pyrilamine has been researched along with Infarction, Middle Cerebral Artery in 3 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Focal cerebral ischemia for 2 h by occlusion of the right middle cerebral artery provoked severe brain infarction in the rat brain after 24 h." | 1.33 | Prevention of brain infarction by postischemic administration of histidine in rats. ( Adachi, N; Arai, T; Liu, K, 2005) |
| "Histidine was administered four times, immediately, 6, 24, and 48 h after reperfusion of blood flow (1000 mg/kg, i." | 1.32 | Alleviation of ischemic neuronal damage by postischemic loading with histidine in the rat striatum. ( Adachi, N; Arai, T; Liu, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, N | 3 |
| Liu, K | 3 |
| Arai, T | 3 |
| Hiraga, N | 1 |
| Nagaro, T | 1 |
3 other studies available for pyrilamine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Alleviation of ischemic neuronal damage by postischemic loading with histidine in the rat striatum.
Topics: Animals; Brain Ischemia; Cell Count; Corpus Striatum; Drug Interactions; Functional Laterality; Hist | 2004 |
Prevention of brain infarction by postischemic administration of histidine in rats.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Functional Laterality; Histamine H1 Antagonists; Hi | 2005 |
Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains.
Topics: Animals; Antigens, CD; Brain Ischemia; CD4-Positive T-Lymphocytes; Cell Count; Drug Combinations; Hi | 2007 |