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pyrimethamine and Allergy, Drug

pyrimethamine has been researched along with Allergy, Drug in 17 studies

Maloprim: contains above 2 cpds

Research Excerpts

ExcerptRelevanceReference
"A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines."7.73Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis. ( Boyer, K; Jalbrzikowski, J; Khan, AR; Latkany, P; McLeod, R; Noble, GA, 2006)
"We report 3 cases of dapsone hypersensitivity syndrome due to anti-malarial chemoprophylactic treatment with maloprim, in military servicemen, presenting like a viral exanthem."7.72Dapsone hypersensitivity syndrome masquerading as a viral exanthem: three cases and a mini-review. ( Khoo, BP; Oh, HM; Poh, WT; Tee, AK; Wee, IY, 2004)
"To evaluate the safety and efficacy of a fixed 25mg pyrimethamine--500mg sulfadoxine combination plus 15mg folinic acid given twice weekly for the prevention of relapses of Pneumocystis carinii pneumonia (PCP) and primary episodes of toxoplasmic encephalitis."7.71Twice-weekly pyrimethamine-sulfadoxine effectively prevents Pneumocystis carinii pneumonia relapse and toxoplasmic encephalitis in patients with AIDS. ( Albrecht, H; Behnsch, M; Bergmann, F; Grobusch, M; Grünewald, T; Padberg, J; Ruf, B; Schürmann, D; Suttorp, N; Vallée, M; Wünsche, T, 2001)
"The efficacy and safety of 25 mg pyrimethamine plus 500 mg sulfadoxine given twice a week in preventing relapses of AIDS-related toxoplasmic encephalitis was evaluated in an open study."7.68Efficacy of pyrimethamine/sulfadoxine in the prevention of toxoplasmic encephalitis relapses and Pneumocystis carinii pneumonia in HIV-infected patients. ( Bergmann, F; Gottschalk, HJ; Grünewald, T; Pohle, HD; Ruf, B; Schüler-Maué, W; Schürmann, D; Witt, H, 1993)
"Hypersensitivity adverse drug reactions are much more common among patients with acquired immunodeficiency syndrome (AIDS) than in the general population."5.33Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro. ( Dekaban, GA; Rieder, MJ; Wijsman, JA, 2005)
"A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines."3.73Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis. ( Boyer, K; Jalbrzikowski, J; Khan, AR; Latkany, P; McLeod, R; Noble, GA, 2006)
"We report 3 cases of dapsone hypersensitivity syndrome due to anti-malarial chemoprophylactic treatment with maloprim, in military servicemen, presenting like a viral exanthem."3.72Dapsone hypersensitivity syndrome masquerading as a viral exanthem: three cases and a mini-review. ( Khoo, BP; Oh, HM; Poh, WT; Tee, AK; Wee, IY, 2004)
"To evaluate the safety and efficacy of a fixed 25mg pyrimethamine--500mg sulfadoxine combination plus 15mg folinic acid given twice weekly for the prevention of relapses of Pneumocystis carinii pneumonia (PCP) and primary episodes of toxoplasmic encephalitis."3.71Twice-weekly pyrimethamine-sulfadoxine effectively prevents Pneumocystis carinii pneumonia relapse and toxoplasmic encephalitis in patients with AIDS. ( Albrecht, H; Behnsch, M; Bergmann, F; Grobusch, M; Grünewald, T; Padberg, J; Ruf, B; Schürmann, D; Suttorp, N; Vallée, M; Wünsche, T, 2001)
"The efficacy and safety of 25 mg pyrimethamine plus 500 mg sulfadoxine given twice a week in preventing relapses of AIDS-related toxoplasmic encephalitis was evaluated in an open study."3.68Efficacy of pyrimethamine/sulfadoxine in the prevention of toxoplasmic encephalitis relapses and Pneumocystis carinii pneumonia in HIV-infected patients. ( Bergmann, F; Gottschalk, HJ; Grünewald, T; Pohle, HD; Ruf, B; Schüler-Maué, W; Schürmann, D; Witt, H, 1993)
"A patient developed eosinophilic peripheral pulmonary infiltrates while receiving malaria prophylaxis with sulfadoxine-pyrimethamine (Fansidar)."3.67Sulfadoxine specific lymphocyte transformation in a patient with eosinophilic pneumonia induced by sulfadoxine-pyrimethamine (Fansidar). ( Berg, PA; Daniel, PT; Holzschuh, J, 1989)
"As a result of this drug allergy, the patient did not receive prophylaxis with trimethoprim and sulfamethoxazole."1.37Acquired toxoplasmosis after orthotopic heart transplantation in a sulfonamide-allergic patient. ( Caldwell, R; Cox, E; Debrunner, M; Sanchez Mejia, A, 2011)
"Hypersensitivity adverse drug reactions are much more common among patients with acquired immunodeficiency syndrome (AIDS) than in the general population."1.33Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro. ( Dekaban, GA; Rieder, MJ; Wijsman, JA, 2005)
"A pregnant woman was diagnosed with central nervous system toxoplasmosis and human immunodeficiency virus infection."1.29Normal fetal outcome in a pregnancy with central nervous system toxoplasmosis and human immunodeficiency virus infection. A case report. ( Brown, GM; Hedriana, HL; Mitchell, JL; Williams, SB, 1993)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19906 (35.29)18.7374
1990's3 (17.65)18.2507
2000's6 (35.29)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tee, AK1
Oh, HM1
Wee, IY1
Khoo, BP1
Poh, WT1
Thong, BY1
Leong, KP1
Chng, HH1
Yusuf, IH1
Sahare, P1
Hildebrand, GD1
Sanchez Mejia, A1
Debrunner, M1
Cox, E1
Caldwell, R1
Adam, I1
Elbashir, MI1
Wijsman, JA1
Dekaban, GA1
Rieder, MJ1
McLeod, R1
Khan, AR1
Noble, GA1
Latkany, P1
Jalbrzikowski, J1
Boyer, K1
Dyban, AP1
Akimova, IM1
Hedriana, HL1
Mitchell, JL1
Brown, GM1
Williams, SB1
Ruf, B2
Schürmann, D2
Bergmann, F2
Schüler-Maué, W1
Grünewald, T2
Gottschalk, HJ1
Witt, H1
Pohle, HD1
Okazaki, Y1
Watanabe, N1
Uchiyama, J1
Nakano, A1
Nishizaki, Y1
Kagawa, T1
Matsuzaki, S1
Albrecht, H1
Padberg, J1
Behnsch, M1
Grobusch, M1
Vallée, M1
Wünsche, T1
Suttorp, N1
Costello, JM1
Becroft, DM1
Daniel, PT1
Holzschuh, J1
Berg, PA1
Gottlieb, MS1
Young, LS1
McCormack, D1
Morgan, WK1
Laing, AB1

Other Studies

17 other studies available for pyrimethamine and Allergy, Drug

ArticleYear
Dapsone hypersensitivity syndrome masquerading as a viral exanthem: three cases and a mini-review.
    Annals of the Academy of Medicine, Singapore, 2004, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Antimalarials; Dapsone; Diagnosis, Differential; Drug Combinations; Drug Eruption

2004
Hypersensitivity syndrome associated with dapsone/pyrimethamine (Maloprim) antimalaria chemoprophylaxis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:5

    Topics: Adult; Antimalarials; Dapsone; Drug Combinations; Drug Hypersensitivity; Glucocorticoids; Humans; Ma

2002
DRESS syndrome in a child treated for toxoplasma retinochoroiditis.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2013, Volume: 17, Issue:5

    Topics: Adolescent; Antiprotozoal Agents; Chorioretinitis; Drug Eruptions; Drug Hypersensitivity; Drug Thera

2013
Acquired toxoplasmosis after orthotopic heart transplantation in a sulfonamide-allergic patient.
    Pediatric cardiology, 2011, Volume: 32, Issue:1

    Topics: Adult; Antibiotic Prophylaxis; Antiparasitic Agents; Clindamycin; Drug Hypersensitivity; Folic Acid;

2011
Extrapyramidal syndrome after treatment of falciparum malaria with sulphadoxine-pyrimethamine.
    Saudi medical journal, 2004, Volume: 25, Issue:9

    Topics: Adult; Animals; Antimalarials; Basal Ganglia Diseases; Drug Hypersensitivity; Drug Therapy, Combinat

2004
Differential toxicity of reactive metabolites of clindamycin and sulfonamides in HIV-infected cells: influence of HIV infection on clindamycin toxicity in vitro.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:3

    Topics: Animals; Anti-Infective Agents; Biotransformation; Cell Line; Cell Survival; Clindamycin; Coculture

2005
Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis.
    The Pediatric infectious disease journal, 2006, Volume: 25, Issue:3

    Topics: Animals; Antiprotozoal Agents; Child; Chorioretinitis; Drug Hypersensitivity; Drug Therapy, Combinat

2006
[The significance of group B vitamins and genetic factors on the reaction of the rat embryo to thalidomide].
    Arkhiv anatomii, gistologii i embriologii, 1966, Volume: 51, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Diet; Drug Hypersensitivity; E

1966
Normal fetal outcome in a pregnancy with central nervous system toxoplasmosis and human immunodeficiency virus infection. A case report.
    The Journal of reproductive medicine, 1993, Volume: 38, Issue:9

    Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Antibodies, Protozoan; Drug Hypersensitivity;

1993
Efficacy of pyrimethamine/sulfadoxine in the prevention of toxoplasmic encephalitis relapses and Pneumocystis carinii pneumonia in HIV-infected patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:5

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drug Administration Schedule; D

1993
[A case of hypersensitivity type of liver injury induced by pyrimetamine and sulfadoxin (Fansidar)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1997, Volume: 94, Issue:2

    Topics: Adult; Antimalarials; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Hypersensitivi

1997
Twice-weekly pyrimethamine-sulfadoxine effectively prevents Pneumocystis carinii pneumonia relapse and toxoplasmic encephalitis in patients with AIDS.
    The Journal of infection, 2001, Volume: 42, Issue:1

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Cohort Studies; Drug Comb

2001
Drug reaction simulating malignant lymphoma: a case due to pyrimethamine.
    The New Zealand medical journal, 1977, Nov-09, Volume: 86, Issue:599

    Topics: Child; Diagnosis, Differential; Drug Hypersensitivity; Humans; Lymphoma; Male; Pyrimethamine

1977
Sulfadoxine specific lymphocyte transformation in a patient with eosinophilic pneumonia induced by sulfadoxine-pyrimethamine (Fansidar).
    Thorax, 1989, Volume: 44, Issue:4

    Topics: Adult; Antimalarials; Drug Combinations; Drug Hypersensitivity; Female; Humans; Lymphocyte Activatio

1989
Adverse reactions to pyrimethamine-sulfadoxine in context of AIDS.
    Lancet (London, England), 1985, Jun-15, Volume: 1, Issue:8442

    Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Drug Hypersensitivity; Humans; Pyrimethamine;

1985
Fansidar hypersensitivity pneumonitis.
    British journal of diseases of the chest, 1987, Volume: 81, Issue:2

    Topics: Alveolitis, Extrinsic Allergic; Antimalarials; Drug Combinations; Drug Hypersensitivity; Humans; Mal

1987
Antimalarial effects of sulphormethoxine, diaphenylsulphone and separate combinations of these with pyrimethamine: a review of preliminary investigations carried out in Tanzania.
    The Journal of tropical medicine and hygiene, 1968, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Antimalarials; Child; Chloroquine; Dapsone; Drug Hypersensitivity; Drug Resistanc

1968