pyrilamine has been researched along with Rhinitis, Allergic, Perennial in 8 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The histamine-induced increase in intranasal pressure was significantly augmented after repeated antigen challenge, indicating that nasal hyperresponsiveness was achieved." | 1.31 | Elevated nasal mucosal G protein levels and histamine receptor affinity in a guinea pig model of nasal hyperresponsiveness. ( Chiba, Y; Matsuo, K; Misawa, M; Saitoh, N, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menciu, C | 1 |
| Duflos, M | 1 |
| Fouchard, F | 1 |
| Le Baut, G | 1 |
| Emig, P | 1 |
| Achterrath, U | 1 |
| Szelenyi, I | 1 |
| Nickel, B | 1 |
| Schmidt, J | 1 |
| Kutscher, B | 1 |
| Günther, E | 1 |
| Slack, RJ | 1 |
| Russell, LJ | 1 |
| Hall, DA | 1 |
| Luttmann, MA | 1 |
| Ford, AJ | 1 |
| Saunders, KA | 1 |
| Hodgson, ST | 1 |
| Connor, HE | 1 |
| Browning, C | 1 |
| Clark, KL | 1 |
| Yang, TQ | 1 |
| Takeuchi, K | 1 |
| Hayashi, S | 1 |
| Majima, Y | 1 |
| Narita, S | 1 |
| Asakura, K | 1 |
| Fujita, M | 1 |
| Yonetomi, Y | 1 |
| Takeda, H | 1 |
| Nakagawa, N | 1 |
| Kawabata, K | 1 |
| Ohno, H | 1 |
| Mizutani, N | 1 |
| Nabe, T | 1 |
| Sasaki, K | 1 |
| Takenaka, H | 1 |
| Kohno, S | 1 |
| Liu, T | 1 |
| Yang, P | 1 |
| Wang, B | 1 |
| Chiba, Y | 1 |
| Saitoh, N | 1 |
| Matsuo, K | 1 |
| Misawa, M | 1 |
8 other studies available for pyrilamine and Rhinitis, Allergic, Perennial
| Article | Year |
|---|---|
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbac | 1999 |
Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptors.
Topics: Allergens; Animals; Benzazepines; Binding, Competitive; Bronchi; Bronchial Provocation Tests; Bronch | 2011 |
Effect of histamine on the permeability of the nasal mucosa in vivo.
Topics: Adult; Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Guinea Pigs; Histamine | 2003 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization | 1993 |
Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Chromones; Cyclooxygenase I | 1997 |
Nasal hyperresponsiveness to histamine induced by repetitive exposure to cedar pollen in guinea-pigs.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Atropine; Disease Models, Animal; | 1999 |
[Effect of substance P on the short-circuit current of nasal mucosal epithelium].
Topics: Animals; Biphenyl Compounds; Electrophysiology; Epithelium; Histamine H1 Antagonists; Histamine H2 A | 1998 |
Elevated nasal mucosal G protein levels and histamine receptor affinity in a guinea pig model of nasal hyperresponsiveness.
Topics: Animals; Area Under Curve; Binding, Competitive; Blotting, Western; Disease Models, Animal; GTP-Bind | 2002 |