pyrilamine has been researched along with Gastric Ulcer in 11 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment with combination of pyrilamine plus histamine caused an increase in gastric ulcer area and serum interleukin-1beta above the value observed in animals treated with saline, and this effect was accompanied by a decrease in gastric mucosal DNA synthesis." | 3.73 | Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats. ( Brzozowski, T; Ceranowicz, P; Dembiński, A; Dembiński, M; Konturek, SJ; Pawlik, WW; Warzecha, Z, 2005) |
| "The aetiology of reserpine-induced gastric ulcer formation and the antiulcer effects of solcoseryl were studied in rats." | 3.67 | A study on the aetiology of reserpine ulceration and the antiulcer action of solcoseryl in rat stomach. ( Cho, CH; Dai, S; Ogle, CW, 1985) |
| "The effects of atropine, mepyramine, metiamide or NaHCO3 on gastric ulceration, gastric secretion and gastric mast cell degranulation were studied in stressed pylorus-occluded rats." | 3.66 | Cholinergic-mediated gastric mast cell degranulation with subsequent histamine H1-and H2-receptor activation in stress ulceration in rats. ( Cho, CH; Ogle, CW, 1979) |
| " The inhibition was characterized by displacement of the dose-response to histamine to the right, in parallel, without depression of the maximum." | 1.27 | Actions of nizatidine on the rat uterus, dog stomach and experimentally induced gastric lesions. ( Evans, DC; Lin, TM; Ruffolo, RR; Warrick, MW, 1986) |
| "Gastric mucosal lesions were produced in rats by dosing orally with aspirin, 300 mg/kg." | 1.26 | H2-receptor antagonists protect against aspirin-induced gastric lesions in the rat. ( Bunce, KT; Daly, MJ; Humphray, JM; Stables, R, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dembiński, A | 1 |
| Warzecha, Z | 1 |
| Ceranowicz, P | 1 |
| Brzozowski, T | 1 |
| Dembiński, M | 1 |
| Konturek, SJ | 1 |
| Pawlik, WW | 1 |
| Bunce, KT | 1 |
| Daly, MJ | 1 |
| Humphray, JM | 1 |
| Stables, R | 1 |
| Del Soldato, P | 1 |
| Tanaka, S | 1 |
| Akiba, Y | 1 |
| Kaunitz, JD | 1 |
| Bommelaer, G | 1 |
| Guth, PH | 1 |
| Brown, PA | 1 |
| Brown, TH | 1 |
| Vernikos-Danellis, J | 1 |
| Cho, CH | 3 |
| Ogle, CW | 3 |
| Mølster, A | 1 |
| Svanes, K | 1 |
| Raugstad, TS | 1 |
| Søreide, O | 1 |
| Dai, S | 1 |
| Lin, TM | 1 |
| Evans, DC | 1 |
| Warrick, MW | 1 |
| Ruffolo, RR | 1 |
11 other studies available for pyrilamine and Gastric Ulcer
| Article | Year |
|---|---|
Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats.
Topics: Animals; Capsaicin; DNA; Gastric Mucosa; Histamine; Histamine Antagonists; Histamine H1 Antagonists; | 2005 |
H2-receptor antagonists protect against aspirin-induced gastric lesions in the rat.
Topics: Animals; Aspirin; Cimetidine; Female; Furans; Gastric Mucosa; Histamine H2 Antagonists; Pyrilamine; | 1981 |
Studies with specific agonists and antagonists of the role of histamine H1- and H2-receptor activation in the pathogenesis of gastric lesions in rats.
Topics: Aminopyridines; Animals; Atropine; Dimaprit; Drug Interactions; Female; Histamine; Pyridines; Pyrila | 1984 |
Pentagastrin gastroprotection against acid is related to H2 receptor activation but not acid secretion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Gastric Acid; Gastric | 1998 |
Protection by histamine receptor antagonists and prostaglandin against gastric mucosal barrier disruption in the rat.
Topics: Administration, Topical; Animals; Aspirin; Cimetidine; Drug Combinations; Gastric Juice; Gastric Muc | 1979 |
Histamine H2 receptor: involvement in gastric ulceration.
Topics: Animals; Aspirin; Corticosterone; Female; Histamine; Histamine H1 Antagonists; Histamine Release; Me | 1976 |
Cholinergic-mediated gastric mast cell degranulation with subsequent histamine H1-and H2-receptor activation in stress ulceration in rats.
Topics: Animals; Atropine; Bicarbonates; Dexamethasone; Male; Mast Cells; Metiamide; Parasympathetic Nervous | 1979 |
Histamine H1- and H2-receptor-mediated gastric microcirculatory effects in the aetiology of stress ulceration in the rat stomach.
Topics: Aminopyridines; Animals; Dose-Response Relationship, Drug; Gastric Mucosa; Humans; Male; Mast Cells; | 1978 |
Release of inflammatory mediators into the gastric wall of rats with acute acetic acid induced ulcer.
Topics: Acetates; Acute Disease; Animals; Capillary Permeability; Gastric Mucosa; Gastritis; Indomethacin; M | 1978 |
A study on the aetiology of reserpine ulceration and the antiulcer action of solcoseryl in rat stomach.
Topics: Actihaemyl; Animals; Anti-Ulcer Agents; Atropine; Cimetidine; Gastric Acid; Histamine Release; Male; | 1985 |
Actions of nizatidine on the rat uterus, dog stomach and experimentally induced gastric lesions.
Topics: Animals; Aspirin; Atropine; Dogs; Duodenum; Female; Gastrointestinal Motility; Guanidines; Guinea Pi | 1986 |