pyrilamine has been researched along with Brain Swelling in 4 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility that histamine plays a role in the formation of traumatic brain edema was investigated in the rat." | 7.67 | Role of histamine in traumatic brain edema. An experimental study in the rat. ( Chansouria, JP; Dey, PK; Mohanty, S; Olsson, Y; Sharma, HS; Singh, S, 1989) |
| "The possibility that histamine plays a role in the formation of traumatic brain edema was investigated in the rat." | 3.67 | Role of histamine in traumatic brain edema. An experimental study in the rat. ( Chansouria, JP; Dey, PK; Mohanty, S; Olsson, Y; Sharma, HS; Singh, S, 1989) |
| "Histamine has potent effects on cerebral blood vessels which include increased permeability and dilatation." | 1.29 | Effects of antihistaminics on experimental brain edema. ( Schilling, L; Wahl, M, 1994) |
| "In cimetidine-pretreated animals, the cerebral blood flow was significantly elevated and the plasma and brain 5-hydroxytryptamine (serotonin) levels were slightly but significantly reduced as compared with the untreated stressed group." | 1.28 | Histamine modulates heat stress-induced changes in blood-brain barrier permeability, cerebral blood flow, brain oedema and serotonin levels: an experimental study in conscious young rats. ( Cervos-Navarro, J; Dey, PK; Nyberg, F; Sharma, HS, 1992) |
| "Pretreatment with histamine H2 receptor antagonist cimetidine significantly reduced the extravasation of both the tracers and thwarted the increase of brain water content as compared to the untreated group." | 1.28 | Role of histamine in pathophysiology of heat stress in rats. ( Cervós-Navarro, J; Sharma, HS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schilling, L | 1 |
| Wahl, M | 1 |
| Sharma, HS | 3 |
| Nyberg, F | 1 |
| Cervos-Navarro, J | 2 |
| Dey, PK | 2 |
| Mohanty, S | 1 |
| Singh, S | 1 |
| Chansouria, JP | 1 |
| Olsson, Y | 1 |
4 other studies available for pyrilamine and Brain Swelling
| Article | Year |
|---|---|
Effects of antihistaminics on experimental brain edema.
Topics: Animals; Antioxidants; Benzothiazoles; Blood-Brain Barrier; Brain Edema; Dexamethasone; Freezing; Hi | 1994 |
Histamine modulates heat stress-induced changes in blood-brain barrier permeability, cerebral blood flow, brain oedema and serotonin levels: an experimental study in conscious young rats.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Cimetidine; Histamine; Hot Temperature; Male; Orga | 1992 |
Role of histamine in pathophysiology of heat stress in rats.
Topics: Animals; Blood-Brain Barrier; Body Water; Brain; Brain Edema; Cimetidine; Histamine; Hot Temperature | 1991 |
Role of histamine in traumatic brain edema. An experimental study in the rat.
Topics: Animals; Brain Edema; Brain Injuries; Cimetidine; Histamine; Male; Pyrilamine; Rats; Rats, Inbred St | 1989 |