pyrimethamine and Brain Diseases
pyrimethamine has been researched along with Brain Diseases in 34 studies
Maloprim: contains above 2 cpds
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Cerebral toxoplasmosis related to AIDS was treated with a combination regimen of pyrimethamine, clindamycin, and spiramycin, and in a second trial with a combination of pyrimethamine and clindamycin." | 7.68 | Role of clindamycin in the treatment of acute toxoplasmosis of the central nervous system. ( Pohle, HD; Ruf, B, 1991) |
"A substantial reduction of brain cyst numbers could be obtained through a six week therapy with SDDS-pyrimethamine combination or a high titer anti-Toxoplasma serum." | 7.65 | The effect of chemo-immunotherapy with SDDS, pyrimethamine and anti-toxoplasma serum on toxoplasma gondii cysts in latent infected NMRI mice. ( Adusu, E; Masihi, KN; Tischer, I; Werner, H, 1977) |
"Cerebral toxoplasmosis related to AIDS was treated with a combination regimen of pyrimethamine, clindamycin, and spiramycin, and in a second trial with a combination of pyrimethamine and clindamycin." | 3.68 | Role of clindamycin in the treatment of acute toxoplasmosis of the central nervous system. ( Pohle, HD; Ruf, B, 1991) |
"A substantial reduction of brain cyst numbers could be obtained through a six week therapy with SDDS-pyrimethamine combination or a high titer anti-Toxoplasma serum." | 3.65 | The effect of chemo-immunotherapy with SDDS, pyrimethamine and anti-toxoplasma serum on toxoplasma gondii cysts in latent infected NMRI mice. ( Adusu, E; Masihi, KN; Tischer, I; Werner, H, 1977) |
"The activity of the macrolide antibiotic clarithromycin was examined alone or in combination with other drugs for the treatment of acute or chronic infections with Toxoplasma gondii in mice." | 1.28 | Activity of clarithromycin alone or in combination with other drugs for treatment of murine toxoplasmosis. ( Araujo, FG; Lin, T; Prokocimer, P; Remington, JS, 1992) |
"No relapse was observed in those receiving P/S, but 40% of those treated with P/C relapsed." | 1.28 | [Encephalic toxoplasmosis in patients with the acquired immunodeficiency syndrome. A clinico-radiological study and the therapeutic results in 78 cases]. ( Alvarez, R; Gatell, JM; González-Clemente, JM; Graus, F; Guelar, A; Jiménez de Anta, MT; Mallolas, J; Mercader, JM; Miró, JM; Pedrol, E, 1990) |
" Reappraisal of quinine therapy has led to important modifications in dosage recommendations and recognition of a major complication of severe malaria associated with its use--hypoglycaemia." | 1.27 | Management of Plasmodium falciparum malaria. ( Phillips, RE, 1984) |
"Treatment with sulfadiazine, pyrimethamine, and steroids brought about a prompt resolution." | 1.26 | Acute acquired toxoplasmosis. ( Reese, LT; Shafer, DM; Zweifach, P, 1981) |
Research
Studies (34)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 23 (67.65) | 18.7374 |
1990's | 10 (29.41) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (2.94) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Chuang, YC | 1 |
Chen, JY | 1 |
Ji, DD | 1 |
Su, PH | 1 |
GOLIAS-MAKOWSKA, A | 1 |
DUC, G | 1 |
JUNGO, O | 1 |
GUGLER, E | 1 |
Phillips, RE | 1 |
Reese, LT | 1 |
Shafer, DM | 1 |
Zweifach, P | 1 |
Santucci, A | 1 |
Aguglia, F | 1 |
Federico, M | 1 |
De Mattia, G | 1 |
Montero, A | 1 |
Cohen, JE | 1 |
Martínez, DP | 1 |
Giovannoni, AG | 1 |
Foulon, W | 1 |
Villena, I | 1 |
Stray-Pedersen, B | 1 |
Decoster, A | 1 |
Lappalainen, M | 1 |
Pinon, JM | 1 |
Jenum, PA | 1 |
Hedman, K | 1 |
Naessens, A | 1 |
Schlenska, GK | 1 |
Werner, H | 1 |
Masihi, KN | 1 |
Tischer, I | 1 |
Adusu, E | 1 |
Yoeli, M | 1 |
Masson, R | 1 |
Fière, D | 1 |
Lahnèche, B | 1 |
Cordat, C | 1 |
Berger, F | 1 |
Revol, L | 1 |
Araujo, FG | 1 |
Prokocimer, P | 1 |
Lin, T | 1 |
Remington, JS | 1 |
Clotet, B | 1 |
Sirera, G | 1 |
Romeu, J | 1 |
Gimeno, JM | 1 |
Jou, A | 1 |
Condom, MJ | 1 |
Tor, J | 1 |
Foz, M | 1 |
Díaz Benito, JA | 1 |
Rodríguez García, JC | 1 |
Piñeiro Gómez-Durán, L | 1 |
Ruf, B | 1 |
Pohle, HD | 1 |
González-Clemente, JM | 1 |
Miró, JM | 1 |
Pedrol, E | 1 |
Alvarez, R | 1 |
Gatell, JM | 1 |
Mallolas, J | 1 |
Graus, F | 1 |
Mercader, JM | 1 |
Guelar, A | 1 |
Jiménez de Anta, MT | 1 |
Chakroun, M | 1 |
Meyohas, MC | 1 |
Pelosse, B | 1 |
Zazoun, L | 1 |
Vacherot, B | 1 |
Derouin, F | 1 |
Leport, C | 3 |
Boudes, P | 1 |
Zittoun, J | 1 |
Sobel, A | 1 |
Bhatti, N | 1 |
Larson, E | 1 |
Kassirer, JP | 1 |
Kopelman, RI | 1 |
Altés, J | 1 |
Salas, A | 1 |
Ricart, C | 1 |
Villalonga, C | 1 |
Riera, M | 1 |
Casquero, P | 1 |
Ventura, MG | 1 |
Wybran, J | 1 |
Farber, CM | 1 |
Bastuji-Garin, S | 1 |
Perronne, C | 1 |
Salmon, D | 1 |
Marche, C | 1 |
Briçaire, F | 1 |
Vilde, JL | 2 |
Bonaventura, I | 1 |
Romero, F | 1 |
Ortega, A | 1 |
Navarro, C | 1 |
Juste, C | 1 |
Codina Puiggrós, A | 1 |
Rolston, KV | 1 |
Katlama, C | 1 |
Regnier, B | 1 |
Mathéron, S | 1 |
Saimot, AG | 1 |
Navia, BA | 1 |
Petito, CK | 1 |
Gold, JW | 1 |
Cho, ES | 1 |
Jordan, BD | 1 |
Price, RW | 1 |
Diop Mar, I | 1 |
Sow, A | 1 |
Gyr, K | 1 |
Speck, B | 1 |
Ritz, R | 1 |
Cornu, P | 1 |
Buckner, CD | 1 |
Doutlik, S | 1 |
Kouba, K | 1 |
Geils, GF | 1 |
Scott, CW | 1 |
Baugh, CM | 1 |
Blount, RE | 1 |
Verdrager, J | 1 |
Reviews
1 review available for pyrimethamine and Brain Diseases
Article | Year |
---|---|
[Empirical anti-toxoplasma therapy in cerebral AIDS and Chagas disease. Presentation of 2 cases, review of the literature and proposal of an algorithm].
Topics: Adult; AIDS-Related Opportunistic Infections; Algorithms; Antiprotozoal Agents; Brain Diseases; Chag | 1998 |
Other Studies
33 other studies available for pyrimethamine and Brain Diseases
Article | Year |
---|---|
Congenital toxoplasmosis in a neonate with significant neurologic manifestations.
Topics: Adult; Antibodies, Protozoan; Antiprotozoal Agents; Brain Diseases; Female; Fetal Growth Retardation | 2012 |
[2 CASES OF CONGENITAL TOXOPLASMOSIS].
Topics: Adrenal Cortex Hormones; Brain Diseases; Calcinosis; Child; Chlortetracycline; Drug Therapy; Erythro | 1964 |
[BILATERAL FACIAL PARALYSIS AND ACQUIRED TOXOPLASMOSIS IN A 4-YEAR-OLD CHILD].
Topics: Brain Diseases; Child; Drug Therapy; Facial Paralysis; Humans; Paralysis; Pyrimethamine; Sulfisoxazo | 1964 |
Management of Plasmodium falciparum malaria.
Topics: Amodiaquine; Anemia; Antimalarials; Brain Diseases; Chloroquine; Drug Resistance; Female; Humans; Hy | 1984 |
Acute acquired toxoplasmosis.
Topics: Brain Diseases; Drug Therapy, Combination; Endophthalmitis; Female; Humans; Middle Aged; Pyrimethami | 1981 |
[Neuroendocrine syndromes with toxoplasmic origin: clinical and therapeutic considerations].
Topics: Adult; Brain Diseases; Child; Chloroquine; Female; Fenfluramine; Humans; Pyrimethamine; Sulfamethoxy | 1980 |
Treatment of toxoplasmosis during pregnancy: a multicenter study of impact on fetal transmission and children's sequelae at age 1 year.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Brain Diseases; Calcinosis; Choroid Diseases; | 1999 |
[Symptomatology, diagnosis, and treatment of nervous tissue affecting toxoplasmosis in adult (author's transl)].
Topics: Adult; Brain Diseases; Diagnosis, Differential; Female; Humans; Immunosuppression Therapy; Male; Mul | 1978 |
The effect of chemo-immunotherapy with SDDS, pyrimethamine and anti-toxoplasma serum on toxoplasma gondii cysts in latent infected NMRI mice.
Topics: Animals; Brain Diseases; Cysts; Dapsone; Female; Immunotherapy; Mice; Mice, Inbred Strains; Pyrimeth | 1977 |
Chadwick lecture. Cerebral malaria--the quest for suitable experimental models in parasitic diseases of man.
Topics: Africa; Animals; Brain; Brain Diseases; Disease Models, Animal; Drug Resistance; Haplorhini; Humans; | 1976 |
[Encephalic pseudotumoral toxoplasmosis in the course of blood diseases].
Topics: Brain; Brain Diseases; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Immunosuppression | 1975 |
Activity of clarithromycin alone or in combination with other drugs for treatment of murine toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Animals; Brain Diseases; Chronic Disease; Clarith | 1992 |
Twice-weekly dapsone-pyrimethamine for preventing PCP and cerebral toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Dapsone; Drug Administration Schedule; Drug Ther | 1991 |
[Cerebral toxoplasmosis as a cause of treatable dementia in an aged patient].
Topics: Acquired Immunodeficiency Syndrome; Aged; Brain; Brain Diseases; Dementia; Humans; Male; Pyrimethami | 1991 |
Role of clindamycin in the treatment of acute toxoplasmosis of the central nervous system.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Brain Diseases; Clindamycin; Drug Therapy, Combin | 1991 |
[Encephalic toxoplasmosis in patients with the acquired immunodeficiency syndrome. A clinico-radiological study and the therapeutic results in 78 cases].
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Biopsy; Brain; Brain Diseases; Clindamycin; Drug | 1990 |
[Ocular toxoplasmosis in AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Diseases; Humans; Male; Middle Aged; Opportunistic | 1990 |
[Acute pancytopenia induced by pyrimethamine during treatment of cerebral toxoplasmosis associated with AIDS. Role of dihydrofolate reductase inhibitors].
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; Brain Diseases; Folic Acid Antagonists; Fo | 1990 |
Low-dose alternate-day pyrimethamine for maintenance therapy in cerebral toxoplasmosis complicating AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Brain Diseases; Drug Administratio | 1990 |
Interpreting negative test results.
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Diseases; Diagnosis, Differential; False Negative R | 1989 |
[Cerebral toxoplasmosis in patients with AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Diseases; Drug Evaluation; Drug Therapy, Combinatio | 1989 |
Sulfadiazine revisited.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Brain Diseases; Crystallization; D | 1989 |
An open study of the pyrimethamine-clindamycin combination in AIDS patients with brain toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Clindamycin; Drug Therapy, Combination; Humans; | 1989 |
[Cerebral toxoplasmosis in the acquired immunodeficiency syndrome. Study of the clinical, radiological, and pathological findings in 10 cases].
Topics: Acquired Immunodeficiency Syndrome; Brain Abscess; Brain Diseases; Humans; Opportunistic Infections; | 1988 |
Clindamycin in cerebral toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Clindamycin; Drug Therapy, Combination; Humans; | 1988 |
[Cerebral toxoplasmosis in immunosuppressed patients: diagnosis and treatment].
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Diseases; Drug Combinations; Female; Humans; Leucom | 1987 |
Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopsy; Brain Diseases; Central Nervous System; Clindamyc | 1986 |
[Treatment of cerebral malaria with a fansidar-hydergine combination].
Topics: Adolescent; Adult; Antimalarials; Brain Diseases; Child; Child, Preschool; Coma; Drug Combinations; | 1973 |
[Cerebral tropical malaria with blackwater fever. A current diagnostic and therapeutic problem].
Topics: Acute Kidney Injury; Adult; Blackwater Fever; Brain Diseases; Chloroquine; Disseminated Intravascula | 1974 |
[The neurologic manifestations of toxoplasmosis].
Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; | 1974 |
Treatment of meningeal leukemia with pyrimethamine.
Topics: Adult; Brain Diseases; Folic Acid; Hallucinations; Humans; Leukemia, Myeloid, Acute; Male; Meninges; | 1971 |
Management of chloroquine resistant falciparum malaria.
Topics: Adult; Brain Diseases; Chloroquine; Dapsone; Dexamethasone; Drug Resistance, Microbial; Edema; Human | 1967 |
Cerebral malaria following blood transfusion.
Topics: Adult; Brain Diseases; Chloroquine; Communicable Disease Control; Disease Reservoirs; Humans; Malari | 1969 |