pyrilamine has been researched along with Glial Cell Tumors in 6 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Molecular events involved in the homologous desensitization of histamine-mediated signal transduction system in glioma cells are not well understood." | 7.79 | Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells. ( Tseng, CL; Wei, JW, 2013) |
| "Information related to histamine-induced cellular responses in C6 glioma cells through second messenger pathways has not been fully studied, especially the involvement of arachidonic acid (AA) metabolism." | 7.78 | Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms. ( Tseng, CL; Wei, JW, 2012) |
| " The effects of histamine receptor agonists and antagonists on phospholipid hydrolysis in rat-derived C6 glioma cells have been investigated." | 7.69 | Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP. ( Hill, SJ; Peakman, MC, 1994) |
| "Molecular events involved in the homologous desensitization of histamine-mediated signal transduction system in glioma cells are not well understood." | 3.79 | Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells. ( Tseng, CL; Wei, JW, 2013) |
| "Information related to histamine-induced cellular responses in C6 glioma cells through second messenger pathways has not been fully studied, especially the involvement of arachidonic acid (AA) metabolism." | 3.78 | Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms. ( Tseng, CL; Wei, JW, 2012) |
| " The effects of histamine receptor agonists and antagonists on phospholipid hydrolysis in rat-derived C6 glioma cells have been investigated." | 3.69 | Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP. ( Hill, SJ; Peakman, MC, 1994) |
| "The authors studied the effect of intracarotid administration of histamine on the regional cerebral blood flow (rCBF) in transplanted rat C6 glioma by the hydrogen clearance method." | 3.68 | Altered response to histamine in brain tumor vessels: the selective increase of regional cerebral blood flow in transplanted rat brain tumor. ( Fukui, M; Ikezaki, K; Natori, Y; Nomura, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tseng, CL | 2 |
| Wei, JW | 2 |
| Fujimoto, K | 2 |
| Horio, Y | 2 |
| Sugama, K | 1 |
| Ito, S | 1 |
| Liu, YQ | 2 |
| Fukui, H | 2 |
| Peakman, MC | 1 |
| Hill, SJ | 1 |
| Nomura, T | 1 |
| Ikezaki, K | 1 |
| Natori, Y | 1 |
| Fukui, M | 1 |
| Mizuguchi, H | 1 |
| Imamura, I | 1 |
| Abe, Y | 1 |
6 other studies available for pyrilamine and Glial Cell Tumors
| Article | Year |
|---|---|
Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells.
Topics: Animals; Arachidonic Acid; Brain Neoplasms; Calcium; Cell Line, Tumor; Glioma; Histamine; Inositol P | 2013 |
Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms.
Topics: Animals; Arachidonic Acid; Calcium; Cell Line, Tumor; Egtazic Acid; Glioma; Glycosylphosphatidylinos | 2012 |
Genomic cloning of the rat histamine H1 receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; DNA; Genomic Library; Gliom | 1993 |
Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP.
Topics: Animals; Cyclic AMP; Glioma; Histamine; Histamine Agonists; Histamine H1 Antagonists; Hydrolysis; Li | 1994 |
Altered response to histamine in brain tumor vessels: the selective increase of regional cerebral blood flow in transplanted rat brain tumor.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cerebral Arte | 1993 |
Re-examination of [3H]mepyramine binding assay for histamine H1 receptor using quinine.
Topics: Animals; Binding, Competitive; Brain; Cattle; Cell Membrane; Glioma; Kinetics; Liver; Organ Specific | 1992 |