Page last updated: 2024-11-03

pyrimethamine and Birth Weight

pyrimethamine has been researched along with Birth Weight in 42 studies

Maloprim: contains above 2 cpds

Birth Weight: The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Adequate prevention regimen with monthly sulfadoxine-pyrimethamine given to all pregnant women has been proved to reduce the risk of LBW in malaria endemic areas."9.69Effects of maternal antenatal treatment with two doses of azithromycin added to monthly sulfadoxine-pyrimethamine for the prevention of low birth weight in Burkina Faso: an open-label randomized controlled trial. ( Derra, K; Donnen, P; Dramaix, M; Kaboré, B; Lingani, M; Robert, A; Rouamba, T; Samadoulougou, S; Sanou, M; Somé, G; Sorgho, H; Tahita, MC; Tinto, H; Valéa, I; Zango, SH, 2023)
"Trials of intermittent preventive treatment (IPTp) of malaria in pregnant women that compared dihydroartemisinin-piperaquine with the standard of care, sulfadoxine-pyrimethamine, showed dihydroartemisinin-piperaquine was superior at preventing malaria infection, but not at improving birthweight."9.34Overall, anti-malarial, and non-malarial effect of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine on birthweight: a mediation analysis. ( Chico, RM; Desai, M; Dorsey, G; Glymour, MM; Gosling, R; Gutman, J; Kajubi, R; Kakuru, A; Kamya, MR; Kuile, FOT; L'Ianziva, A; Rerolle, F; Roh, ME; Shiboski, S, 2020)
"The World Health Organization advocates 2-3 doses of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment of malaria (SP IPTp)."9.12Inferiority of single-dose sulfadoxine-pyrimethamine intermittent preventive therapy for malaria during pregnancy among HIV-positive Zambian women. ( Chalwe, V; Champo, D; Chilengi, R; Gill, CJ; Hamer, DH; Macleod, WB; Mukwamataba, D; Mwanakasale, V; Mwananyanda, L; Thea, DM, 2007)
"Intermittent preventive treatment with sulphadoxine-pyrimethamine (IPT-SP) is currently the recommended regimen for prevention of malaria in pregnancy in endemic areas."9.12Intermittent preventive treatment with sulphadoxine-pyrimethamine is effective in preventing maternal and placental malaria in Ibadan, south-western Nigeria. ( Fadero, FF; Falade, CO; Hamer, DH; Mokuolu, OA; Salako, LA; Yusuf, BO, 2007)
"This study highlights low adherence to the new 3-dose regimen of sulfadoxine-pyrimethamine-based intermittent preventive treatment in the Cotonou health zone II and III, but it reflects its potential to contribute to the reduction of the risk of low birth weight."7.91[Sulfadoxine-pyrimethamine-based intermittent preventive treatment in pregnant women and its effect on birth weight: application of 3-dosing regimen in the urban area of South Benin in 2017]. ( Ayivi-Vinz, G; Azandjèmé, C; Biaou, COA; Glèlè-Ahanhanzo, Y; Kpozehouen, A; Ouro-Koura, AR, 2019)
"Birth weight data from three regions in Democratic Republic of Congo with varying degrees of sulfadoxine-pyrimethamine (SP) resistance (1."7.78Sulfadoxine-pyrimethamine resistance and intermittent preventive treatment during pregnancy: a retrospective analysis of birth weight data in the Democratic Republic of Congo (DRC). ( D'Alessandro, U; Dramaix, MW; Likwela, JL; Lokwa, BL; Meuris, S, 2012)
"To evaluate the impact of a 2-year programme for community-based delivery of sulfadoxine-pyrimethamine (SP) on intermittent preventive treatment during pregnancy coverage, antenatal clinic attendance and pregnancy outcome."7.75Community-based distribution of sulfadoxine-pyrimethamine for intermittent preventive treatment of malaria during pregnancy improved coverage but reduced antenatal attendance in southern Malawi. ( Brabin, BJ; D'Alessandro, U; Gies, S; Kalanda, G; Kazembe, PN; Msyamboza, KP; Savage, EJ, 2009)
"To monitor the effectiveness of intermittent preventive treatment (IPT) with sulphadoxine-pyrimethamine (SP) for the control of malaria in pregnancy at delivery in the Provincial Hospital in Kisumu, Kenya, and to assess the effect of IPT in participants in a cohort study."7.72Effectiveness of intermittent preventive treatment with sulphadoxine-pyrimethamine for control of malaria in pregnancy in western Kenya: a hospital-based study. ( Ayisi, JG; Kager, PA; Misore, AO; Nahlen, BL; Odondi, JO; Otieno, JA; Rosen, DH; Steketee, RW; ter Kuile, FO; van Eijk, AM, 2004)
"The prevalence of infection with malarial parasites and the incidence of anaemia and delivery of infants with low birthweight (LBW) were investigated in 575 Malawian mothers who received one, two or three doses of sulfadoxine-pyrimethamine (SP) during pregnancy."7.70An evaluation of the effects of intermittent sulfadoxine-pyrimethamine treatment in pregnancy on parasite clearance and risk of low birthweight in rural Malawi. ( Brabin, BJ; Broadhead, RL; Chimsuku, L; Kazembe, P; Russell, WB; Verhoeff, FH, 1998)
"Low birth weight was defined as weight < 2500 g irrespective of the gestational age of the foetus, while normal birth weight was between 2500 g to < 4000 g and macrosomia was =  > 4000 g."5.72Predicting the effect of sulfadoxine-pyrimethamine uptake by pregnant women on birth weight using a generalized ordered partial proportional odds model. ( Afagbedzi, S; Guure, C, 2022)
"Adequate prevention regimen with monthly sulfadoxine-pyrimethamine given to all pregnant women has been proved to reduce the risk of LBW in malaria endemic areas."5.69Effects of maternal antenatal treatment with two doses of azithromycin added to monthly sulfadoxine-pyrimethamine for the prevention of low birth weight in Burkina Faso: an open-label randomized controlled trial. ( Derra, K; Donnen, P; Dramaix, M; Kaboré, B; Lingani, M; Robert, A; Rouamba, T; Samadoulougou, S; Sanou, M; Somé, G; Sorgho, H; Tahita, MC; Tinto, H; Valéa, I; Zango, SH, 2023)
" Sulfadoxine-pyrimethamine (SP), given for intermittent preventive therapy of malaria in pregnancy (IPTp), is one of few existing interventions that improves outcomes of both mother and baby despite widespread SP-resistant malaria."5.51The positive effect of malaria IPTp-SP on birthweight is mediated by gestational weight gain but modifiable by maternal carriage of enteric pathogens. ( Bartelt, LA; Carroll, I; Chinkhumba, J; Gutman, JR; Itoh, M; Juliano, JJ; Kayange, M; Mathanga, DP; McQuade, ETR; Meshnick, SR; Mzembe, E; Operario, DJ; Puerto-Meredith, SM; Waltmann, A, 2022)
"Sulfadoxine-pyrimethamine (SP) is used as intermittent preventive therapy in pregnancy (IPTp) for malaria in sub-Saharan Africa."5.34Interactions Between Antenatal Sulfadoxine-Pyrimethamine, Drug-Resistant Plasmodium falciparum Parasites, and Delivery Outcomes in Malawi. ( Freedman, B; Kalilani-Phiri, L; Khairallah, C; Levitt, B; Madanitsa, M; Meshnick, SR; Mwapasa, V; Taylor, SM; Ter Kuile, FO; Thwai, KL, 2020)
"Trials of intermittent preventive treatment (IPTp) of malaria in pregnant women that compared dihydroartemisinin-piperaquine with the standard of care, sulfadoxine-pyrimethamine, showed dihydroartemisinin-piperaquine was superior at preventing malaria infection, but not at improving birthweight."5.34Overall, anti-malarial, and non-malarial effect of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine on birthweight: a mediation analysis. ( Chico, RM; Desai, M; Dorsey, G; Glymour, MM; Gosling, R; Gutman, J; Kajubi, R; Kakuru, A; Kamya, MR; Kuile, FOT; L'Ianziva, A; Rerolle, F; Roh, ME; Shiboski, S, 2020)
"Intermittent preventive treatment in pregnancy (IPTp) with azithromycin and monthly sulfadoxine-pyrimethamine increased the mean child weight, mid-upper arm and head circumference at four weeks of age in a rural low-income setting."5.30The impact of maternal antenatal treatment with two doses of azithromycin and monthly sulphadoxine-pyrimethamine on child weight, mid-upper arm circumference and head circumference: A randomized controlled trial. ( Ashorn, P; Ashorn, U; Cheung, YB; Hallamaa, L; Kulmala, T; Luntamo, M; Mangani, C, 2019)
"The efficacy of intermittent preventive treatment for malaria with sulfadoxine-pyrimethamine (IPTp-SP) in pregnancy is threatened in parts of Africa by the emergence and spread of resistance to SP."5.20A Non-Inferiority, Individually Randomized Trial of Intermittent Screening and Treatment versus Intermittent Preventive Treatment in the Control of Malaria in Pregnancy. ( Abubakar, I; Akor, F; Awine, T; Bationo, R; Bojang, K; Cairns, M; Chandramohan, D; Coulibaly, SO; Dabira, E; Djimdé, M; Doumbo, O; Greenwood, B; Guirou, E; Hodgson, A; Kayentao, K; Magnussen, P; Meshnick, S; Milligan, P; Mohammed, K; Njie, F; Oduro, A; Ordi, J; Quaye, S; Soulama, A; Tagbor, H; Taylor, S; ter Kuile, F; Williams, J; Woukeu, A, 2015)
"To examine the potential to reduce foetal and neonatal growth faltering through intermittent preventive treatment in pregnancy (IPTp) of malaria and reproductive tract infections with monthly sulphadoxine-pyrimethamine (SP), alone or with two doses of azithromycin."5.17The effect of antenatal monthly sulphadoxine-pyrimethamine, alone or with azithromycin, on foetal and neonatal growth faltering in Malawi: a randomised controlled trial. ( Ashorn, P; Cheung, YB; Kulmala, T; Luntamo, M; Maleta, K, 2013)
"To investigate the consequences of intermittent preventive treatment (IPTp) timing on birth weight, we pooled data from two studies conducted in Benin between 2005 and 2010: a prospective cohort of 1037 pregnant women and a randomised trial comparing sulfadoxine-pyrimethamine (SP) to mefloquine in 1601 women."5.16Consequences of gestational malaria on birth weight: finding the best timeframe for intermittent preventive treatment administration. ( Borgella, S; Briand, V; Cot, M; Deloron, P; Fievet, N; Huynh, BT; Massougbodji, A, 2012)
"Few studies have documented the effectiveness in west Africa of intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine (SP) in pregnancy."5.12A comparison of sulfadoxine-pyrimethamine with chloroquine and pyrimethamine for prevention of malaria in pregnant Nigerian women. ( Madaki, JK; Sagay, AS; Thacher, TD; Tukur, IU, 2007)
"Intermittent preventive treatment with sulphadoxine-pyrimethamine (IPT-SP) is currently the recommended regimen for prevention of malaria in pregnancy in endemic areas."5.12Intermittent preventive treatment with sulphadoxine-pyrimethamine is effective in preventing maternal and placental malaria in Ibadan, south-western Nigeria. ( Fadero, FF; Falade, CO; Hamer, DH; Mokuolu, OA; Salako, LA; Yusuf, BO, 2007)
"The World Health Organization advocates 2-3 doses of sulfadoxine-pyrimethamine (SP) for intermittent preventive treatment of malaria (SP IPTp)."5.12Inferiority of single-dose sulfadoxine-pyrimethamine intermittent preventive therapy for malaria during pregnancy among HIV-positive Zambian women. ( Chalwe, V; Champo, D; Chilengi, R; Gill, CJ; Hamer, DH; Macleod, WB; Mukwamataba, D; Mwanakasale, V; Mwananyanda, L; Thea, DM, 2007)
"In Mali, IPT with SP appears more efficacious than weekly chloroquine chemoprophylaxis in preventing malaria during pregnancy."5.11Comparison of intermittent preventive treatment with chemoprophylaxis for the prevention of malaria during pregnancy in Mali. ( Coulibaly, D; Doumbo, O; Doumtabe, D; Kayentao, K; Keita, AS; Kodio, M; Maiga, B; Maiga, H; Mungai, M; Newman, RD; Ongoiba, A; Parise, ME, 2005)
"Intermittent preventive therapy during pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended in areas of moderate to high malaria transmission intensity."4.31Peripheral and Placental Prevalence of Sulfadoxine-Pyrimethamine Resistance Markers in Plasmodium falciparum among Pregnant Women in Southern Province, Rwanda. ( Abram, A; Alruwaili, M; Eckert, E; Gutman, JR; Mbituyumuremyi, A; Munguti, K; Murindahabi, M; Piercefield, E; Sethi, R; Sullivan, DJ; Umulisa, N; Uwimana, A, 2023)
"Mutations in the Plasmodium falciparum genes Pfdhfr and Pfdhps, particularly the sextuple mutant haplotype threatens the antimalarial effectiveness of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment during pregnancy (IPTp)."4.02Reduced Birth Weight Caused by Sextuple Drug-Resistant Plasmodium falciparum Infection in Early Second Trimester. ( Alifrangis, M; Bygbjerg, IC; Hansson, H; Jensen, RW; Lusingu, JPA; Minja, DTR; Moeller, SL; Msemo, OA; Nag, S; Schmiegelow, C; Theander, TG; Yde, AM, 2021)
"A cross-sectional study was conducted of 426 pregnant mothers on IPTp with sulphadoxine-pyrimethamine against malaria who presented in labor, at National Hospital Abuja, Nigeria between January and June 2017."3.96The efficacy of intermittent preventive therapy in the eradication of peripheral and placental parasitemia in a malaria-endemic environment, as seen in a tertiary hospital in Abuja, Nigeria. ( Agboghoroma, CO; Iregbu, KC; Umemmuo, MU, 2020)
"Despite the clinically proven advantages of intermittent preventive treatment of malaria in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP), utilisation has been low in many African countries."3.91High uptake of Intermittent Preventive Treatment of malaria in pregnancy is associated with improved birth weight among pregnant women in Ghana. ( Anang, AK; Asare, GQ; Coleman, N; Cot, M; Cottrell, G; Deloron, P; Escriou, G; Fobil, J; Houze, P; Kusi, KA; Laar, A; Ndam, NT; Ofori, MF; Quakyi, I; Tornyigah, B, 2019)
"This study highlights low adherence to the new 3-dose regimen of sulfadoxine-pyrimethamine-based intermittent preventive treatment in the Cotonou health zone II and III, but it reflects its potential to contribute to the reduction of the risk of low birth weight."3.91[Sulfadoxine-pyrimethamine-based intermittent preventive treatment in pregnant women and its effect on birth weight: application of 3-dosing regimen in the urban area of South Benin in 2017]. ( Ayivi-Vinz, G; Azandjèmé, C; Biaou, COA; Glèlè-Ahanhanzo, Y; Kpozehouen, A; Ouro-Koura, AR, 2019)
"Six years after the implementation of intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) in Gabon, its impact on placental malaria and pregnancy outcomes remains unknown."3.83Decrease of microscopic Plasmodium falciparum infection prevalence during pregnancy following IPTp-SP implementation in urban cities of Gabon. ( Ambounda, N; Bouyou-Akotet, MK; Kendjo, E; Kombila, M; Mawili-Mboumba, DP; Moutandou Chiesa, S; Tshibola Mbuyi, ML; Tsoumbou-Bakana, G; Zong, J, 2016)
"Birth weight data from three regions in Democratic Republic of Congo with varying degrees of sulfadoxine-pyrimethamine (SP) resistance (1."3.78Sulfadoxine-pyrimethamine resistance and intermittent preventive treatment during pregnancy: a retrospective analysis of birth weight data in the Democratic Republic of Congo (DRC). ( D'Alessandro, U; Dramaix, MW; Likwela, JL; Lokwa, BL; Meuris, S, 2012)
"To evaluate the impact of a 2-year programme for community-based delivery of sulfadoxine-pyrimethamine (SP) on intermittent preventive treatment during pregnancy coverage, antenatal clinic attendance and pregnancy outcome."3.75Community-based distribution of sulfadoxine-pyrimethamine for intermittent preventive treatment of malaria during pregnancy improved coverage but reduced antenatal attendance in southern Malawi. ( Brabin, BJ; D'Alessandro, U; Gies, S; Kalanda, G; Kazembe, PN; Msyamboza, KP; Savage, EJ, 2009)
"Intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) has been adopted as policy by many countries in sub-Saharan Africa."3.74Decline of placental malaria in southern Ghana after the implementation of intermittent preventive treatment in pregnancy. ( Acquah, PA; Bedu-Addo, G; Bienzle, U; Eggelte, TA; Holmberg, V; Hommerich, L; Mockenhaupt, FP; von Oertzen, C, 2007)
"To monitor the effectiveness of intermittent preventive treatment (IPT) with sulphadoxine-pyrimethamine (SP) for the control of malaria in pregnancy at delivery in the Provincial Hospital in Kisumu, Kenya, and to assess the effect of IPT in participants in a cohort study."3.72Effectiveness of intermittent preventive treatment with sulphadoxine-pyrimethamine for control of malaria in pregnancy in western Kenya: a hospital-based study. ( Ayisi, JG; Kager, PA; Misore, AO; Nahlen, BL; Odondi, JO; Otieno, JA; Rosen, DH; Steketee, RW; ter Kuile, FO; van Eijk, AM, 2004)
"The prevalence of infection with malarial parasites and the incidence of anaemia and delivery of infants with low birthweight (LBW) were investigated in 575 Malawian mothers who received one, two or three doses of sulfadoxine-pyrimethamine (SP) during pregnancy."3.70An evaluation of the effects of intermittent sulfadoxine-pyrimethamine treatment in pregnancy on parasite clearance and risk of low birthweight in rural Malawi. ( Brabin, BJ; Broadhead, RL; Chimsuku, L; Kazembe, P; Russell, WB; Verhoeff, FH, 1998)
" However, the optimal dosing regimen in settings in which human immunodeficiency virus (HIV) is highly prevalent among pregnant women remains controversial."2.73Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-seropositive pregnant Zambian women. ( Chalwe, V; Champo, D; Chilengi, R; Gill, CJ; Hamer, DH; Macleod, WB; Mubikayi, L; Mukwamataba, D; Mulele, CK; Mulenga, M; Mwanakasale, V; Mwananyanda, L; Thea, DM, 2007)
"Low birth weight was defined as weight < 2500 g irrespective of the gestational age of the foetus, while normal birth weight was between 2500 g to < 4000 g and macrosomia was =  > 4000 g."1.72Predicting the effect of sulfadoxine-pyrimethamine uptake by pregnant women on birth weight using a generalized ordered partial proportional odds model. ( Afagbedzi, S; Guure, C, 2022)
"007) and dosage (p = 0."1.72Intermittent preventive treatment with Sulphadoxine-Pyrimethamine (IPTp-SP) is associated with protection against sub-microscopic P. falciparum infection in pregnant women during the low transmission dry season in southwestern Cameroon: A Semi - longitudi ( Achidi, EA; Amambua-Ngwa, A; Anchang-Kimbi, JK; Apinjoh, TO; Chi, HF; Dionne-Odom, J; Kwi, PN; Mayaba, JM; Moyeh, MN; Ntui, VN; Tangi, LN; Tita, ATN; Titanji, VPK; Toussi, CT, 2022)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.76)18.7374
1990's2 (4.76)18.2507
2000's10 (23.81)29.6817
2010's15 (35.71)24.3611
2020's13 (30.95)2.80

Authors

AuthorsStudies
Menendez, C2
Todd, J1
Alonso, PL1
Lulat, S1
Francis, N1
Greenwood, BM1
Waltmann, A1
McQuade, ETR1
Chinkhumba, J1
Operario, DJ1
Mzembe, E1
Itoh, M1
Kayange, M1
Puerto-Meredith, SM1
Mathanga, DP1
Juliano, JJ1
Carroll, I1
Bartelt, LA1
Gutman, JR3
Meshnick, SR3
Guure, C1
Afagbedzi, S1
Apinjoh, TO1
Ntui, VN1
Chi, HF1
Moyeh, MN1
Toussi, CT1
Mayaba, JM1
Tangi, LN1
Kwi, PN1
Anchang-Kimbi, JK1
Dionne-Odom, J1
Tita, ATN1
Achidi, EA1
Amambua-Ngwa, A1
Titanji, VPK1
Ampofo, GD1
Osarfo, J1
Aberese-Ako, M1
Asem, L1
Komey, MN1
Mohammed, W1
Ofosu, AA1
Tagbor, H2
Crider, K1
Williams, J2
Qi, YP1
Gutman, J2
Yeung, L1
Mai, C1
Finkelstain, J1
Mehta, S1
Pons-Duran, C1
Moraleda, C1
Rogers, L1
Daniels, K1
Green, P1
Uwimana, A2
Sethi, R2
Murindahabi, M2
Ntirandeka, C1
Piercefield, E2
Umulisa, N2
Abram, A2
Eckert, E2
Munguti, K2
Sullivan, D1
Uyizeye, D1
Mbituyumuremyi, A2
Lingani, M1
Zango, SH1
Valéa, I1
Samadoulougou, S1
Somé, G1
Sanou, M1
Kaboré, B1
Rouamba, T1
Sorgho, H1
Tahita, MC1
Derra, K1
Dramaix, M1
Tinto, H1
Donnen, P1
Robert, A1
Alruwaili, M1
Sullivan, DJ1
Umemmuo, MU1
Agboghoroma, CO1
Iregbu, KC1
Quakyi, I1
Tornyigah, B1
Houze, P1
Kusi, KA1
Coleman, N1
Escriou, G1
Laar, A1
Cot, M2
Fobil, J1
Asare, GQ1
Deloron, P2
Anang, AK1
Cottrell, G1
Ofori, MF1
Ndam, NT1
Biaou, COA1
Kpozehouen, A1
Glèlè-Ahanhanzo, Y1
Ayivi-Vinz, G1
Ouro-Koura, AR1
Azandjèmé, C1
Taylor, SM2
Levitt, B1
Freedman, B1
Madanitsa, M1
Thwai, KL1
Kalilani-Phiri, L1
Khairallah, C1
Mwapasa, V1
Ter Kuile, FO3
Salman, S1
Davis, TME1
Moore, B1
Roh, ME1
Kuile, FOT1
Rerolle, F1
Glymour, MM1
Shiboski, S1
Gosling, R1
Kakuru, A1
Desai, M1
Kajubi, R1
L'Ianziva, A1
Kamya, MR1
Dorsey, G1
Chico, RM1
Hansson, H1
Minja, DTR1
Moeller, SL1
Lusingu, JPA1
Bygbjerg, IC1
Yde, AM1
Jensen, RW1
Nag, S1
Msemo, OA1
Theander, TG1
Alifrangis, M2
Schmiegelow, C1
Cates, JE1
Westreich, D1
Unger, HW2
Bauserman, M1
Adair, L1
Cole, SR1
Meshnick, S2
Rogerson, SJ2
Hallamaa, L1
Cheung, YB2
Luntamo, M2
Ashorn, U1
Kulmala, T2
Mangani, C1
Ashorn, P2
Maleta, K1
Mosha, D1
Chilongola, J1
Ndeserua, R1
Mwingira, F1
Genton, B1
Mbonye, AK1
Birungi, J1
Yanow, SK1
Shokoples, S1
Malamba, S1
Magnussen, P2
Cairns, M2
Bojang, K1
Coulibaly, SO2
Kayentao, K2
Abubakar, I1
Akor, F1
Mohammed, K1
Bationo, R1
Dabira, E1
Soulama, A1
Djimdé, M1
Guirou, E1
Awine, T1
Quaye, S1
Njie, F1
Ordi, J1
Doumbo, O2
Hodgson, A1
Oduro, A1
Taylor, S1
ter Kuile, F2
Woukeu, A1
Milligan, P1
Chandramohan, D1
Greenwood, B1
Wangnapi, RA1
Ome-Kaius, M1
Boeuf, P1
Karl, S1
Mueller, I1
Bouyou-Akotet, MK1
Mawili-Mboumba, DP1
Kendjo, E1
Moutandou Chiesa, S1
Tshibola Mbuyi, ML1
Tsoumbou-Bakana, G1
Zong, J1
Ambounda, N1
Kombila, M1
Walker, PG1
Floyd, J1
Gies, S2
Ouattara, FT1
D'Alessandro, U3
Msyamboza, KP1
Savage, EJ1
Kazembe, PN1
Kalanda, G1
Brabin, BJ2
van Eijk, AM2
Hand, CC1
Mwandagalirwa, K1
Messina, JP1
Tshefu, AK1
Atua, B1
Emch, M1
Muwonga, J1
Likwela, JL1
Lokwa, BL1
Meuris, S1
Dramaix, MW1
Huynh, BT1
Fievet, N1
Briand, V1
Borgella, S1
Massougbodji, A1
MORLEY, D1
WOODLAND, M1
CUTHBERTSON, WF1
Ayisi, JG1
Otieno, JA1
Misore, AO1
Odondi, JO1
Rosen, DH1
Kager, PA1
Steketee, RW1
Nahlen, BL1
Challis, K1
Osman, NB1
Cotiro, M1
Nordahl, G1
Dgedge, M1
Bergström, S1
Kodio, M1
Newman, RD1
Maiga, H1
Doumtabe, D1
Ongoiba, A1
Coulibaly, D1
Keita, AS1
Maiga, B1
Mungai, M1
Parise, ME1
Tukur, IU1
Thacher, TD1
Sagay, AS1
Madaki, JK1
Falade, CO1
Yusuf, BO1
Fadero, FF1
Mokuolu, OA1
Hamer, DH3
Salako, LA1
Hommerich, L1
von Oertzen, C1
Bedu-Addo, G1
Holmberg, V1
Acquah, PA1
Eggelte, TA1
Bienzle, U1
Mockenhaupt, FP1
Gill, CJ2
Macleod, WB2
Mwanakasale, V2
Chalwe, V2
Mwananyanda, L2
Champo, D2
Mukwamataba, D2
Chilengi, R2
Thea, DM2
Mubikayi, L1
Mulele, CK1
Mulenga, M1
Verhoeff, FH1
Chimsuku, L1
Kazembe, P1
Russell, WB1
Broadhead, RL1
Harrison, KA1
Ibeziako, PA1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Single-course Malaria Chemoprevention on Clearance of and Protection From Plasmodium Falciparum Infection in the Presence of Resistance-associated Genotypes in Cameroon[NCT06173206]Phase 3900 participants (Anticipated)Interventional2024-03-15Not yet recruiting
Prevention of Malaria in HIV-uninfected Pregnant Women and Infants[NCT02793622]Phase 3782 participants (Actual)Interventional2016-09-30Completed
Lungwena Antenatal Intervention Study. A Single-centre Intervention Trial in Rural Malawi, Testing Maternal and Infant Health Effects of Presumptive Intermittent Treatment of Pregnant Women With Sulfadoxine-pyrimethamine and Azithromycin[NCT00131235]Phase 31,320 participants (Actual)Interventional2003-12-31Active, not recruiting
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity[NCT05757167]Phase 42,500 participants (Anticipated)Interventional2023-11-06Recruiting
A Trial of Intermittent Preventive Treatment With Sulfadoxine-pyrimethamine Versus Intermittent Screening and Treatment of Malaria in Pregnancy[NCT01084213]Phase 45,354 participants (Actual)Interventional2010-06-30Completed
Assessing the Effectiveness of Community Delivery of Intermittent Preventive Treatment in Pregnancy (IPTp) in Malawi[NCT03376217]1,447 participants (Actual)Interventional2017-12-01Completed
Intermittent Preventive Treatment of Malaria With Sulfadoxine-Pyrimethamine in HIV-Seropositive and HIV-Seronegative Pregnant Women in Zambia[NCT00270530]Phase 4454 participants Interventional2002-11-30Completed
Intermittent Preventive Treatment With Azithromycin-containing Regimens for the Prevention of Malarial Infections and Anaemia and the Control of Sexually Transmitted Infections in Pregnant Women in Papua New Guinea[NCT01136850]Phase 32,793 participants (Actual)Interventional2009-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Complicated Malaria in Infants

Complicated malaria defined as an episode of malaria with danger signs (any of the following: less than 3 convulsions over 24 h, inability to sit or stand, vomiting everything, unable to breastfeed or drink) or the meeting standardized criteria for severe malaria. (NCT02793622)
Timeframe: Birth up to 12 months of age or early termination

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy44
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy24

Incidence of Hospital Admissions in Infants

Admission to the pediatric ward for any cause (NCT02793622)
Timeframe: Birth up to 12 months of age or early termination

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy19
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy8

Incidence of Malaria in Infants

episodes per person year (NCT02793622)
Timeframe: Time at risk will begin at birth and end when study participants reaches 12 months of age or early study termination

Interventionepisodes per person year (Number)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy1.98
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy1.71

Infant Mortality Rate

Any deaths occurring after birth (NCT02793622)
Timeframe: Birth up to 12 months of age

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy9
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy7

Mean Gestational Age in Weeks at Birth

Gestational age in weeks determined by ultrasound dating (gold standard) and by the metabolic profiling outcome from biological specimens including placental tissue and placental blood. (NCT02793622)
Timeframe: At the time of delivery

Interventionweeks (Mean)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy39.4
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy39.6

Number of Participants Who Deliver With a Composite Adverse Birth Outcome

Composite adverse birth outcome defined as any one of the following: 1) Low birth weight (< 2500 gm); 2) Preterm delivery (< 37 weeks gestational age); 3) Small for gestational age (< 10th percentile relative to an external growth reference) (NCT02793622)
Timeframe: Delivery

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy60
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy54

Number of Participants With Adverse Events

All grade 3 and 4 adverse events (NCT02793622)
Timeframe: Starting at the time of their first study drug administration, approximately gestational age between 12-20 weeks, up to one month post-delivery

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy54
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy43

Prevalence of Anemia in Infants

"Defined as the proportion with hemoglobin < 10 g/dL measure routinely at 12, 28, and 52 weeks of age. Number of cases per person year (PPY).~This is a prevalence measure but are repeated measures during infancy. In other words we measured this outcome up to 3 times for each participant during infancy (at 12, 28 and 52 weeks of age)." (NCT02793622)
Timeframe: Birth up to 12 months of age or early termination

Interventionroutine hemoglobin measurement (Count of Units)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy222
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy216

Prevalence of Anemia in Pregnant Women

hemoglobin < 11 g/dL (NCT02793622)
Timeframe: Starting at the time of their first study drug administration, approximately gestational age between 12-20 weeks, up to one month post-delivery

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy28
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy8

Prevalence of Asymptomatic Parasitemia in Infants

Proportion of routine monthly samples positive for parasites by microscopy and LAMP (NCT02793622)
Timeframe: Birth up to 12 months of age or early termination

Interventionblood smears (Count of Units)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy344
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy357

Prevalence of Asymptomatic Parasitemia in Pregnant Women

Proportion of routine monthly samples positive for parasites by microscopy and LAMP (NCT02793622)
Timeframe: Starting at the time of their first study drug administration, approximately gestational age between 12-20 weeks, up to one month post-delivery

Interventionblood smears (Count of Units)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy519
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy9

Prevalence of Maternal Malaria

Maternal blood positive for malaria parasites by microscopy. (NCT02793622)
Timeframe: Gestational age between 12-20 weeks (at study entry) up to delivery

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy28
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy1

Prevalence of Placental Malaria by Histology

Any evidence of placental infection (parasites or pigment). Number of participants with placental tissue positive for malaria parasites or pigment. (NCT02793622)
Timeframe: Delivery

InterventionParticipants (Count of Participants)
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy197
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy94

Prevalence of Placental Parasitemia

Proportion of placental blood samples positive for parasites by Loop-mediated isothermal amplification (LAMP) or microscopy (NCT02793622)
Timeframe: Delivery

,
InterventionParticipants (Count of Participants)
LAMPMicroscopy
Monthly Dihydroartemisinin-Piperaquine (DP) During Pregnancy71
Monthly Sulfadoxine-Pyrimethamine (SP) During Pregnancy7129

Reviews

2 reviews available for pyrimethamine and Birth Weight

ArticleYear
Malaria in pregnancy control and pregnancy outcomes: a decade's overview using Ghana's DHIMS II data.
    Malaria journal, 2022, Oct-27, Volume: 21, Issue:1

    Topics: Anemia; Antimalarials; Birth Weight; Drug Combinations; Female; Ghana; Humans; Malaria; Pregnancy; P

2022
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
    The Cochrane database of systematic reviews, 2022, 02-01, Volume: 2, Issue:2022

    Topics: Anemia; Antimalarials; Birth Weight; Child; Child, Preschool; Dietary Supplements; Female; Folic Aci

2022

Trials

17 trials available for pyrimethamine and Birth Weight

ArticleYear
Malaria chemoprophylaxis, infection of the placenta and birth weight in Gambian primigravidae.
    The Journal of tropical medicine and hygiene, 1994, Volume: 97, Issue:4

    Topics: Acute Disease; Antimalarials; Birth Weight; Chronic Disease; Dapsone; Double-Blind Method; Drug Comb

1994
The positive effect of malaria IPTp-SP on birthweight is mediated by gestational weight gain but modifiable by maternal carriage of enteric pathogens.
    EBioMedicine, 2022, Volume: 77

    Topics: Antimalarials; Birth Weight; Cryptosporidiosis; Cryptosporidium; Drug Combinations; Escherichia coli

2022
Effectiveness of Intermittent Screening and Treatment of Malaria in Pregnancy on Maternal and Birth Outcomes in Selected Districts in Rwanda: A Cluster Randomized Controlled Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 07-05, Volume: 77, Issue:1

    Topics: Anemia; Antimalarials; Birth Weight; Drug Combinations; Female; Humans; Infant, Newborn; Malaria; Pl

2023
Effects of maternal antenatal treatment with two doses of azithromycin added to monthly sulfadoxine-pyrimethamine for the prevention of low birth weight in Burkina Faso: an open-label randomized controlled trial.
    Malaria journal, 2023, Mar-17, Volume: 22, Issue:1

    Topics: Abortion, Spontaneous; Antimalarials; Azithromycin; Birth Weight; Burkina Faso; Drug Combinations; F

2023
Interactions Between Antenatal Sulfadoxine-Pyrimethamine, Drug-Resistant Plasmodium falciparum Parasites, and Delivery Outcomes in Malawi.
    The Journal of infectious diseases, 2020, 07-23, Volume: 222, Issue:4

    Topics: Adolescent; Adult; Animals; Birth Weight; Drug Combinations; Drug Resistance; Female; Genotype; Huma

2020
Overall, anti-malarial, and non-malarial effect of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine on birthweight: a mediation analysis.
    The Lancet. Global health, 2020, Volume: 8, Issue:7

    Topics: Adult; Antimalarials; Birth Weight; Drug Combinations; Female; Humans; Infant, Newborn; Kenya; Malar

2020
The impact of maternal antenatal treatment with two doses of azithromycin and monthly sulphadoxine-pyrimethamine on child weight, mid-upper arm circumference and head circumference: A randomized controlled trial.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Antimalarials; Arm; Azithromycin; Birth Weight; Child; Child, Preschoo

2019
The effect of antenatal monthly sulphadoxine-pyrimethamine, alone or with azithromycin, on foetal and neonatal growth faltering in Malawi: a randomised controlled trial.
    Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Antimalarials; Azithromycin; Birth Weight; Drug Administra

2013
A Non-Inferiority, Individually Randomized Trial of Intermittent Screening and Treatment versus Intermittent Preventive Treatment in the Control of Malaria in Pregnancy.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adolescent; Adult; Africa; Antimalarials; Birth Weight; Burkina Faso; Drug Combinations; Female; Gam

2015
A Non-Inferiority, Individually Randomized Trial of Intermittent Screening and Treatment versus Intermittent Preventive Treatment in the Control of Malaria in Pregnancy.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adolescent; Adult; Africa; Antimalarials; Birth Weight; Burkina Faso; Drug Combinations; Female; Gam

2015
A Non-Inferiority, Individually Randomized Trial of Intermittent Screening and Treatment versus Intermittent Preventive Treatment in the Control of Malaria in Pregnancy.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adolescent; Adult; Africa; Antimalarials; Birth Weight; Burkina Faso; Drug Combinations; Female; Gam

2015
A Non-Inferiority, Individually Randomized Trial of Intermittent Screening and Treatment versus Intermittent Preventive Treatment in the Control of Malaria in Pregnancy.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Adolescent; Adult; Africa; Antimalarials; Birth Weight; Burkina Faso; Drug Combinations; Female; Gam

2015
Individual efficacy of intermittent preventive treatment with sulfadoxine-pyrimethamine in primi- and secundigravidae in rural Burkina Faso: impact on parasitaemia, anaemia and birth weight.
    Tropical medicine & international health : TM & IH, 2009, Volume: 14, Issue:2

    Topics: Adult; Anemia; Animals; Antimalarials; Birth Weight; Burkina Faso; Drug Combinations; Female; Humans

2009
Consequences of gestational malaria on birth weight: finding the best timeframe for intermittent preventive treatment administration.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Antimalarials; Birth Weight; Drug Combinations; Female; Humans; Infant, Newborn;

2012
Impact of a double dose of sulphadoxine-pyrimethamine to reduce prevalence of pregnancy malaria in southern Mozambique.
    Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:10

    Topics: Adolescent; Adult; Antimalarials; Birth Weight; Double-Blind Method; Drug Administration Schedule; D

2004
Comparison of intermittent preventive treatment with chemoprophylaxis for the prevention of malaria during pregnancy in Mali.
    The Journal of infectious diseases, 2005, Jan-01, Volume: 191, Issue:1

    Topics: Abortion, Spontaneous; Adolescent; Adult; Anemia; Birth Weight; Chemoprevention; Chloroquine; Drug A

2005
A comparison of sulfadoxine-pyrimethamine with chloroquine and pyrimethamine for prevention of malaria in pregnant Nigerian women.
    The American journal of tropical medicine and hygiene, 2007, Volume: 76, Issue:6

    Topics: Adult; Animals; Antimalarials; Birth Weight; Chloroquine; Drug Combinations; Female; Hematocrit; Hum

2007
Intermittent preventive treatment with sulphadoxine-pyrimethamine is effective in preventing maternal and placental malaria in Ibadan, south-western Nigeria.
    Malaria journal, 2007, Jul-06, Volume: 6

    Topics: Adolescent; Adult; Antimalarials; Birth Weight; Dizziness; Drug Combinations; Female; Humans; Malari

2007
Inferiority of single-dose sulfadoxine-pyrimethamine intermittent preventive therapy for malaria during pregnancy among HIV-positive Zambian women.
    The Journal of infectious diseases, 2007, Dec-01, Volume: 196, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Anemia; Antimalarials; Birth Weight; Double-Blind Meth

2007
Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-seropositive pregnant Zambian women.
    The Journal of infectious diseases, 2007, Dec-01, Volume: 196, Issue:11

    Topics: Adult; AIDS-Related Opportunistic Infections; Anemia; Antimalarials; Birth Weight; Double-Blind Meth

2007

Other Studies

23 other studies available for pyrimethamine and Birth Weight

ArticleYear
Predicting the effect of sulfadoxine-pyrimethamine uptake by pregnant women on birth weight using a generalized ordered partial proportional odds model.
    BMC pregnancy and childbirth, 2022, Mar-19, Volume: 22, Issue:1

    Topics: Adult; Antimalarials; Birth Weight; Demography; Drug Combinations; Female; Fetal Macrosomia; Ghana;

2022
Intermittent preventive treatment with Sulphadoxine-Pyrimethamine (IPTp-SP) is associated with protection against sub-microscopic P. falciparum infection in pregnant women during the low transmission dry season in southwestern Cameroon: A Semi - longitudi
    PloS one, 2022, Volume: 17, Issue:9

    Topics: Antimalarials; Birth Weight; Cameroon; Drug Combinations; Female; Humans; Infant, Newborn; Insectici

2022
Peripheral and Placental Prevalence of Sulfadoxine-Pyrimethamine Resistance Markers in Plasmodium falciparum among Pregnant Women in Southern Province, Rwanda.
    The American journal of tropical medicine and hygiene, 2023, 11-01, Volume: 109, Issue:5

    Topics: Antimalarials; Birth Weight; Drug Combinations; Drug Resistance; Female; Humans; Malaria; Malaria, F

2023
The efficacy of intermittent preventive therapy in the eradication of peripheral and placental parasitemia in a malaria-endemic environment, as seen in a tertiary hospital in Abuja, Nigeria.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2020, Volume: 148, Issue:3

    Topics: Adolescent; Adult; Antimalarials; Birth Weight; Cross-Sectional Studies; Drug Combinations; Female;

2020
High uptake of Intermittent Preventive Treatment of malaria in pregnancy is associated with improved birth weight among pregnant women in Ghana.
    Scientific reports, 2019, 12-13, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Birth Weight; Cohort Studies; Drug Combinations; Female; Ghana; Humans; Linear Mo

2019
[Sulfadoxine-pyrimethamine-based intermittent preventive treatment in pregnant women and its effect on birth weight: application of 3-dosing regimen in the urban area of South Benin in 2017].
    The Pan African medical journal, 2019, Volume: 34

    Topics: Adult; Antimalarials; Benin; Birth Weight; Cross-Sectional Studies; Drug Combinations; Female; Human

2019
Defining the combined benefit of intermittent preventive malaria treatment in pregnancy.
    The Lancet. Global health, 2020, Volume: 8, Issue:7

    Topics: Antimalarials; Birth Weight; Drug Combinations; Female; Humans; Malaria; Pregnancy; Pyrimethamine; S

2020
Reduced Birth Weight Caused by Sextuple Drug-Resistant Plasmodium falciparum Infection in Early Second Trimester.
    The Journal of infectious diseases, 2021, 11-16, Volume: 224, Issue:9

    Topics: Adult; Antimalarials; Birth Weight; Drug Combinations; Drug Resistance; Female; Humans; Infant, Newb

2021
Intermittent Preventive Therapy in Pregnancy and Incidence of Low Birth Weight in Malaria-Endemic Countries.
    American journal of public health, 2018, Volume: 108, Issue:3

    Topics: Africa; Antimalarials; Birth Weight; Female; Humans; Malaria; Malnutrition; Pregnancy; Pyrimethamine

2018
Bigger babies for women given extra prophylaxis against malaria.
    BMJ (Clinical research ed.), 2013, Feb-13, Volume: 346

    Topics: Africa South of the Sahara; Antimalarials; Birth Weight; Drug Combinations; Female; Humans; Infant,

2013
Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on placental malaria, maternal anaemia and birthweight in areas with high and low malaria transmission intensity in Tanzania.
    Tropical medicine & international health : TM & IH, 2014, Volume: 19, Issue:9

    Topics: Adult; Anemia; Antimalarials; Birth Weight; Drug Combinations; Female; Humans; Infant, Low Birth Wei

2014
Prevalence of Plasmodium falciparum resistance markers to sulfadoxine-pyrimethamine among pregnant women receiving intermittent preventive treatment for malaria in Uganda.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:9

    Topics: Antimalarials; Bacterial Proteins; Birth Weight; Drug Combinations; Female; Humans; Malaria, Falcipa

2015
Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis.
    Maternal & child nutrition, 2016, Volume: 12, Issue:4

    Topics: Adolescent; Antimalarials; Azithromycin; Birth Weight; Body Mass Index; Drug Combinations; Female; F

2016
Decrease of microscopic Plasmodium falciparum infection prevalence during pregnancy following IPTp-SP implementation in urban cities of Gabon.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2016, Volume: 110, Issue:6

    Topics: Adult; Anemia; Antimalarials; Birth Weight; Cities; Cross-Sectional Studies; Drug Combinations; Fema

2016
Estimated impact on birth weight of scaling up intermittent preventive treatment of malaria in pregnancy given sulphadoxine-pyrimethamine resistance in Africa: A mathematical model.
    PLoS medicine, 2017, Volume: 14, Issue:2

    Topics: Africa South of the Sahara; Antimalarials; Birth Weight; Child; Child, Preschool; Drug Combinations;

2017
Community-based distribution of sulfadoxine-pyrimethamine for intermittent preventive treatment of malaria during pregnancy improved coverage but reduced antenatal attendance in southern Malawi.
    Tropical medicine & international health : TM & IH, 2009, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Anemia; Antimalarials; Birth Weight; Community Health Services; Drug Combinations

2009
Quantification of the burden and consequences of pregnancy-associated malaria in the Democratic Republic of the Congo.
    The Journal of infectious diseases, 2011, Dec-01, Volume: 204, Issue:11

    Topics: Anemia; Antimalarials; Birth Weight; Cross-Sectional Studies; Democratic Republic of the Congo; Drug

2011
Sulfadoxine-pyrimethamine resistance and intermittent preventive treatment during pregnancy: a retrospective analysis of birth weight data in the Democratic Republic of Congo (DRC).
    Tropical medicine & international health : TM & IH, 2012, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Antimalarials; Birth Weight; Congo; Drug Combinations; Drug Resistance; Female; F

2012
CONTROLLED TRIAL OF PYRIMETHAMINE IN PREGNANT WOMEN IN AN AFRICAN VILLAGE.
    British medical journal, 1964, Mar-14, Volume: 1, Issue:5384

    Topics: Birth Weight; Chloroquine; Female; Humans; Infant; Infant Mortality; Lactose; Malaria; Nigeria; Preg

1964
Effectiveness of intermittent preventive treatment with sulphadoxine-pyrimethamine for control of malaria in pregnancy in western Kenya: a hospital-based study.
    Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Antimalarials; Birth Weight; Cohort Studies; Drug Admi

2004
Decline of placental malaria in southern Ghana after the implementation of intermittent preventive treatment in pregnancy.
    Malaria journal, 2007, Nov-08, Volume: 6

    Topics: Adolescent; Adult; Anemia; Animals; Antimalarials; Birth Weight; Chemoprevention; Drug Administratio

2007
An evaluation of the effects of intermittent sulfadoxine-pyrimethamine treatment in pregnancy on parasite clearance and risk of low birthweight in rural Malawi.
    Annals of tropical medicine and parasitology, 1998, Volume: 92, Issue:2

    Topics: Adolescent; Adult; Antimalarials; Birth Weight; Drug Therapy, Combination; Female; Humans; Infant, L

1998
Maternal anaemia and fetal birthweight.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1973, Volume: 80, Issue:9

    Topics: Anemia; Anemia, Sickle Cell; Birth Weight; Blood Transfusion; Body Height; Chloroquine; Embryonic an

1973