pyrimethamine has been researched along with Central Nervous System Disease in 21 studies
Maloprim: contains above 2 cpds
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixty-six newly diagnosed patients with acute nonlymphocytic leukemia received either daunorubicin alone or a combination of daunorubicin, cytosine arabinoside, 6-thioguanine, and pyrimethamine for remission-induction therapy." | 9.04 | Randomized clinical comparison of daunorubicin (NSC-82151) alone with a combination of daunorubicin, cytosine arabinoside (NSC-63878), 6-thioguanine (NSC-752), and pyrimethamine (NSC-3061) for the treatment of acute nonlymphocytic leukemia. ( Aisner, J; Fortner, C; Lichtenfeld, JL; O'Connell, MJ; Schiffer, CA; Schimpff, SC; Wiernik, PH, 1976) |
| "Thirty-five patients with the acquired immunodeficiency syndrome (AIDS) and central nervous system toxoplasmosis, seen over a 30-month period, were treated with the combination pyrimethamine/sulfadiazine." | 7.67 | Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy. ( Katlama, C; Leport, C; Marche, C; Matheron, S; Raffi, F; Regnier, B; Saimot, AG; Vedrenne, C; Vilde, JL, 1988) |
| "Three patients with acquired immune deficiency syndrome (AIDS), central nervous system toxoplasmosis, and hypersensitivity to sulfadiazine were given treatment with clindamycin plus pyrimethamine." | 7.67 | Role of clindamycin in the treatment of central nervous system toxoplasmosis. ( Hoy, J; Rolston, KV, 1987) |
| "We retrospectively examined 39 patients with AIDS and central nervous system toxoplasmosis in order to determine the efficacy and safety of two combinations: pyrimethamine-sulfadiazine and pyrimethamine-clindamycin." | 5.07 | Comparison of two medications in central nervous system toxoplasmosis in patients with AIDS. ( Ammassari, A; Antinori, A; Camilli, G; Damiano, F; Federico, G; Maiuro, G; Pizzigallo, E; Tamburrini, E, 1992) |
| "Sixty-six newly diagnosed patients with acute nonlymphocytic leukemia received either daunorubicin alone or a combination of daunorubicin, cytosine arabinoside, 6-thioguanine, and pyrimethamine for remission-induction therapy." | 5.04 | Randomized clinical comparison of daunorubicin (NSC-82151) alone with a combination of daunorubicin, cytosine arabinoside (NSC-63878), 6-thioguanine (NSC-752), and pyrimethamine (NSC-3061) for the treatment of acute nonlymphocytic leukemia. ( Aisner, J; Fortner, C; Lichtenfeld, JL; O'Connell, MJ; Schiffer, CA; Schimpff, SC; Wiernik, PH, 1976) |
| "Thirty-five patients with the acquired immunodeficiency syndrome (AIDS) and central nervous system toxoplasmosis, seen over a 30-month period, were treated with the combination pyrimethamine/sulfadiazine." | 3.67 | Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy. ( Katlama, C; Leport, C; Marche, C; Matheron, S; Raffi, F; Regnier, B; Saimot, AG; Vedrenne, C; Vilde, JL, 1988) |
| "Three patients with acquired immune deficiency syndrome (AIDS), central nervous system toxoplasmosis, and hypersensitivity to sulfadiazine were given treatment with clindamycin plus pyrimethamine." | 3.67 | Role of clindamycin in the treatment of central nervous system toxoplasmosis. ( Hoy, J; Rolston, KV, 1987) |
| "Early detection and treatment of congenital toxoplasmosis may reduce these sequelae." | 1.29 | Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. The New England Regional Toxoplasma Working Group. ( Abroms, I; Eaton, RB; Guerina, NG; Hoff, R; Hsu, HW; Lynfield, R; Maguire, JH; Meissner, HC; Pasternack, MS; Stechenberg, B, 1994) |
| "Forty-two cases of Toxoplasma gondii infection were analyzed, 25 in patients with neoplastic disease and 17 in apparently normal patients." | 1.27 | Toxoplasmosis. Problems in diagnosis and treatment. ( Armstrong, D; Hakes, TB, 1983) |
| "Toxoplasmosis is usually an asymptomatic infection, but symptomatic cases are becoming more common with the rise in AIDS cases and the increased number of patients receiving immunosuppressive therapy." | 1.27 | Toxoplasmosis of the central nervous system. ( Meredith, JT, 1987) |
| "Previously, CNS-toxoplasmosis has been noted to complicate lymphomas after initiation of anti-neoplastic therapy." | 1.26 | Favorable outcome of central nervous system toxoplasmosis occurring in a patient with untreated Hodgkin's disease. ( Cheson, BD; Green, JA; Spruance, SL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (71.43) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stack, A | 1 |
| Schott, HC | 1 |
| GENZ, H | 1 |
| Brewer, BD | 1 |
| Hakes, TB | 1 |
| Armstrong, D | 1 |
| Green, JA | 1 |
| Spruance, SL | 1 |
| Cheson, BD | 1 |
| Chute, JP | 1 |
| Decker, CF | 1 |
| Cotelingam, J | 1 |
| Guerina, NG | 1 |
| Hsu, HW | 1 |
| Meissner, HC | 1 |
| Maguire, JH | 1 |
| Lynfield, R | 1 |
| Stechenberg, B | 1 |
| Abroms, I | 1 |
| Pasternack, MS | 1 |
| Hoff, R | 1 |
| Eaton, RB | 1 |
| Wiernik, PH | 1 |
| Schimpff, SC | 1 |
| Schiffer, CA | 1 |
| Lichtenfeld, JL | 1 |
| Aisner, J | 1 |
| O'Connell, MJ | 1 |
| Fortner, C | 1 |
| Osieka, R | 1 |
| Schmidt, CG | 1 |
| Antinori, A | 1 |
| Ammassari, A | 1 |
| Maiuro, G | 1 |
| Camilli, G | 1 |
| Damiano, F | 1 |
| Federico, G | 1 |
| Pizzigallo, E | 1 |
| Tamburrini, E | 1 |
| Mitchell, CD | 1 |
| Erlich, SS | 1 |
| Mastrucci, MT | 1 |
| Hutto, SC | 1 |
| Parks, WP | 1 |
| Scott, GB | 1 |
| Pedrol, E | 1 |
| González-Clemente, JM | 1 |
| Gatell, JM | 1 |
| Mallolas, J | 1 |
| Miró, JM | 1 |
| Graus, F | 1 |
| Alvarez, R | 1 |
| Mercader, JM | 1 |
| Berenguer, J | 1 |
| Jiménez de Anta, MT | 1 |
| Leport, C | 1 |
| Raffi, F | 1 |
| Matheron, S | 1 |
| Katlama, C | 1 |
| Regnier, B | 1 |
| Saimot, AG | 1 |
| Marche, C | 1 |
| Vedrenne, C | 1 |
| Vilde, JL | 1 |
| Meredith, JT | 1 |
| Rolston, KV | 1 |
| Hoy, J | 1 |
| Ragab, AH | 1 |
| Price, LA | 1 |
| Carrera Boadella, A | 1 |
| Pla Illa, RP | 1 |
| Alford, CA | 1 |
| Stagno, S | 1 |
| Reynolds, DW | 1 |
| Pochedly, C | 1 |
| Malakhovskiĭ, VG | 1 |
2 reviews available for pyrimethamine and Central Nervous System Disease
| Article | Year |
|---|---|
Therapeutic strategies involving antimicrobial treatment of the central nervous system in large animals.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anticonvulsants; Blood-Brain Barrier; Cattle; | 1984 |
Congenital toxoplasmosis: clinical, laboratory, and therapeutic considerations, with special reference to subclinical disease.
Topics: Alabama; Central Nervous System Diseases; Cerebrospinal Fluid Proteins; Child, Preschool; Female; Hu | 1974 |
2 trials available for pyrimethamine and Central Nervous System Disease
| Article | Year |
|---|---|
Randomized clinical comparison of daunorubicin (NSC-82151) alone with a combination of daunorubicin, cytosine arabinoside (NSC-63878), 6-thioguanine (NSC-752), and pyrimethamine (NSC-3061) for the treatment of acute nonlymphocytic leukemia.
Topics: Acute Disease; Aged; Antineoplastic Agents; Bone Marrow; Central Nervous System Diseases; Cyclophosp | 1976 |
Comparison of two medications in central nervous system toxoplasmosis in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Central Nervous System Diseases; Clindamycin; Drug Combinations; | 1992 |
17 other studies available for pyrimethamine and Central Nervous System Disease
| Article | Year |
|---|---|
Suspect novel adverse drug reactions to trimethoprim-sulphonamide combinations in horses: a case series.
Topics: Animals; Anti-Bacterial Agents; Central Nervous System Diseases; Drug Overdose; Drug Therapy, Combin | 2011 |
[THE SYMPTOMS OF ACQUIRED AND CONGENITAL TOXOPLASMOSIS].
Topics: Central Nervous System Diseases; Eye Manifestations; Humans; Pyrimethamine; Toxoplasmosis; Toxoplasm | 1963 |
Toxoplasmosis. Problems in diagnosis and treatment.
Topics: Adolescent; Adult; Central Nervous System Diseases; Drug Therapy, Combination; Female; Hodgkin Disea | 1983 |
Favorable outcome of central nervous system toxoplasmosis occurring in a patient with untreated Hodgkin's disease.
Topics: Adult; Antineoplastic Agents; Central Nervous System Diseases; Drug Therapy, Combination; Hodgkin Di | 1980 |
Severe megaloblastic anemia complicating pyrimethamine therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Anemia, Megaloblastic; Central Nervous System Diseases | 1995 |
Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. The New England Regional Toxoplasma Working Group.
Topics: Antibodies, Protozoan; Central Nervous System Diseases; Follow-Up Studies; Humans; Immunoglobulin G; | 1994 |
[Diagnosis and therapy of neoplastic meningosis].
Topics: Acute Disease; Central Nervous System Diseases; Cytarabine; Humans; Injections, Spinal; Leukemia; Me | 1975 |
Congenital toxoplasmosis occurring in infants perinatally infected with human immunodeficiency virus 1.
Topics: Acquired Immunodeficiency Syndrome; Animals; Central Nervous System Diseases; Family Health; Female; | 1990 |
Central nervous system toxoplasmosis in AIDS patients: efficacy of an intermittent maintenance therapy.
Topics: Acquired Immunodeficiency Syndrome; Central Nervous System Diseases; Clindamycin; Drug Combinations; | 1990 |
Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome. Efficacy of long-term continuous therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Central Nervous System Diseases; Drug Therapy, Combinatio | 1988 |
Toxoplasmosis of the central nervous system.
Topics: Adult; Central Nervous System Diseases; Cerebellum; Encephalitis; Female; Humans; Pyrimethamine; Sul | 1987 |
Role of clindamycin in the treatment of central nervous system toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Central Nervous System Diseases; Clindamycin; Drug Therap | 1987 |
Pyrimethamine in central-nervous-system leukaemia.
Topics: Adult; Central Nervous System Diseases; Humans; Leukemia; Male; Pyrimethamine | 1973 |
Pyrimethamine in central-nervous-system leukaemia.
Topics: Central Nervous System Diseases; Child; Humans; Leukemia; Pyrimethamine | 1973 |
Letter: Pyrimethamine in central-nervous-system leukaemia.
Topics: Adult; Central Nervous System Diseases; Child; Humans; Leukemia; Pyrimethamine; Remission, Spontaneo | 1973 |
Management of CNS leukemia in childhood. An outline of current concepts.
Topics: Central Nervous System Diseases; Child; Child, Preschool; Cytarabine; Humans; Leukemia; Meninges; Me | 1972 |
[The prenatal influence of chloridin and vitamin A on the behavior of the progeny of rats].
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Central Nervous System Diseases; Female; Hum | 1971 |