pyrilamine has been researched along with Crohn Disease in 1 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine pretreatment of non-IBD control tissues reduced anti-IgE responses to levels seen in IBD colon but had no effect in small intestine." | 1.30 | Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease. ( Crowe, SE; Luthra, GK; Perdue, MH, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crowe, SE | 1 |
| Luthra, GK | 1 |
| Perdue, MH | 1 |
1 other study available for pyrilamine and Crohn Disease
| Article | Year |
|---|---|
Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease.
Topics: Animals; Antibodies, Anti-Idiotypic; Colforsin; Colitis, Ulcerative; Crohn Disease; Histamine; Hista | 1997 |