pyrimethamine has been researched along with Alzheimer Disease in 1 studies
Maloprim: contains above 2 cpds
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tropak, MB | 1 |
| Zhang, J | 1 |
| Yonekawa, S | 1 |
| Rigat, BA | 1 |
| Aulakh, VS | 1 |
| Smith, MR | 1 |
| Hwang, HJ | 1 |
| Ciufolini, MA | 1 |
| Mahuran, DJ | 1 |
1 other study available for pyrimethamine and Alzheimer Disease
| Article | Year |
|---|---|
Pyrimethamine Derivatives: Insight into Binding Mechanism and Improved Enhancement of Mutant β-N-acetylhexosaminidase Activity.
Topics: Alzheimer Disease; beta-N-Acetylhexosaminidases; Cells, Cultured; Fibroblasts; Humans; Models, Molec | 2015 |