Page last updated: 2024-11-03

pyrilamine and Pregnancy

pyrilamine has been researched along with Pregnancy in 19 studies

Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"We investigated the characteristic changes in histamine-induced, endothelium-derived nitric oxide (NO)-mediated relaxation in human omental resistance arteries seen in pre-eclampsia."7.70Modified histamine-induced NO-mediated relaxation in resistance arteries in pre-eclampsia. ( Itoh, T; Kajikuri, J; Suzuki, Y; Suzumori, K; Yamamoto, T, 2000)
"We investigated the characteristic changes in histamine-induced, endothelium-derived nitric oxide (NO)-mediated relaxation in human omental resistance arteries seen in pre-eclampsia."3.70Modified histamine-induced NO-mediated relaxation in resistance arteries in pre-eclampsia. ( Itoh, T; Kajikuri, J; Suzuki, Y; Suzumori, K; Yamamoto, T, 2000)
"Responses to histamine have been studied on ring preparations of epigastric artery obtained from normal and from pregnancy-induced hypertensive (PIH) women to characterize the mode of action of histamine in this vascular preparation."3.68Responses of isolated human epigastric arteries to histamine. ( Cabanie, M; Ebeigbe, AB, 1992)
"Cumulative dose-response curves for histamine induced responses in mesometrial (ME) and antimesometrial (AME) regions of uterine horns isolated from rats at 7th, 16th and 22nd days of pregnancy, were constructed."3.67Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation? ( Dveksler, G; Franchi, AM; Gimeno, AL; Gimeno, MF; Viggiano, M, 1987)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's6 (31.58)18.2507
2000's4 (21.05)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Szukiewicz, D1
Szewczyk, G1
Mittal, TK1
Rongies, W1
Maslinski, S1
Matsuyama, K2
Kawakami, N1
Ichikawa, T2
Nitta, Y2
Ishimura, K2
Horio, S2
Fukui, H2
Ikoma, Y1
Hoos, PC1
Hoffman, LH1
Baenziger, NL1
Force, LE1
Becherer, PR1
Mehrotra, PK1
Subramanian, N1
Whitmore, WL1
Slotkin, TA1
Izumi, H1
Garfield, RE1
Makino, Y1
Shirakawa, K1
Itoh, T2
Gonzalez, R1
Reinicke, K1
Rudolph, GM1
Anesini, C1
Genaro, A1
Cremaschi, G1
Zubillaga, M1
Boccio, J1
Sterin-Borda, L1
Borda, E1
Luckman, SM1
Larsen, PJ1
Sewram, V1
Raynor, MW1
Mulholland, DA1
Raidoo, DM1
Suzuki, Y1
Yamamoto, T1
Suzumori, K1
Kajikuri, J1
Ebeigbe, AB1
Cabanie, M1
Cruz, MA2
González, C2
Sepúlveda, WH2
Rudolph, MI2
Acevedo, CG1
Revtyak, GE1
Hughes, MJ1
Johnson, AR1
Campbell, WB1
Viggiano, M1
Franchi, AM1
Dveksler, G1
Gimeno, MF1
Gimeno, AL1
Serbus, DC1
Stull, RE1
Light, KE1

Other Studies

19 other studies available for pyrilamine and Pregnancy

ArticleYear
Involvement of histamine and histamine H2 receptors in nicotinamide-induced differentiation of human amniotic epithelial cells into insulin-producing cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59 Suppl 2

    Topics: Adult; Amniotic Fluid; C-Peptide; Cell Differentiation; Cells, Cultured; Cimetidine; Epithelial Cell

2010
Expression of histamine H(1) receptor in placenta.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53 Suppl 1

    Topics: Animals; CHO Cells; Competitive Bidding; Cricetinae; Cricetulus; Female; Humans; Placenta; Pregnancy

2004
Localized expression of histamine H1 receptors in syncytiotrophoblast cells of human placenta.
    Journal of pharmacological sciences, 2006, Volume: 102, Issue:3

    Topics: Adult; Animals; Blotting, Western; Chlorpheniramine; CHO Cells; Chorionic Gonadotropin; Chorionic Vi

2006
Effect of histamine receptor antagonists and indomethacin on implantation in the rabbit.
    Biology of reproduction, 1983, Volume: 29, Issue:4

    Topics: Aminopyridines; Animals; Capillary Permeability; Cimetidine; Drug Combinations; Drug Interactions; E

1983
Histamine stimulate prostacyclin synthesis in cultured human umbilical vein endothelial cells.
    Biochemical and biophysical research communications, 1980, Feb-27, Volume: 92, Issue:4

    Topics: Cimetidine; Dose-Response Relationship, Drug; Endothelium; Epoprostenol; Female; Histamine; Humans;

1980
Effect of some nonsteroidal substances on decidual cell reaction in immature rats.
    Indian journal of experimental biology, 1982, Volume: 20, Issue:9

    Topics: Animals; Centchroman; Clomiphene; Decidua; Female; Indomethacin; Pregnancy; Pyrilamine; Rats; Seroto

1982
Trans-synaptic modulation of histamine H-1 receptor development in rat brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1981, Volume: 1, Issue:6

    Topics: Animals; Animals, Newborn; Brain; Diphenhydramine; Female; Histamine; Hypothalamus; Pregnancy; Pyril

1981
Gestational changes in endothelium-dependent vasorelaxation in human umbilical artery.
    American journal of obstetrics and gynecology, 1994, Volume: 170, Issue:1 Pt 1

    Topics: Arginine; Biological Assay; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Histami

1994
Histamine H1 receptor binding sites in mouse uterine horns.
    General pharmacology, 1993, Volume: 24, Issue:1

    Topics: Animals; Cimetidine; Estrus; Female; Gonadal Steroid Hormones; Histamine; In Vitro Techniques; Kinet

1993
"In vivo" and "in vitro" antitumoral action of Larrea divaricata Cav.
    Acta physiologica, pharmacologica et therapeutica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y [de] la Asociacion Latinoamericana de Farmacologia, 1996, Volume: 46, Issue:1

    Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Division; Cimetidi

1996
Evidence for the involvement of histaminergic neurones in the regulation of the rat oxytocinergic system during pregnancy and parturition.
    The Journal of physiology, 1997, Jun-15, Volume: 501 ( Pt 3)

    Topics: Afferent Pathways; Animals; Cimetidine; Female; Histamine; Histamine Antagonists; Histidine Decarbox

1997
The uterotonic activity of compounds isolated from the supercritical fluid extract of Ekebergia capensis.
    Journal of pharmaceutical and biomedical analysis, 2000, Volume: 24, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Female; Guinea Pigs; In Vitro Techniques; Plant Extra

2000
Modified histamine-induced NO-mediated relaxation in resistance arteries in pre-eclampsia.
    European journal of pharmacology, 2000, Dec-20, Volume: 410, Issue:1

    Topics: Adult; Arteries; Atrial Natriuretic Factor; Cyclic GMP; Down-Regulation; Endothelium, Vascular; Famo

2000
Responses of isolated human epigastric arteries to histamine.
    Journal of the autonomic nervous system, 1992, Volume: 39, Issue:3

    Topics: Abdominal Muscles; Arteries; Diuretics; Endothelium; Female; Histamine; Histamine Antagonists; Human

1992
Effect of histamine on human placental chorionic veins: interaction with serotonin.
    Pharmacology, 1991, Volume: 42, Issue:2

    Topics: Chorion; Cimetidine; Drug Interactions; Female; Histamine; Humans; In Vitro Techniques; Muscle Contr

1991
Effects of histamine and serotonin on the contractility of isolated pregnant and nonpregnant human myometrium.
    Gynecologic and obstetric investigation, 1989, Volume: 28, Issue:1

    Topics: Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine; Humans; In Vitro

1989
Histamine stimulation of prostaglandin and HETE synthesis in human endothelial cells.
    The American journal of physiology, 1988, Volume: 255, Issue:2 Pt 1

    Topics: Arachidonic Acids; Carbon Radioisotopes; Cells, Cultured; Endothelium, Vascular; Female; Gas Chromat

1988
Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation?
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 28, Issue:3

    Topics: Alprostadil; Animals; Aspirin; Chlorpheniramine; Cimetidine; Dinoprost; Dinoprostone; Female; Histam

1987
Neonatal ethanol exposure to rat pups: resultant alterations of cortical muscarinic and cerebellar H1-histaminergic receptor binding dynamics.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Ethanol; Female; Fetal Alcohol S

1986