pyrilamine has been researched along with Experimental Neoplasms in 3 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine treatment accelerated tumor growth, but only in normal animals and had little effect on tumor growth in immunocompromised hosts." | 5.27 | The effect of histamine, antihistamines, and a mast cell stabilizer on the growth of cloudman melanoma cells in DBA/2 mice. ( Askenase, PW; Nordlund, JJ, 1983) |
| " This toxic response could be passively transferred with serum, indicating that it was due to formation of immune complexes or to their subsequent clearance." | 1.28 | Toxicity associated with the formation and clearance of immune complexes between antitumour monoclonal antibodies and syngeneic anti-idiotypic antibodies in mice. ( Gribben, SJ; Pimm, MV, 1992) |
| "Histamine treatment accelerated tumor growth, but only in normal animals and had little effect on tumor growth in immunocompromised hosts." | 1.27 | The effect of histamine, antihistamines, and a mast cell stabilizer on the growth of cloudman melanoma cells in DBA/2 mice. ( Askenase, PW; Nordlund, JJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nordlund, JJ | 1 |
| Askenase, PW | 1 |
| Pimm, MV | 1 |
| Gribben, SJ | 1 |
| Habs, M | 1 |
| Shubik, P | 1 |
| Eisenbrand, G | 1 |
3 other studies available for pyrilamine and Experimental Neoplasms
| Article | Year |
|---|---|
The effect of histamine, antihistamines, and a mast cell stabilizer on the growth of cloudman melanoma cells in DBA/2 mice.
Topics: Animals; Chromones; Cimetidine; Histamine; Histamine Antagonists; Immunosuppression Therapy; Male; M | 1983 |
Toxicity associated with the formation and clearance of immune complexes between antitumour monoclonal antibodies and syngeneic anti-idiotypic antibodies in mice.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antigen-Antibody Complex; Antigens, Neo | 1992 |
Carcinogenicity of methapyrilene hydrochloride, mepyramine hydrochloride, thenyldiamine hydrochloride, and pyribenzamine hydrochloride in Sprague-Dawley rats.
Topics: Adenoma; Adrenal Gland Neoplasms; Aminopyridines; Animals; Dose-Response Relationship, Drug; Female; | 1986 |