pyrimethamine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ajroud-Driss, S; Andersen, PM; Appel, SH; Doretti, A; Fields, KG; Lange, DJ; Ludolph, AC; Maderna, L; Marklund, SL; Messina, S; Morelli, C; Remanan, R; Shahbazi, M; Silani, V; Weiland, U; Weishaupt, JH | 1 |
| Brown, RH; Glicksman, M; Huang, M; Matthews, J; Weiss, A; Wightman, N; Wright, PD | 1 |
| Andersen, PM; Benjamin, D; Lange, DJ; Marklund, S; Remanan, R | 1 |
| Costi, MP; Ferrari, S; Guerrieri, D; Michels, PA | 1 |
2 trial(s) available for pyrimethamine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Pyrimethamine significantly lowers cerebrospinal fluid Cu/Zn superoxide dismutase in amyotrophic lateral sclerosis patients with SOD1 mutations.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Female; Folic Acid Antagonists; Humans; Male; Middle Aged; Mutation; Pyrimethamine; Severity of Illness Index; Superoxide Dismutase-1; Treatment Outcome; Young Adult | 2017 |
Pyrimethamine decreases levels of SOD1 in leukocytes and cerebrospinal fluid of ALS patients: a phase I pilot study.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Female; Humans; Leukocytes; Male; Middle Aged; Pilot Projects; Pyrimethamine; Superoxide Dismutase; Superoxide Dismutase-1 | 2013 |
2 other study(ies) available for pyrimethamine and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Screening for inhibitors of the SOD1 gene promoter: pyrimethamine does not reduce SOD1 levels in cell and animal models.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Drug Evaluation, Preclinical; Folic Acid Antagonists; Gene Expression; HeLa Cells; Humans; Mice; Mice, Inbred C57BL; PC12 Cells; Promoter Regions, Genetic; Pyrimethamine; Rats; Superoxide Dismutase; Superoxide Dismutase-1 | 2010 |
Biochemical effects of riluzole on Leishmania parasites.
Topics: Amyotrophic Lateral Sclerosis; Anticonvulsants; Antiprotozoal Agents; Cell Line; Enzyme Inhibitors; Humans; Leishmania major; Leishmania mexicana; Neuroprotective Agents; Oxidative Stress; Oxidoreductases; Pyrimethamine; Riluzole | 2013 |