pyrimethamine has been researched along with Burkitt Lymphoma in 8 studies
Maloprim: contains above 2 cpds
Burkitt Lymphoma: A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "By this procedure a subline of Burkitt's lymphoma cells (RAJI) was made 290-fold resistant (RAJI/MTX-R), T-cell leukemia cells (CCRF-CEM) were obtained 210-fold resistant (CEM/MTX-R), and 3 MTX-resistant human osteosarcoma lines were selected: TE-85/MTX-R (19-fold resistant; relative to wild-type); MG-63/MTX-R (8-fold resistant); and SAOS-2/MTX-R (200-fold resistant)." | 5.27 | Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate. ( Diddens, H; Jackson, RC; Niethammer, D, 1983) |
| "By this procedure a subline of Burkitt's lymphoma cells (RAJI) was made 290-fold resistant (RAJI/MTX-R), T-cell leukemia cells (CCRF-CEM) were obtained 210-fold resistant (CEM/MTX-R), and 3 MTX-resistant human osteosarcoma lines were selected: TE-85/MTX-R (19-fold resistant; relative to wild-type); MG-63/MTX-R (8-fold resistant); and SAOS-2/MTX-R (200-fold resistant)." | 1.27 | Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate. ( Diddens, H; Jackson, RC; Niethammer, D, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diddens, H | 1 |
| Niethammer, D | 1 |
| Jackson, RC | 1 |
| Sadoff, L | 2 |
| MacGregor, GA | 1 |
| Hutt, MS | 1 |
| Burkitt, DP | 1 |
| Williams, EH | 1 |
| Bruce-Chwatt, LJ | 1 |
8 other studies available for pyrimethamine and Burkitt Lymphoma
| Article | Year |
|---|---|
Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
Topics: Antineoplastic Agents; Biological Transport; Burkitt Lymphoma; Cell Line; Drug Resistance; Folic Aci | 1983 |
Etiology of Burkitt's lymphoma.
Topics: Burkitt Lymphoma; Humans; Immunosuppressive Agents; Lymphoma, Large B-Cell, Diffuse; Male; Middle Ag | 1972 |
Aetiology of Burkitt's lymphoma.
Topics: Burkitt Lymphoma; Humans; Immunosuppression Therapy; Pyrimethamine | 1973 |
Aetiology of Burkitt's lymphoma.
Topics: Burkitt Lymphoma; Humans; Pyrimethamine; Uganda | 1973 |
Aetiology of Burkitt's lymphoma.
Topics: Burkitt Lymphoma; Humans; Pyrimethamine; Uganda | 1973 |
Letter: Antimalarial drugs and Burkitt's lymphoma.
Topics: Antimalarials; Burkitt Lymphoma; Child; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Pre | 1973 |
Letter: Antimalarial drugs and Burkitt's lymphoma.
Topics: Africa; Burkitt Lymphoma; Humans; Pyrimethamine; Rural Population | 1974 |
Letter: Antimalarial drugs and Burkitt's lymphoma.
Topics: Adult; Africa; Animals; Burkitt Lymphoma; Carcinogens; Child; Chloroquine; Humans; Plant Extracts; P | 1974 |