pyrilamine has been researched along with Cardiomegaly in 1 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dose-response (D-R) curves for histamine (H) in the HT group shifted leftward and upward as compared with the sham-operated (S) group." | 1.28 | Effect of histamine on isolated working guinea pig heart with left ventricular hypertrophy produced by pressure overload. ( Guo, ZG; Luo, WS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, WS | 1 |
| Guo, ZG | 1 |
1 other study available for pyrilamine and Cardiomegaly
| Article | Year |
|---|---|
Effect of histamine on isolated working guinea pig heart with left ventricular hypertrophy produced by pressure overload.
Topics: Animals; Cardiomegaly; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Heart Function Tes | 1989 |