pyrilamine has been researched along with Arthritis, Rheumatoid in 3 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine H1 receptors have been demonstrated on adherent rheumatoid synovial cells using biochemical and radioligand binding assays in vitro." | 1.27 | Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists. ( Taylor, DJ; Woolley, DE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Permin, H | 1 |
| Skov, PS | 1 |
| Norn, S | 1 |
| Geisler, A | 1 |
| Klysner, R | 1 |
| Andersen, V | 1 |
| Wiik, A | 1 |
| Manthorpe, R | 1 |
| Nielsen, H | 1 |
| Petersen, J | 1 |
| Taylor, DJ | 2 |
| Woolley, DE | 2 |
3 other studies available for pyrilamine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Possible role of histamine in rheumatoid arthritis. Treatment with cimetidine and mepyramine.
Topics: Adolescent; Adult; Aminopyridines; Arthritis, Rheumatoid; Cimetidine; Drug Therapy, Combination; Fem | 1981 |
Evidence for both histamine H1 and H2 receptors on human articular chondrocytes.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Histamin | 1987 |
Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists.
Topics: Arthritis, Rheumatoid; Binding, Competitive; Cells, Cultured; Chlorpheniramine; Histamine; Histamine | 1987 |