pyrimethamine has been researched along with Autoimmune Diseases in 4 studies
Maloprim: contains above 2 cpds
Autoimmune Diseases: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pierdominici, M | 1 |
| Giammarioli, AM | 1 |
| Gambardella, L | 1 |
| De Felice, M | 1 |
| Quinti, I | 1 |
| Iacobini, M | 1 |
| Carbonari, M | 1 |
| Malorni, W | 1 |
| Giovannetti, A | 1 |
| Rao, VK | 1 |
| Dowdell, KC | 1 |
| Dale, JK | 1 |
| Dugan, F | 1 |
| Pesnicak, L | 1 |
| Bi, LL | 1 |
| Hoffmann, V | 1 |
| Penzak, S | 1 |
| Avila, NA | 1 |
| Fleisher, TA | 1 |
| Puck, JM | 1 |
| Straus, SE | 1 |
| van der Werff ten Bosch, JE | 1 |
| Demanet, C | 2 |
| Balduck, N | 1 |
| Bakkus, MH | 1 |
| De Raeve, H | 1 |
| Desprechins, B | 1 |
| Otten, J | 2 |
| Thielemans, K | 2 |
| van der Werff Ten Bosch, J | 1 |
| Schotte, P | 1 |
| Ferster, A | 1 |
| Azzi, N | 1 |
| Boehler, T | 1 |
| Laurey, G | 1 |
| Arola, M | 1 |
| Beyaert, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study of Pyrimethamine and Sulfadoxine (Fansidar) for the Treatment of Individuals With the Autoimmune Lymphoproliferative Syndrome (ALPS)[NCT00013689] | Phase 1 | 8 participants | Interventional | 2001-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for pyrimethamine and Autoimmune Diseases
| Article | Year |
|---|---|
Pyrimethamine (2,4-diamino-5-p-chlorophenyl-6-ethylpyrimidine) induces apoptosis of freshly isolated human T lymphocytes, bypassing CD95/Fas molecule but involving its intrinsic pathway.
Topics: Annexin A5; Apoptosis; Autoimmune Diseases; Caspase 10; Caspase 8; Caspases; Cells, Cultured; Child; | 2005 |
Pyrimethamine treatment does not ameliorate lymphoproliferation or autoimmune disease in MRL/lpr-/- mice or in patients with autoimmune lymphoproliferative syndrome.
Topics: Animals; Apoptosis; Autoimmune Diseases; Cell Death; Child; Humans; Infant; Infant, Newborn; Lymph N | 2007 |
The use of the anti-malaria drug Fansidar (pyrimethamine and sulphadoxine) in the treatment of a patient with autoimmune lymphoproliferative syndrome and Fas deficiency.
Topics: Antimalarials; Autoimmune Diseases; Drug Combinations; fas Receptor; Humans; Infant; Lymphoprolifera | 1998 |
Reversion of autoimmune lymphoproliferative syndrome with an antimalarial drug: preliminary results of a clinical cohort study and molecular observations.
Topics: Adolescent; Antimalarials; Apoptosis; Autoimmune Diseases; Case-Control Studies; Caspase 3; Caspases | 2002 |