pyrilamine has been researched along with Atopic Hypersensitivity in 19 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine and LTD4 were additive in terms of cutaneous microvascular permeability." | 1.28 | Interactive effects of peptidoleukotrienes and histamine on microvascular permeability and their involvement in experimental cutaneous and conjunctival immediate hypersensitivity. ( Gary, RK; Gleason, JG; Nieves, AL; Wasserman, MA; Williams, LS; Woodward, DF, 1989) |
| "In conjunctival immediate hypersensitivity, neither cimetidine nor pyrilamine alone produced an inhibitory effect, but a cimetidine-pyrilamine combination caused a significant reduction in the number of infiltrating eosinophils and prevented epithelial damage and goblet cell depletion." | 1.27 | Conjunctival eosinophil infiltration evoked by histamine and immediate hypersensitivity. Modification by H1- and H2-receptor blockade. ( Hawley, SB; Nieves, AL; Spada, CS; Woodward, DF, 1986) |
| "Cetirizine also inhibited the immediate hypersensitivity reaction induced by Ascaris extract in dogs." | 1.27 | Inhibition of histamine and allergen skin wheal by cetirizine in four animal species. ( Baltes, E; De Vos, C; Gobert, J; Maleux, MR, 1987) |
| " The dose-response curve of egg albumin on the trachea was shifted to the right." | 1.26 | Decreased Schultz-Dale reaction in airways from sensitized guinea pigs treated with threshold concentrations of egg albumin in vivo. ( Andersson, RG; Hedman, SE, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gibbs, CJ | 1 |
| Coutts, II | 1 |
| Jackson, SM | 1 |
| White, RJ | 1 |
| Binta, MG | 1 |
| Cunningham, MP | 1 |
| Mushi, EZ | 1 |
| Smith, H | 1 |
| Ross, JW | 1 |
| Spicer, BA | 1 |
| Sambyal, DS | 1 |
| Singh, IP | 1 |
| Yanni, JM | 1 |
| Smith, WL | 1 |
| Callaham, EM | 1 |
| Foxwell, MH | 1 |
| Alphin, RS | 1 |
| Hedman, SE | 1 |
| Andersson, RG | 1 |
| Grönneberg, R | 1 |
| Strandberg, K | 1 |
| Stålenheim, G | 1 |
| Zetterström, O | 1 |
| O'Malley, KE | 1 |
| Sloan, T | 1 |
| Joyce, P | 1 |
| Baird, AW | 3 |
| Akar, F | 1 |
| Saarinen, JV | 1 |
| Harvima, RJ | 1 |
| Horsmanheimo, M | 1 |
| Harvima, IT | 1 |
| Willadsen, P | 1 |
| Wood, GM | 1 |
| Riding, GA | 1 |
| Musoke, AJ | 1 |
| Williams, JF | 1 |
| Leid, RW | 1 |
| Baldo, BA | 1 |
| Fletcher, TC | 1 |
| Woodward, DF | 3 |
| Nieves, AL | 3 |
| Williams, LS | 1 |
| Gary, RK | 1 |
| Wasserman, MA | 1 |
| Gleason, JG | 1 |
| Spada, CS | 1 |
| Hawley, SB | 1 |
| Ledgard, SE | 1 |
| De Vos, C | 1 |
| Maleux, MR | 1 |
| Baltes, E | 1 |
| Gobert, J | 1 |
| Cuthbert, AW | 2 |
| MacVinish, LJ | 1 |
| Pearce, FL | 1 |
3 trials available for pyrilamine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Skin test wheal size and erythema not reduced by topical antihistamine.
Topics: Administration, Topical; Aminopyridines; Clinical Trials as Topic; Double-Blind Method; Erythema; Hi | 1983 |
Effect in man of anti-allergic drugs on the immediate and late phase cutaneous allergic reactions induced by anti-IgE.
Topics: Adolescent; Adult; Animals; Antigen-Antibody Reactions; Betamethasone; Humans; Hypersensitivity, Imm | 1981 |
Modulation of the immediate allergic wheal reaction in the skin by drugs inhibiting the effects of leukotriene C4 and prostaglandin D2.
Topics: Administration, Cutaneous; Adolescent; Adult; Allergens; Animals; Anti-Allergic Agents; Cattle; Cycl | 2001 |
16 other studies available for pyrilamine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Effect of some drugs on the skin response of tick-resistant cattle to an allergenic extract of larval Rhipicephalus appendiculatus.
Topics: Animals; Aspirin; Cattle; Cattle Diseases; Cyclophosphamide; Histamine; Histamine H1 Antagonists; Hy | 1984 |
Rat passive peritoneal anaphylaxis following sensitisation with guinea pig antiserum: an immediate hypersensitivity reaction without histamine release.
Topics: Anaphylaxis; Animals; Antigens; Blood Proteins; Coloring Agents; Cyproheptadine; Guinea Pigs; Histam | 1980 |
Cutaneous hypersensitivity in sheep injected with sheep pox virus soluble antigens.
Topics: Animals; Antigens, Viral; Histamine Release; Hypersensitivity, Immediate; Poxviridae; Pyrilamine; Sh | 1980 |
A method for measuring changes in tracheal mucus gel layer thickness as an indication of an immediate hypersensitivity response.
Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Atropine; Chromones; Cimetidine; Cromolyn Sodium; Dose- | 1984 |
Decreased Schultz-Dale reaction in airways from sensitized guinea pigs treated with threshold concentrations of egg albumin in vivo.
Topics: Animals; Female; Guinea Pigs; Histamine; Hypersensitivity, Immediate; Lung; Male; Muscle Contraction | 1982 |
Type I hypersensitivity reactions in intestinal mucosae from rats infected with Fasciola hepatica.
Topics: Acetylcholine; Analysis of Variance; Animals; Antigens, Helminth; Chlorine; Colon; Fascioliasis; Hyp | 1993 |
Endothelial reactivity to the immediate hypersensitivity reaction of guinea pig pulmonary artery.
Topics: Animals; Dicarboxylic Acids; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; E | 2000 |
The relation between skin histamine concentration, histamine sensitivity, and the resistance of cattle to the tick, Boophilus microplus.
Topics: Allergens; Animals; Cattle; Histamine; Hypersensitivity, Immediate; Pyrilamine; Skin; Ticks | 1979 |
Immunological response of the rat to infection with Taenia taeniaeformis. VI. The role of immediate hypersensitivity in resistance to reinfection.
Topics: Animals; Antibodies; Cyproheptadine; Histamine; Hypersensitivity, Immediate; Immunity, Maternally-Ac | 1978 |
Phylogenetic aspects of hypersensitivity: immediate hypersensitivity reactions in flatfish.
Topics: Animals; Antibody Formation; Biological Assay; Biological Evolution; Cromolyn Sodium; Diethylcarbama | 1975 |
Interactive effects of peptidoleukotrienes and histamine on microvascular permeability and their involvement in experimental cutaneous and conjunctival immediate hypersensitivity.
Topics: Animals; Capillary Permeability; Chromium Radioisotopes; Cimetidine; Conjunctiva; Dicarboxylic Acids | 1989 |
Conjunctival eosinophil infiltration evoked by histamine and immediate hypersensitivity. Modification by H1- and H2-receptor blockade.
Topics: Animals; Cell Movement; Cimetidine; Conjunctival Diseases; Eosinophils; Female; Guinea Pigs; Histami | 1986 |
Conjunctival immediate hypersensitivity: re-evaluation of histamine involvement in the vasopermeability response.
Topics: Albumins; Animals; Capillary Permeability; Cimetidine; Conjunctiva; Dimaprit; Dose-Response Relation | 1986 |
Inhibition of histamine and allergen skin wheal by cetirizine in four animal species.
Topics: Allergens; Animals; Benzhydryl Compounds; Cetirizine; Clemastine; Dogs; Female; Guinea Pigs; Histami | 1987 |
Type 1 hypersensitivity reactions in reconstructed tissues using syngeneic cell types.
Topics: Animals; Cells, Cultured; Electrophysiology; Epithelium; Guinea Pigs; Histamine; Hypersensitivity, I | 1987 |
Immediate hypersensitivity reactions in epithelia from rats infected with Nippostrongylus brasiliensis.
Topics: Animals; Chlorides; Chromones; Colon; Cromolyn Sodium; Electric Conductivity; Epithelium; Hypersensi | 1985 |