31Impact of Intermittent Presumptive Treatment for Malaria in Pregnancy on Hospital Birth Outcomes on the Kenyan Coast. ( Amadi, D; Bejon, P; Berkley, JA; Kamau, A; Musau, M; Mwakio, S; Nyaguara, A; Seale, AC; Snow, RW, 2023)
"Increasing resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) threatens its usefulness for intermittent preventive treatment in pregnancy (IPTp-SP)."4.02Evaluation of the usefulness of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine in a context with increased resistance of Plasmodium falciparum in Kingasani Hospital, Kinshasa in the Democratic Republic of Congo. ( DeMol, P; Devleesschauwer, B; Hayette, MP; Kabututu, PZ; Kayiba, NK; Lusamba, PD; Mukomena, ES; Mvumbi, DM; Mvumbi, GL; Rosas-Aguirre, A; Speybroeck, N; Tchakounang, VRK; Yobi, DM, 2021)
"In 2005, Nigeria changed its policy on prevention of malaria in pregnancy to intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp-SP)."3.88Prevalence of Low Birth Weight before and after Policy Change to IPTp-SP in Two Selected Hospitals in Southern Nigeria: Eleven-Year Retrospective Analyses. ( Adibe, MO; Aguwa, NC; Igboeli, NU; Ukwe, CV, 2018)
"At least 39 sub-Saharan African countries have policies on preventing malaria in pregnancy (MIP), including use of long-lasting insecticidal nets (LLINs), intermittent preventive treatment with sulphadoxine-pyrimethamine (IPTp-SP) and case management."3.80Assessment of the consistency of national-level policies and guidelines for malaria in pregnancy in five African countries. ( Andre, ZH; Dickerson, A; Eckert, E; Gomez, PP; Gutman, J; Hamel, MJ; Roman, E; Youll, S, 2014)
"Intermittent preventive treatment during pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is widely recommended in sub-Saharan Africa to reduce the risk of malaria and improve birth outcomes."3.79Intermittent preventive therapy with sulfadoxine-pyrimethamine for malaria in pregnancy: a cross-sectional study from Tororo, Uganda. ( Ades, V; Arinaitwe, E; Chang, M; Dorsey, G; Filler, S; Kamya, MR; Mugagga, O; Nasr, S; Ninsiima, B; Patil, TS; Schwartz, A; Walakira, A, 2013)
"The World Health Organization (WHO) recommends using insecticide-treated mosquito nets (ITNs) and intermittent preventive treatment with sulphadoxine-pyrimethamine (IPT-SP) to prevent malaria in sub-Saharan Africa."3.77Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire. ( Coffie, PA; Dabis, F; Eholie, SP; Ekouevi, DK; Kanhon, S; Kone, M; Kouakou, F; Menan, H; Sloan, C; Vanga-Bosson, HA, 2011)
" We recorded demographic data, antenatal prescription of intermittent preventive therapy during pregnancy with sulfadoxine-pyrimethamine and bed net use, and examined finger-prick blood for malaria parasites and hemoglobin concentration."3.76Decreasing burden of malaria in pregnancy in Malawian women and its relationship to use of intermittent preventive therapy or bed nets. ( Chaluluka, E; Feng, G; Molyneux, ME; Rogerson, SJ; Simpson, JA, 2010)
"Burkina Faso has recently changed the antimalarial drug policy to artesunate/amodiaquine or artemether/lumefantrine as the first-line antimalarial drug and sulfadoxine/pyrimethamine for the intermittent preventive treatment in pregnant woman."3.75[Change of antimalarial first-line treatment in Burkina Faso in 2005]. ( Diarra, A; Gansané, A; Konaté, AT; Nébié, I; Ouédraogo, A; Sirima, BS; Soulama, I; Tiono, A, 2009)
"The treatment of reference of congenital toxoplasmosis combines two folate synthesis inhibitors, pyrimethamine and an antibacterial sulfamide (sulfadiazine or sulfadoxine)."1.32[Maternal pancytopenia during antenatal treatment of congenital toxoplasmosis]. ( Coutty, N; Decocq, J; Delahousse, G; Detourmignies, L; Le Goueff, F; Mubiayi, N, 2004)
"We describe the case of a patient with systemic lupus erythematosus, treated by corticosteroids, who presented during two successive pregnancies with serological reactivation of toxoplasmosis associated with fetal lesions."1.29Recurrent congenital toxoplasmosis in a woman with lupus erythematosus. ( Blanc, B; Boubli, L; Casta, M; Chagnon, C; Cravello, L; D'Ercole, C; Franck, J; Harle, JR; Leclaire, M, 1995)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199015 (45.45)18.7374
1990's2 (6.06)18.2507
2000's2 (6.06)29.6817
2010's12 (36.36)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Kamau, A1
Musau, M1
Mwakio, S1
Amadi, D1
Nyaguara, A1
Bejon, P1
Seale, AC1
Berkley, JA1
Snow, RW1
Kayiba, NK1
Yobi, DM1
Tchakounang, VRK1
Mvumbi, DM1
Kabututu, PZ1
Devleesschauwer, B1
Mukomena, ES1
DeMol, P1
Hayette, MP1
Mvumbi, GL1
Rosas-Aguirre, A1
Lusamba, PD1
Speybroeck, N1
Velter, C1
Hotz, C1
Ingen-Housz-Oro, S1
Wolkenstein, P1
Fardet, L1
Igboeli, NU1
Adibe, MO1
Ukwe, CV1
Aguwa, NC1
Leke, AZ1
Dolk, H1
Loane, M1
Casson, K1
Maboh, NM1
Maeya, SE1
Ndumbe, LD1
Nyenti, PB1
Armstrong, O1
Etiendem, D1
González, R1
Pons-Duran, C1
Piqueras, M1
Aponte, JJ1
Ter Kuile, FO1
Menéndez, C1
Arinaitwe, E1
Ades, V1
Walakira, A1
Ninsiima, B1
Mugagga, O1
Patil, TS1
Schwartz, A1
Kamya, MR1
Nasr, S1
Chang, M1
Filler, S1
Dorsey, G1
Gomez, PP1
Gutman, J1
Roman, E1
Dickerson, A1
Andre, ZH1
Youll, S1
Eckert, E1
Hamel, MJ1
Mosha, D1
Chilongola, J1
Ndeserua, R1
Mwingira, F1
Genton, B1
Gansané, A1
Nébié, I1
Soulama, I1
Tiono, A1
Diarra, A1
Konaté, AT1
Ouédraogo, A1
Sirima, BS1
Feng, G1
Simpson, JA1
Chaluluka, E1
Molyneux, ME1
Rogerson, SJ1
Grietens, KP1
Gies, S1
Coulibaly, SO1
Ky, C1
Somda, J1
Toomer, E1
Muela Ribera, J1
D'Alessandro, U1
Maiga, AS1
Diakite, M1
Diawara, A1
Sango, HA1
Coulibaly, CO1
Vanga-Bosson, HA1
Coffie, PA1
Kanhon, S1
Sloan, C1
Kouakou, F1
Eholie, SP1
Kone, M1
Dabis, F1
Menan, H1
Ekouevi, DK1
Bertin, G1
Briand, V1
Bonaventure, D1
Carrieu, A1
Massougbodji, A1
Cot, M1
Deloron, P1
FILIPOWSKA, I1
BARBAROWSKI, H1
ISBRUCH, F1
THALHAMMER, O1
DELERUE, J1
MORLEY, D1
WOODLAND, M1
CUTHBERTSON, WF1
BEER, K1
OCKLITZ, HW1
SCHMITZ, HH1
ZIESCHE, H1
TENHUNEN, A1
ALEXANDER, M1
PULLON, DH1
Mubiayi, N1
Coutty, N1
Detourmignies, L1
Le Goueff, F1
Decocq, J1
Delahousse, G1
D'Ercole, C1
Boubli, L1
Franck, J1
Casta, M1
Harle, JR1
Chagnon, C1
Cravello, L1
Leclaire, M1
Blanc, B1
Cultrera, R1
Contini, C1
Hoffbrand, AV1
Schubert, S1
Granz, W1
Kupferschmidt, HG1
Harrison, KA1
Ibeziako, PA1
Prozorovskiĭ, VB1
Malakhovskiĭ, VG1
Fleming, AF1
Hendrickse, JP1
Allan, NC1

Reviews

1 review available for pyrimethamine and Complications, Pregnancy

ArticleYear
Mefloquine for preventing malaria in pregnant women.
    The Cochrane database of systematic reviews, 2018, 11-14, Volume: 11

    Topics: Anemia; Antimalarials; Drug Combinations; Drug Therapy, Combination; Female; HIV Seronegativity; Hum

2018

Trials

1 trial available for pyrimethamine and Complications, Pregnancy

ArticleYear
[Pharmacovigilance and impact of intermittent preventive treatment with sulfadoxine-pyrimethamine in pregnant women in Sélingué, Mali].
    Le Mali medical, 2010, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Anemia; Antimalarials; Drug Administration Schedule; Drug Combinations; Endemic D

2010

Other Studies

31 other studies available for pyrimethamine and Complications, Pregnancy

ArticleYear
Impact of Intermittent Presumptive Treatment for Malaria in Pregnancy on Hospital Birth Outcomes on the Kenyan Coast.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 02-08, Volume: 76, Issue:3

    Topics: Antimalarials; Drug Combinations; Female; Humans; Kenya; Malaria; Pregnancy; Pregnancy Complications

2023
Evaluation of the usefulness of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine in a context with increased resistance of Plasmodium falciparum in Kingasani Hospital, Kinshasa in the Democratic Republic of Congo.
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2021, Volume: 94

    Topics: Adolescent; Adult; Antimalarials; Democratic Republic of the Congo; Drug Combinations; Drug Resistan

2021
Stevens-Johnson Syndrome During Pregnancy: Case Report of a Newborn Treated With the Culprit Drug.
    JAMA dermatology, 2018, 02-01, Volume: 154, Issue:2

    Topics: Adult; Cesarean Section; Female; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Pregna

2018
Prevalence of Low Birth Weight before and after Policy Change to IPTp-SP in Two Selected Hospitals in Southern Nigeria: Eleven-Year Retrospective Analyses.
    BioMed research international, 2018, Volume: 2018

    Topics: Adult; Drug Combinations; Female; Gravidity; Humans; Infant, Low Birth Weight; Infant, Newborn; Mala

2018
First trimester medication use in pregnancy in Cameroon: a multi-hospital survey.
    BMC pregnancy and childbirth, 2018, Nov-20, Volume: 18, Issue:1

    Topics: Adult; Analgesics; Anti-Bacterial Agents; Antimalarials; Cameroon; Drug Combinations; Drug Prescript

2018
Intermittent preventive therapy with sulfadoxine-pyrimethamine for malaria in pregnancy: a cross-sectional study from Tororo, Uganda.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Adult; Cross-Sectional Studies; Dihydropteroate Synthase; Documentation; Drug Combinations; Drug Res

2013
Assessment of the consistency of national-level policies and guidelines for malaria in pregnancy in five African countries.
    Malaria journal, 2014, Jun-03, Volume: 13

    Topics: Africa; Antimalarials; Chemoprevention; Drug Combinations; Female; Health Policy; Health Services Re

2014
Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on placental malaria, maternal anaemia and birthweight in areas with high and low malaria transmission intensity in Tanzania.
    Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:9

    Topics: Adult; Anemia; Antimalarials; Birth Weight; Drug Combinations; Female; Humans; Infant, Low Birth Wei

2014
[Change of antimalarial first-line treatment in Burkina Faso in 2005].
    Bulletin de la Societe de pathologie exotique (1990), 2009, Volume: 102, Issue:1

    Topics: Animals; Antimalarials; Burkina Faso; Child, Preschool; Chloroquine; Female; Health Policy; Hemoglob

2009
Decreasing burden of malaria in pregnancy in Malawian women and its relationship to use of intermittent preventive therapy or bed nets.
    PloS one, 2010, Aug-06, Volume: 5, Issue:8

    Topics: Drug Combinations; Female; Hospitals; Humans; Longitudinal Studies; Malaria; Malawi; Mosquito Nets;

2010
Bottlenecks for high coverage of intermittent preventive treatment in pregnancy: the case of adolescent pregnancies in rural Burkina Faso.
    PloS one, 2010, Aug-06, Volume: 5, Issue:8

    Topics: Adolescent; Age Distribution; Attitude to Health; Burkina Faso; Drug Combinations; Female; Health Pr

2010
Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in Côte d'Ivoire.
    Malaria journal, 2011, Apr-29, Volume: 10

    Topics: Adolescent; Adult; Chemoprevention; Cote d'Ivoire; Cross-Sectional Studies; Drug Combinations; Drug

2011
Molecular markers of resistance to sulphadoxine-pyrimethamine during intermittent preventive treatment of pregnant women in Benin.
    Malaria journal, 2011, Jul-19, Volume: 10

    Topics: Adult; Antimalarials; Benin; Biomarkers; Chemoprevention; Clinical Trials as Topic; Dihydropteroate

2011
[Observations on daraprim and sulfonamide therapy of latent toxoplasmosis in women].
    Wiadomosci parazytologiczne, 1958, Volume: 4, Issue:3

    Topics: Antimalarials; Female; Humans; Pregnancy; Pregnancy Complications; Pyrimethamine; Sulfanilamide; Sul

1958
[Contributions to the problem of toxoplasmosis. I. Should we, at the present state of knowledge, treat pregnant women with positive toxoplasmosis titers, with daraprim and supronal?].
    Zentralblatt fur Gynakologie, 1960, Oct-01, Volume: 82

    Topics: Antimalarials; Drug Combinations; Pregnancy; Pregnancy Complications; Pyrimethamine; Sulfadiazine; S

1960
[The diagnosis and therapy of a toxoplasmosis infection in pregnancy. Birth of a healthy child in sulfonamide-pyrimethamine-treated lymph node toxoplasmosis in the 4th and 5th month of pregnancy].
    Deutsche medizinische Wochenschrift (1946), 1960, Jan-29, Volume: 85

    Topics: Antimalarials; Female; Humans; Lymph Nodes; Pregnancy; Pregnancy Complications; Pyrimethamine; Sulfa

1960
[TERATOGENIC ACTION OF DRUGS IN THE PREGNANT WOMAN].
    Journal des sciences medicales de Lille, 1963, Volume: 81

    Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Avitaminosis; Chlorpromazine; Cortisone; Female;

1963
CONTROLLED TRIAL OF PYRIMETHAMINE IN PREGNANT WOMEN IN AN AFRICAN VILLAGE.
    British medical journal, 1964, Mar-14, Volume: 1, Issue:5384

    Topics: Birth Weight; Chloroquine; Female; Humans; Infant; Infant Mortality; Lactose; Malaria; Nigeria; Preg

1964
[ACQUIRED TOXOPLASMOSIS].
    Schweizerische medizinische Wochenschrift, 1963, Nov-30, Volume: 93

    Topics: Communicable Disease Control; Communicable Diseases; Female; Humans; Pregnancy; Pregnancy Complicati

1963
[PREVENTION AND THERAPY OF CONNATAL TOXOPLASMOSIS].
    Kinderarztliche Praxis, 1963, Volume: 31

    Topics: Communicable Diseases; Epidemiology; Female; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy C

1963
GLANDULAR TOXOPLASMOSIS. OCCURRENCE OF THE DISEASE IN FINLAND.
    Acta pathologica et microbiologica Scandinavica. Supplementum, 1964, Volume: 172

    Topics: Biopsy; Diagnosis, Differential; Epidemiology; Female; Finland; Hodgkin Disease; Humans; Lymph Node

1964
[TOXOPLASMOSIS IN ADULTS].
    Zeitschrift fur arztliche Fortbildung (Berlin), 1965, Volume: 54

    Topics: Adult; Diagnosis; Encephalomyelitis; Female; Humans; Meningoencephalitis; Pregnancy; Pregnancy Compl

1965
THE TREATMENT OF GLANDULAR TOXOPLASMOSIS.
    The New Zealand medical journal, 1965, Volume: 64

    Topics: Child; Choroiditis; Drug Therapy; Female; Folic Acid; Humans; Lung Diseases; Lymphadenitis; Meningit

1965
[Maternal pancytopenia during antenatal treatment of congenital toxoplasmosis].
    Presse medicale (Paris, France : 1983), 2004, Aug-28, Volume: 33, Issue:14 Pt 1

    Topics: Adult; Antiprotozoal Agents; Drug Therapy, Combination; Female; Humans; Pancytopenia; Parity; Pregna

2004
Recurrent congenital toxoplasmosis in a woman with lupus erythematosus.
    Prenatal diagnosis, 1995, Volume: 15, Issue:12

    Topics: Adult; Amniotic Fluid; Animals; Anti-Infective Agents; Antibodies, Protozoan; Female; Fetal Diseases

1995
Management of a case of chloroquine-resistant falciparum malaria in a pregnant woman with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
    American journal of perinatology, 1999, Volume: 16, Issue:8

    Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; F

1999
Pathology of folate deficiency.
    Proceedings of the Royal Society of Medicine, 1977, Volume: 70, Issue:2

    Topics: Anemia, Megaloblastic; Female; Folic Acid Deficiency; Humans; Infertility; Male; Methotrexate; Pigme

1977
[Remarks on the drug prevention of malaria].
    Zeitschrift fur arztliche Fortbildung, 1985, Volume: 79, Issue:22

    Topics: Adult; Antimalarials; Child; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resi

1985
Maternal anaemia and fetal birthweight.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1973, Volume: 80, Issue:9

    Topics: Anemia; Anemia, Sickle Cell; Birth Weight; Blood Transfusion; Body Height; Chloroquine; Embryonic an

1973
[Range of teratogenic action as an indication of danger in using a medicinal preparation during pregnancy].
    Akusherstvo i ginekologiia, 1970, Volume: 46, Issue:9

    Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Female; Pregnancy; Pregnancy Complications; Pyrimeth

1970
The prevention of megaloblastic anaemia in pregnancy in Nigeria.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1968, Volume: 75, Issue:4

    Topics: Anemia, Hypochromic; Anemia, Macrocytic; Female; Folic Acid; Hemolysis; Humans; Malaria; Nigeria; Pr

1968