pyrilamine has been researched along with Nasal Obstruction in 2 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Nasal Obstruction: Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Montelukast has not been reported to have major effects on sneezing and itching in the clinic but reduces nasal obstruction (lower nasal airway pressure or nasal patency)." | 1.35 | Differential responses to various classes of drugs in a model of allergic rhinitis in guinea pigs. ( Al Suleimani, YM; Dong, Y; Walker, MJ, 2008) |
| "Biphasic nasal blockage and sneezing after the challenge in Group A-2 were more severe than those in Group A-0, while those of Group B-7 were almost the same as those of Group B-0." | 1.32 | Acquired nasal hyperresponsiveness aggravates antigen-induced rhinitis in the guinea pig. ( Kohno, S; Mizutani, N; Nabe, T; Takenaka, H, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizutani, N | 1 |
| Nabe, T | 1 |
| Takenaka, H | 1 |
| Kohno, S | 1 |
| Al Suleimani, YM | 1 |
| Dong, Y | 1 |
| Walker, MJ | 1 |
2 other studies available for pyrilamine and Nasal Obstruction
| Article | Year |
|---|---|
Acquired nasal hyperresponsiveness aggravates antigen-induced rhinitis in the guinea pig.
Topics: Animals; Antigens; Chromones; Disease Models, Animal; Guinea Pigs; Histamine H1 Antagonists; Leukotr | 2003 |
Differential responses to various classes of drugs in a model of allergic rhinitis in guinea pigs.
Topics: Acetates; Acute Disease; Animals; Cetirizine; Cyclopropanes; Dexamethasone; Disease Models, Animal; | 2008 |