pyrilamine has been researched along with Facial Pain in 2 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Facial Pain: Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study explored the interaction between histaminergic and opioidergic systems at the level of the hippocampus in modulation of orofacial pain by intra-hippocampal microinjections of histamine, pyrilamine (an antagonist of histamine H(1) receptors), ranitidine (an antagonist of histamine H(2) receptors), morphine (an opioid receptor agonist) and naloxone (an opioid receptor antagonist) in separate and combined treatments." | 7.77 | Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats. ( Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E, 2011) |
| "The present study explored the interaction between histaminergic and opioidergic systems at the level of the hippocampus in modulation of orofacial pain by intra-hippocampal microinjections of histamine, pyrilamine (an antagonist of histamine H(1) receptors), ranitidine (an antagonist of histamine H(2) receptors), morphine (an opioid receptor agonist) and naloxone (an opioid receptor antagonist) in separate and combined treatments." | 3.77 | Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats. ( Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E, 2011) |
| " In the present study, the effect of microinjection of histamine, mepyramine (a histamine H(1) receptor antagonist) and ranitidine (a histamine H(2) receptor antagonist) into the dorsal hippocampus was investigated on a model of orofacial pain in rats." | 3.76 | Effect of microinjection of histamine into the dorsal hippocampus on the orofacial formalin-induced pain in rats. ( Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erfanparast, A | 2 |
| Tamaddonfard, E | 2 |
| Farshid, AA | 2 |
| Khalilzadeh, E | 2 |
2 other studies available for pyrilamine and Facial Pain
| Article | Year |
|---|---|
Effect of microinjection of histamine into the dorsal hippocampus on the orofacial formalin-induced pain in rats.
Topics: Analgesics; Animals; Behavior, Animal; Facial Pain; Formaldehyde; Hippocampus; Histamine; Histamine | 2010 |
Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Facial Pain; Formaldehyde; Hippocampus; Histami | 2011 |