pyrilamine has been researched along with Anxiety in 9 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we investigate the effects of the histaminergic system and cannabinoid receptor agents on anxiety-related behaviors and their interactions using the hole-board test on mice." | 7.76 | Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice. ( Bina, P; Nasehi, M; Piri, M; Zarrindast, MR, 2010) |
| "The central histaminergic system is known to have modulatory influence on anxiety-related behaviour both in animals and humans through histamine H1 and/or H2 receptors." | 7.74 | Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats. ( Rezayof, A; Rostami, P; Valizadegan, F; Zarrindast, MR, 2008) |
| "In the present study, we have investigated the effects and the interaction of the GABAergic and histaminergic systems in the basolateral amygdala (BLA) of rats using the plus-maze test of anxiety-like behaviors." | 7.74 | GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors. ( Hajizadeh Moghaddam, A; Heidary-Davishani, A; Roohbakhsh, A; Rostami, P; Zarrindast, MR, 2008) |
| "Reports indicate that histamine and histaminergic agents can change anxiety-related behaviours in both animals and humans." | 7.73 | The effects of histaminergic agents in the central amygdala of rats in the elevated plus-maze test of anxiety. ( Moghadam, AH; Roohbakhsh, A; Rostami, P; Zarrindast, MR, 2005) |
| "Histaminergic receptors and neuronal nitric oxide synthase (nNOS) are co-expressed at high levels in the hippocampal neurons and alter anxiety-like behaviors in rodents." | 3.78 | Influence of nitric oxide agents in the dorsal hippocampus of mice on anxiogenic-like effect induced by histamine. ( Asgariyan, M; Nasehi, M; Piri, M; Zarrindast, MR, 2012) |
| "In the present study, we investigate the effects of the histaminergic system and cannabinoid receptor agents on anxiety-related behaviors and their interactions using the hole-board test on mice." | 3.76 | Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice. ( Bina, P; Nasehi, M; Piri, M; Zarrindast, MR, 2010) |
| "In the present study, the influence of withdrawal from repeated administration of morphine on intra-ventral hippocampal microinjection of histamine-induced anxiety-like behavior was investigated in male Wistar rats." | 3.76 | Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection. ( Khodarahmi, P; Oryan, S; Rezayof, A; Zarrindast, MR, 2010) |
| "The central histaminergic system is known to have modulatory influence on anxiety-related behaviour both in animals and humans through histamine H1 and/or H2 receptors." | 3.74 | Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats. ( Rezayof, A; Rostami, P; Valizadegan, F; Zarrindast, MR, 2008) |
| "In the present study, we have investigated the effects and the interaction of the GABAergic and histaminergic systems in the basolateral amygdala (BLA) of rats using the plus-maze test of anxiety-like behaviors." | 3.74 | GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors. ( Hajizadeh Moghaddam, A; Heidary-Davishani, A; Roohbakhsh, A; Rostami, P; Zarrindast, MR, 2008) |
| "Reports indicate that histamine and histaminergic agents can change anxiety-related behaviours in both animals and humans." | 3.73 | The effects of histaminergic agents in the central amygdala of rats in the elevated plus-maze test of anxiety. ( Moghadam, AH; Roohbakhsh, A; Rostami, P; Zarrindast, MR, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zarrindast, MR | 7 |
| Nasehi, M | 2 |
| Piri, M | 2 |
| Bina, P | 1 |
| Khodarahmi, P | 1 |
| Rezayof, A | 2 |
| Oryan, S | 1 |
| Asgariyan, M | 1 |
| Moghadam, AH | 1 |
| Rostami, P | 4 |
| Roohbakhsh, A | 2 |
| Torabi, M | 1 |
| Fazli-Tabaei, S | 1 |
| Kumar, KV | 1 |
| Krishna, DR | 1 |
| Palit, G | 1 |
| Valizadegan, F | 1 |
| Hajizadeh Moghaddam, A | 1 |
| Heidary-Davishani, A | 1 |
| Yuzurihara, M | 1 |
| Ikarashi, Y | 1 |
| Ishige, A | 1 |
| Sasaki, H | 1 |
| Kuribara, H | 1 |
| Maruyama, Y | 1 |
9 other studies available for pyrilamine and Anxiety
| Article | Year |
|---|---|
Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice.
Topics: Animals; Anxiety; Benzoxazines; Exploratory Behavior; Hippocampus; Histamine; Histamine Antagonists; | 2010 |
Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Hippocampus; Histamine; Histamine Antagoni | 2010 |
Influence of nitric oxide agents in the dorsal hippocampus of mice on anxiogenic-like effect induced by histamine.
Topics: Animals; Anxiety; Arginine; CA1 Region, Hippocampal; Enzyme Inhibitors; Hippocampus; Histamine; Hist | 2012 |
The effects of histaminergic agents in the central amygdala of rats in the elevated plus-maze test of anxiety.
Topics: Amygdala; Animals; Anxiety; Histamine; Histamine Agents; Histamine H1 Antagonists; Histamine H2 Anta | 2005 |
The effects of histaminergic agents in the dorsal hippocampus of rats in the elevated plus-maze test of anxiety.
Topics: Animals; Anxiety; Hippocampus; Histamine; Male; Maze Learning; Motor Activity; Pyrilamine; Ranitidin | 2006 |
Histaminergic H1 receptors mediate L-histidine-induced anxiety in elevated plus-maze test in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzothiazoles; Diazepam; Dose-Response Relationship, Drug; H | 2007 |
Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats.
Topics: Animals; Anxiety; Behavior, Animal; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; M | 2008 |
GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug In | 2008 |
Effects of drugs acting as histamine releasers or histamine receptor blockers on an experimental anxiety model in mice.
Topics: Animals; Anxiety; Cimetidine; Disease Models, Animal; Histamine Antagonists; Histamine Release; Inje | 2000 |