pyrilamine has been researched along with Cardiac Hypertrophy in 1 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dose-response (D-R) curves for histamine (H) in the HT group shifted leftward and upward as compared with the sham-operated (S) group." | 1.28 | Effect of histamine on isolated working guinea pig heart with left ventricular hypertrophy produced by pressure overload. ( Guo, ZG; Luo, WS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, WS | 1 |
| Guo, ZG | 1 |
1 other study available for pyrilamine and Cardiac Hypertrophy
| Article | Year |
|---|---|
Effect of histamine on isolated working guinea pig heart with left ventricular hypertrophy produced by pressure overload.
Topics: Animals; Cardiomegaly; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Heart Function Tes | 1989 |