pyrimethamine has been researched along with Anemia, Sickle Cell in 8 studies
Maloprim: contains above 2 cpds
Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of monthly SP presumptive treatment, versus weekly chloroquine for malaria prophylaxis in children attending the Sickle Cell Clinic, Mulago Hospital." | 9.14 | Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial. ( Nakiboneka, D; Nakibuuka, V; Ndeezi, G; Ndugwa, CM; Tumwine, JK, 2009) |
| "Children with sickle cell anemia (SCA) in areas of Africa with endemic malaria transmission are commonly prescribed malaria chemoprevention." | 7.11 | Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial. ( Clapp, S; Freedman, B; Green, CL; Kirui, JK; Korwa, S; Njuguna, FM; O'Meara, WP; Taylor, SM; Wu, A, 2022) |
| "To compare the efficacy of monthly SP presumptive treatment, versus weekly chloroquine for malaria prophylaxis in children attending the Sickle Cell Clinic, Mulago Hospital." | 5.14 | Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial. ( Nakiboneka, D; Nakibuuka, V; Ndeezi, G; Ndugwa, CM; Tumwine, JK, 2009) |
| "Children with sickle cell anemia (SCA) in areas of Africa with endemic malaria transmission are commonly prescribed malaria chemoprevention." | 3.11 | Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial. ( Clapp, S; Freedman, B; Green, CL; Kirui, JK; Korwa, S; Njuguna, FM; O'Meara, WP; Taylor, SM; Wu, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Enato, IG | 1 |
| Sadoh, AE | 1 |
| Ibadin, OM | 1 |
| Odunvbun, ME | 1 |
| Taylor, SM | 1 |
| Korwa, S | 1 |
| Wu, A | 1 |
| Green, CL | 1 |
| Freedman, B | 1 |
| Clapp, S | 1 |
| Kirui, JK | 1 |
| O'Meara, WP | 1 |
| Njuguna, FM | 1 |
| Nakibuuka, V | 1 |
| Ndeezi, G | 1 |
| Nakiboneka, D | 1 |
| Ndugwa, CM | 1 |
| Tumwine, JK | 1 |
| Diop, S | 1 |
| Soudré, F | 1 |
| Seck, M | 1 |
| Guèye, YB | 1 |
| Diéye, TN | 1 |
| Fall, AO | 1 |
| Sall, A | 1 |
| Thiam, D | 1 |
| Diakhaté, L | 1 |
| Okuonghae, HO | 1 |
| Nwankwo, MU | 1 |
| Offor, E | 1 |
| Davis, RE | 1 |
| Gilles, HM | 1 |
| Reid, HA | 1 |
| Odutola, A | 1 |
| Ransome-Kuti, O | 1 |
| Ransome-Kuti, S | 1 |
| Lesi, F | 1 |
| Harrison, KA | 1 |
| Ibeziako, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)[NCT03178643] | Phase 4 | 246 participants (Actual) | Interventional | 2018-01-23 | Completed | ||
| Efficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria: a Randomized Clinical Trial[NCT00124267] | Phase 3 | 108 participants | Interventional | 2003-09-30 | Active, not recruiting | ||
| Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Children With Sickle Cell Anaemia in Eastern and Southern Africa: a Double Blind Randomised Trial (CHEMCHA)[NCT04844099] | Phase 3 | 723 participants (Actual) | Interventional | 2021-04-09 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pyrimethamine and Anemia, Sickle Cell
| Article | Year |
|---|---|
Clinical chemistry of folic acid.
Topics: Absorption; Aged; Alcoholism; Anemia, Sickle Cell; Anticonvulsants; Arthritis, Rheumatoid; Biologica | 1986 |
3 trials available for pyrimethamine and Anemia, Sickle Cell
4 other studies available for pyrimethamine and Anemia, Sickle Cell
| Article | Year |
|---|---|
Prevalence of Molecular Markers of Plasmodium Falciparum Resistance to Proguanil and Pyrimethamine in Children with Haemoglobin Phenotypes SS and AA in Benin City, Nigeria.
Topics: Anemia, Sickle Cell; Antimalarials; Drug Combinations; Hemoglobin, Sickle; Humans; Malaria, Falcipar | 2021 |
Malarial parasitaemia in febrile children with sickle cell anaemia.
Topics: Adolescent; Anemia, Sickle Cell; Bacteremia; Child; Child, Preschool; Female; Fever; Gram-Negative B | 1992 |
Arvin treatment for sickle-cell crisis.
Topics: Adolescent; Anemia, Sickle Cell; Anticoagulants; Blood Coagulation Tests; Child; Child, Preschool; F | 1968 |
Maternal anaemia and fetal birthweight.
Topics: Anemia; Anemia, Sickle Cell; Birth Weight; Blood Transfusion; Body Height; Chloroquine; Embryonic an | 1973 |