pyrilamine has been researched along with Brain Ischemia in 5 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Focal cerebral ischemia for 2 h by occlusion of the right middle cerebral artery provoked severe brain infarction in the rat brain after 24 h." | 1.33 | Prevention of brain infarction by postischemic administration of histidine in rats. ( Adachi, N; Arai, T; Liu, K, 2005) |
| "Histidine was administered four times, immediately, 6, 24, and 48 h after reperfusion of blood flow (1000 mg/kg, i." | 1.32 | Alleviation of ischemic neuronal damage by postischemic loading with histidine in the rat striatum. ( Adachi, N; Arai, T; Liu, K, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, N | 4 |
| Liu, K | 3 |
| Arai, T | 3 |
| Hiraga, N | 1 |
| Nagaro, T | 1 |
| Oishi, R | 1 |
| Itano, Y | 1 |
| Yamada, T | 1 |
| Hirakawa, M | 1 |
| Saeki, K | 1 |
| Shibata, S | 1 |
| Watanabe, S | 1 |
5 other studies available for pyrilamine and Brain Ischemia
| Article | Year |
|---|---|
Alleviation of ischemic neuronal damage by postischemic loading with histidine in the rat striatum.
Topics: Animals; Brain Ischemia; Cell Count; Corpus Striatum; Drug Interactions; Functional Laterality; Hist | 2004 |
Prevention of brain infarction by postischemic administration of histidine in rats.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Functional Laterality; Histamine H1 Antagonists; Hi | 2005 |
Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains.
Topics: Animals; Antigens, CD; Brain Ischemia; CD4-Positive T-Lymphocytes; Cell Count; Drug Combinations; Hi | 2007 |
Aggravation of ischemic neuronal damage in the rat hippocampus by impairment of histaminergic neurotransmission.
Topics: Animals; Benzothiazoles; Brain Ischemia; Cell Death; Hippocampus; Histamine Agonists; Histamine H1 A | 1993 |
A neuroprotective effect of histamine H1 receptor antagonist on ischemia-induced decrease in 2-deoxyglucose uptake in rat hippocampal slices.
Topics: Animals; Brain Ischemia; Cimetidine; Deoxyglucose; Hippocampus; Histamine H1 Antagonists; Histamine | 1993 |