pyrilamine has been researched along with Bone Loss, Osteoclastic in 2 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of cimetidine on rat adjuvant arthritis (AA) and rat osteoclast differentiation were studied." | 3.72 | The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine. ( Nakamura, T; Ueno, K; Yamaura, K; Yano, S; Yonekawa, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamaura, K | 1 |
| Yonekawa, T | 1 |
| Nakamura, T | 1 |
| Yano, S | 1 |
| Ueno, K | 1 |
| Dobigny, C | 1 |
| Saffar, JL | 1 |
2 other studies available for pyrilamine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine.
Topics: Animals; Arthritis, Experimental; Bone Density; Bone Resorption; Cartilage, Articular; Cell Differen | 2003 |
H1 and H2 histamine receptors modulate osteoclastic resorption by different pathways: evidence obtained by using receptor antagonists in a rat synchronized resorption model.
Topics: Animals; Bone Resorption; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Degranulation; Cimetid | 1997 |