pyrilamine has been researched along with Benign Neoplasms, Brain in 7 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Molecular events involved in the homologous desensitization of histamine-mediated signal transduction system in glioma cells are not well understood." | 7.79 | Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells. ( Tseng, CL; Wei, JW, 2013) |
| "In human astrocytoma U373 MG cells that express histamine H1 receptors (180 +/- 6 fmol/mg protein) but not H2 or H3 receptors, histamine stimulated mitogenesis as assessed by [3H]-thymidine incorporation (173 +/- 2% of basal; EC50, 2." | 7.71 | Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells. ( Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE, 2001) |
| " Histamine (1 mM) induced an accumulation of inositol monophosphate ([3H]-IP1) in the U373 MG human astrocytoma cell line which increased with time in the presence of 30 mM Li+." | 7.69 | Calcium-dependence of histamine- and carbachol-induced inositol phosphate formation in human U373 MG astrocytoma cells: comparison with HeLa cells and brain slices. ( Arias-Montaño, JA; Berger, V; Young, JM, 1994) |
| "Molecular events involved in the homologous desensitization of histamine-mediated signal transduction system in glioma cells are not well understood." | 3.79 | Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells. ( Tseng, CL; Wei, JW, 2013) |
| "In human astrocytoma U373 MG cells that express histamine H1 receptors (180 +/- 6 fmol/mg protein) but not H2 or H3 receptors, histamine stimulated mitogenesis as assessed by [3H]-thymidine incorporation (173 +/- 2% of basal; EC50, 2." | 3.71 | Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells. ( Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE, 2001) |
| " Histamine (1 mM) induced an accumulation of inositol monophosphate ([3H]-IP1) in the U373 MG human astrocytoma cell line which increased with time in the presence of 30 mM Li+." | 3.69 | Calcium-dependence of histamine- and carbachol-induced inositol phosphate formation in human U373 MG astrocytoma cells: comparison with HeLa cells and brain slices. ( Arias-Montaño, JA; Berger, V; Young, JM, 1994) |
| "The authors studied the effect of intracarotid administration of histamine on the regional cerebral blood flow (rCBF) in transplanted rat C6 glioma by the hydrogen clearance method." | 3.68 | Altered response to histamine in brain tumor vessels: the selective increase of regional cerebral blood flow in transplanted rat brain tumor. ( Fukui, M; Ikezaki, K; Natori, Y; Nomura, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L | 1 |
| Kracht, J | 1 |
| Peng, S | 1 |
| Bernhardt, G | 1 |
| Buschauer, A | 1 |
| Tseng, CL | 1 |
| Wei, JW | 1 |
| Arias-Montaño, JA | 2 |
| Berger, V | 1 |
| Young, JM | 2 |
| Nomura, T | 1 |
| Ikezaki, K | 1 |
| Natori, Y | 1 |
| Fukui, M | 1 |
| Young, KW | 1 |
| Pinnock, RD | 1 |
| Gibson, WJ | 1 |
| Hernández-Angeles, A | 1 |
| Soria-Jasso, LE | 1 |
| Ortega, A | 1 |
| Ishikawa, R | 1 |
| Horio, S | 1 |
| Fukui, H | 1 |
7 other studies available for pyrilamine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine.
Topics: Animals; Brain Neoplasms; Fluorescent Dyes; Fura-2; Glioblastoma; Guinea Pigs; Histamine H1 Antagoni | 2003 |
Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells.
Topics: Animals; Arachidonic Acid; Brain Neoplasms; Calcium; Cell Line, Tumor; Glioma; Histamine; Inositol P | 2013 |
Calcium-dependence of histamine- and carbachol-induced inositol phosphate formation in human U373 MG astrocytoma cells: comparison with HeLa cells and brain slices.
Topics: Animals; Astrocytoma; Brain Chemistry; Brain Neoplasms; Calcium; Calcium Channel Blockers; Carbachol | 1994 |
Altered response to histamine in brain tumor vessels: the selective increase of regional cerebral blood flow in transplanted rat brain tumor.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cerebral Arte | 1993 |
Dual effects of histamine and substance P on intracellular calcium levels in human U373 MG astrocytoma cells: role of protein kinase C.
Topics: Animals; Astrocytoma; Brain Neoplasms; Calcium; Cerebellum; Colforsin; Cyclic AMP; Enzyme Inhibitors | 1998 |
Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells.
Topics: Astrocytoma; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Ac | 2001 |
Insulin-induced up-regulation of histamine H1-receptors.
Topics: Astrocytoma; Brain Neoplasms; Enzyme Activators; Histamine H1 Antagonists; Humans; Inositol Phosphat | 2002 |