pyrilamine has been researched along with Glioma in 6 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Molecular events involved in the homologous desensitization of histamine-mediated signal transduction system in glioma cells are not well understood." | 7.79 | Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells. ( Tseng, CL; Wei, JW, 2013) |
| "Information related to histamine-induced cellular responses in C6 glioma cells through second messenger pathways has not been fully studied, especially the involvement of arachidonic acid (AA) metabolism." | 7.78 | Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms. ( Tseng, CL; Wei, JW, 2012) |
| " The effects of histamine receptor agonists and antagonists on phospholipid hydrolysis in rat-derived C6 glioma cells have been investigated." | 7.69 | Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP. ( Hill, SJ; Peakman, MC, 1994) |
| "Molecular events involved in the homologous desensitization of histamine-mediated signal transduction system in glioma cells are not well understood." | 3.79 | Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells. ( Tseng, CL; Wei, JW, 2013) |
| "Information related to histamine-induced cellular responses in C6 glioma cells through second messenger pathways has not been fully studied, especially the involvement of arachidonic acid (AA) metabolism." | 3.78 | Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms. ( Tseng, CL; Wei, JW, 2012) |
| " The effects of histamine receptor agonists and antagonists on phospholipid hydrolysis in rat-derived C6 glioma cells have been investigated." | 3.69 | Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP. ( Hill, SJ; Peakman, MC, 1994) |
| "The authors studied the effect of intracarotid administration of histamine on the regional cerebral blood flow (rCBF) in transplanted rat C6 glioma by the hydrogen clearance method." | 3.68 | Altered response to histamine in brain tumor vessels: the selective increase of regional cerebral blood flow in transplanted rat brain tumor. ( Fukui, M; Ikezaki, K; Natori, Y; Nomura, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tseng, CL | 2 |
| Wei, JW | 2 |
| Fujimoto, K | 2 |
| Horio, Y | 2 |
| Sugama, K | 1 |
| Ito, S | 1 |
| Liu, YQ | 2 |
| Fukui, H | 2 |
| Peakman, MC | 1 |
| Hill, SJ | 1 |
| Nomura, T | 1 |
| Ikezaki, K | 1 |
| Natori, Y | 1 |
| Fukui, M | 1 |
| Mizuguchi, H | 1 |
| Imamura, I | 1 |
| Abe, Y | 1 |
6 other studies available for pyrilamine and Glioma
| Article | Year |
|---|---|
Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells.
Topics: Animals; Arachidonic Acid; Brain Neoplasms; Calcium; Cell Line, Tumor; Glioma; Histamine; Inositol P | 2013 |
Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms.
Topics: Animals; Arachidonic Acid; Calcium; Cell Line, Tumor; Egtazic Acid; Glioma; Glycosylphosphatidylinos | 2012 |
Genomic cloning of the rat histamine H1 receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; DNA; Genomic Library; Gliom | 1993 |
Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP.
Topics: Animals; Cyclic AMP; Glioma; Histamine; Histamine Agonists; Histamine H1 Antagonists; Hydrolysis; Li | 1994 |
Altered response to histamine in brain tumor vessels: the selective increase of regional cerebral blood flow in transplanted rat brain tumor.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cerebral Arte | 1993 |
Re-examination of [3H]mepyramine binding assay for histamine H1 receptor using quinine.
Topics: Animals; Binding, Competitive; Brain; Cattle; Cell Membrane; Glioma; Kinetics; Liver; Organ Specific | 1992 |