pyrilamine has been researched along with Hyperemia in 7 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Hyperemia: The presence of an increased amount of blood in a body part or an organ leading to congestion or engorgement of blood vessels. Hyperemia can be due to increase of blood flow into the area (active or arterial), or due to obstruction of outflow of blood from the area (passive or venous).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Subsequent dose-response studies with other serotonergic and dopaminergic antagonists suggested that dopaminergic receptors are involved in the adaptive response to the irritant." | 1.28 | A role for dopamine as an endogenous protective factor in the rat stomach. ( MacNaughton, WK; Wallace, JL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pellinger, TK | 1 |
| Simmons, GH | 1 |
| Maclean, DA | 1 |
| Halliwill, JR | 1 |
| Wong, BJ | 1 |
| Williams, SJ | 1 |
| Minson, CT | 1 |
| Argenbright, LW | 1 |
| Forbes, PD | 1 |
| Stewart, GJ | 1 |
| Clark, KE | 1 |
| Farley, DB | 1 |
| Van Orden, DE | 1 |
| Brody, MJ | 1 |
| MacNaughton, WK | 1 |
| Wallace, JL | 1 |
| Woodward, DF | 1 |
| Johnson, L | 1 |
| Spada, C | 1 |
| Chen, J | 1 |
| Leon, J | 1 |
| Charap, A | 1 |
| Duzman, E | 1 |
| Shen, CD | 1 |
2 trials available for pyrilamine and Hyperemia
| Article | Year |
|---|---|
Local histamine H(1-) and H(2)-receptor blockade reduces postexercise skeletal muscle interstitial glucose concentrations in humans.
Topics: Adult; Cimetidine; Ethanol; Exercise; Extracellular Space; Female; Glucose; Histamine H1 Antagonists | 2010 |
Efficacy of cimetidine/pyrilamine eyedrops. A dose response study with histamine challenge.
Topics: Adult; Aminopyridines; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug | 1986 |
5 other studies available for pyrilamine and Hyperemia
| Article | Year |
|---|---|
Minimal role for H1 and H2 histamine receptors in cutaneous thermal hyperemia to local heating in humans.
Topics: Adult; Enzyme Inhibitors; Female; Forearm; Histamine H1 Antagonists; Hot Temperature; Humans; Hypere | 2006 |
Quantitation of phototoxic hyperemia and permeability to protein: II. Inhibition by histamine (H1 and H2) receptor antagonists in mouse skin.
Topics: Animals; Anthracenes; Blood Circulation; Capillary Permeability; Cimetidine; Female; Hyperemia; Male | 1980 |
Estrogen-induced uterine hyperemia and edema persist during histamine receptor blockade.
Topics: Animals; Burimamide; Capillary Permeability; Edema; Estradiol; Female; Hyperemia; Pyrilamine; Rats; | 1977 |
A role for dopamine as an endogenous protective factor in the rat stomach.
Topics: Animals; Cyproheptadine; Dopamine; Dopamine Agents; Dopamine Antagonists; Ethanol; Gastric Mucosa; H | 1989 |
Effect of cimetidine and pyrilamine on histamine-induced ocular surface hyperemia.
Topics: Aminopyridines; Animals; Cimetidine; Drug Therapy, Combination; Eye Diseases; Female; Histamine; Hyp | 1986 |