pyrilamine has been researched along with Aura in 4 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| ", ip) indicate that the liver is the primary site of biotransformation of the compound, suggesting that both 22a and its metabolite(s) are active, compensating probably low bioavailability of the parent molecule." | 1.43 | Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. ( Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Waszkielewicz, AM | 1 |
| Gunia-Krzyżak, A | 1 |
| Powroźnik, B | 1 |
| Słoczyńska, K | 1 |
| Pękala, E | 1 |
| Walczak, M | 1 |
| Bednarski, M | 1 |
| Żesławska, E | 1 |
| Nitek, W | 1 |
| Marona, H | 1 |
| Fujii, Y | 1 |
| Tanaka, T | 1 |
| Harada, C | 1 |
| Hirai, T | 1 |
| Kamei, C | 1 |
| Nishida, N | 1 |
| Huang, ZL | 1 |
| Mikuni, N | 1 |
| Miura, Y | 1 |
| Urade, Y | 1 |
| Hashimoto, N | 1 |
| Chen, Z | 1 |
| Li, WD | 1 |
| Zhu, LJ | 1 |
| Shen, YJ | 1 |
| Wei, EQ | 1 |
4 other studies available for pyrilamine and Aura
| Article | Year |
|---|---|
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Dru | 2016 |
Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats.
Topics: Amygdala; Animals; Cetirizine; Diphenhydramine; Electroencephalography; Epilepsy; Histamine H1 Antag | 2003 |
Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylenetetrazol model.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Convulsants; Cortical Synchronization; Deep Brain Stimul | 2007 |
Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats.
Topics: Animals; Drug Synergism; Epilepsy; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histi | 2002 |