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pyrilamine and Bronchial Spasm

pyrilamine has been researched along with Bronchial Spasm in 20 studies

Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.

Research Excerpts

ExcerptRelevanceReference
" To determine which mediators are involved in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitised Brown Norway rats we investigated the effect of a histamine H(1) receptor antagonist, mepyramine, a 5-HT receptor antagonist, methysergide, and a cys-leukotriene-1 receptor antagonist, montelukast."7.71Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. ( Belvisi, MG; Birrell, MA; Foster, ML; Hele, DJ; Webber, SE, 2001)
" To determine which mediators are involved in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitised Brown Norway rats we investigated the effect of a histamine H(1) receptor antagonist, mepyramine, a 5-HT receptor antagonist, methysergide, and a cys-leukotriene-1 receptor antagonist, montelukast."3.71Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. ( Belvisi, MG; Birrell, MA; Foster, ML; Hele, DJ; Webber, SE, 2001)
"Bronchospasm is a well recognized adverse reaction to radiographic contrast media (RCM) and may occur more frequently in asthmatics and atopics."1.30The effect of antihistamine, endothelin antagonist and corticosteroid prophylaxis on contrast media induced bronchospasm. ( Emery, CJ; Laude, EA; Morcos, SK; Suvarna, SK, 1999)
"FPL 55712 was nonselective since it inhibited prostaglandin D2 and histamine-induced bronchoconstriction as well as LTC4-induced bronchoconstriction."1.27Mediators of C5a-induced bronchoconstriction in the guinea pig. ( Bell, RL; Regal, JF, 1987)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199015 (75.00)18.7374
1990's4 (20.00)18.2507
2000's1 (5.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ross, WJ1
Harrison, RG1
Jolley, MR1
Neville, MC1
Todd, A1
Verge, JP1
Dawson, W1
Sweatman, WJ1
DUNLOP, DM1
HUNTER, RB1
HERXHEIMER, H2
BAHL, CP1
Nijkamp, FP1
Ramakers, AG1
Rossoni, G1
Omini, C1
Folco, GC1
Vigano, T1
Brunelli, G1
Berti, F1
Andersson, P1
Anderson, WH1
O'Donnell, M1
Simko, BA1
Welton, AF1
Schachter, EN1
Zuskin, E1
Rienzi, N1
Goswami, S1
Maayani, S1
Wan, AE1
Castranova, V1
Siegel, P1
Whitmer, M1
Mustajbegovic, J1
Laude, EA1
Emery, CJ1
Suvarna, SK1
Morcos, SK1
Hele, DJ1
Birrell, MA1
Webber, SE1
Foster, ML1
Belvisi, MG1
Watanabe, A2
Hayashi, H1
Billah, MM1
Chapman, RW1
Egan, RW1
Gilchrest, H1
Piwinski, JJ1
Sherwood, J1
Siegel, MI1
West, RE1
Kreutner, W1
Adolphson, RL1
Finkel, MP1
Robichaud, LJ1
Desquand, S2
Lefort, J3
Liu, FT1
Mencia-Huerta, JM1
Vargaftig, BB3
Lagente, V1
Cirino, M1
Kurachi, M1
Hongoh, K1
Aihara, H1
Lellouch-Tubiana, A1
Pfister, A1
Regal, JF1
Bell, RL1

Other Studies

20 other studies available for pyrilamine and Bronchial Spasm

ArticleYear
Antianaphylactic agents. 1. 2-(Acylamino)oxazoles.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:4

    Topics: Anaphylaxis; Animals; Bronchial Spasm; Capillary Permeability; Female; Guinea Pigs; Humans; In Vitro

1979
Aleudrine and anthisan in bronchial spasm.
    Lancet (London, England), 1948, May-29, Volume: 1, Issue:6509

    Topics: Bronchi; Bronchial Spasm; Pyrilamine; Spasm

1948
Aleudrine and anthisan in bronchial spasm.
    Lancet (London, England), 1948, Jun-12, Volume: 1, Issue:6511

    Topics: Bronchi; Bronchial Spasm; Humans; Pyrilamine; Spasm

1948
Aleudrine and anthisan in bronchial spasm.
    Lancet (London, England), 1948, May-01, Volume: 1, Issue:6505

    Topics: Adrenal Glands; Bronchi; Bronchial Spasm; Histamine; Pyrilamine; Spasm; Tissue Extracts

1948
Mepyramine in bronchospasm. A report of three cases.
    Journal of the Indian Medical Association, 1962, May-16, Volume: 38

    Topics: Anti-Allergic Agents; Bronchi; Bronchial Diseases; Bronchial Spasm; Disease; Histamine H1 Antagonist

1962
Prevention of anaphylactic bronchoconstriction by a lipoxygenase inhibitor.
    European journal of pharmacology, 1980, Mar-07, Volume: 62, Issue:1

    Topics: Anaphylaxis; Animals; Autacoids; Bronchial Spasm; Drug Interactions; Guinea Pigs; Lipoxygenase Inhib

1980
Bronchodilating activity of mequitazine.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 268, Issue:1

    Topics: Acetylcholine; Airway Resistance; Anaphylaxis; Animals; Aspirin; Atropine; Blood Pressure; Bronchial

1984
Effects of inhibitors of anaphylactic mediators in two models of bronchial anaphylaxis in anaesthetized guinea-pigs.
    British journal of pharmacology, 1982, Volume: 77, Issue:2

    Topics: Anaphylaxis; Anesthesia; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Immunoglobulin E; Immunog

1982
An in vivo model for measuring antigen-induced SRS-A-mediated bronchoconstriction and plasma SRS-A levels in the guinea-pig.
    British journal of pharmacology, 1983, Volume: 78, Issue:1

    Topics: Animals; Antigens; Bronchial Spasm; Guinea Pigs; Male; Ovalbumin; Pyrilamine; Respiration; SRS-A; Ti

1983
Effects of recycled paper dust extracts on isolated guinea pig trachea.
    Lung, 1998, Volume: 176, Issue:1

    Topics: Animals; Atropine; Bronchial Spasm; Bronchitis; Bronchoconstriction; Bronchodilator Agents; Calcium

1998
The effect of antihistamine, endothelin antagonist and corticosteroid prophylaxis on contrast media induced bronchospasm.
    The British journal of radiology, 1999, Volume: 72, Issue:863

    Topics: Airway Resistance; Animals; Anti-Inflammatory Agents; Bronchial Spasm; Contrast Media; Drug Evaluati

1999
Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats.
    British journal of pharmacology, 2001, Volume: 132, Issue:2

    Topics: Acetates; Animals; Anti-Asthmatic Agents; Bronchi; Bronchial Spasm; Capillary Permeability; Cyclopro

2001
Allergen-induced biphasic bronchoconstriction in rats.
    International archives of allergy and applied immunology, 1990, Volume: 93, Issue:1

    Topics: Airway Resistance; Allergens; Aminophylline; Animals; Bronchial Spasm; Chromones; Cromolyn Sodium; D

1990
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Hi

1990
CI-922--a novel, potent antiallergic compound--II. Activity in animal models of allergy.
    International journal of immunopharmacology, 1987, Volume: 9, Issue:1

    Topics: Anaphylaxis; Animals; Ascaris; Azoles; Bronchial Spasm; Cromolyn Sodium; Cross Reactions; Dogs; Hist

1987
Antigen-induced bronchopulmonary alterations in the guinea pig: a new model of passive sensitization mediated by mouse IgE antibodies.
    International archives of allergy and applied immunology, 1989, Volume: 89, Issue:1

    Topics: Animals; Blood Cell Count; Bronchial Spasm; Chromones; Dinitrophenols; Diterpenes; Female; Ginkgolid

1989
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
    International archives of allergy and applied immunology, 1988, Volume: 85, Issue:1

    Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic;

1988
Suppression of bronchial response to platelet activating factor following taurine administration.
    Advances in experimental medicine and biology, 1987, Volume: 217

    Topics: Animals; Bronchial Spasm; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Mice; Mice, In

1987
Interactions between granulocytes and platelets with the guinea-pig lung in passive anaphylactic shock. Correlations with PAF-acether-induced lesion.
    International archives of allergy and applied immunology, 1987, Volume: 83, Issue:2

    Topics: Anaphylaxis; Animals; Blood Platelets; Bronchial Spasm; Female; Granulocytes; Guinea Pigs; Lung; Mal

1987
Mediators of C5a-induced bronchoconstriction in the guinea pig.
    International archives of allergy and applied immunology, 1987, Volume: 84, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchial Spasm; Chromones; Complement C5; Guinea Pigs; H

1987