pyrilamine has been researched along with Anesthesia in 13 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inhaled adenosine induces airway obstruction in asthmatic but not healthy subjects, a phenomenon that is also observed in various animal species when they are immunised to a relevant antigen, but which does not occur in naïve animals." | 3.73 | Mechanism of adenosine-induced airways obstruction in allergic guinea pigs. ( Boswell-Smith, V; Keir, S; Page, C; Spina, D, 2006) |
| " A maximally effective dose of LY53857 (1 mg/kg) produced larger shifts of the dose-response curves to serotonin, 5-methoxytryptamine and alpha-methyl-serotonin than did a maximally effective dose of ketanserin (1 mg/kg)." | 1.28 | A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig. ( Buckner, CK; Dea, D; Krell, RD; Liberati, N, 1991) |
| " Mepyramine alone displaced the histamine dose-response curve to the right." | 1.26 | Antagonism of vasodepressor and gastric secretory responses to histamine by the H2-receptor antagonists, ranitidine and cimetidine, in the anaesthetized dog. ( Daly, MJ; Humphray, JM; Stables, R, 1981) |
| "Ketotifen was three times more potent than mepyramine in inhibiting the histamine-induced increase in air overflow volume." | 1.26 | The modification by ketotifen of respiratory responses to histamine and antigen in guinea-pigs. ( Armour, C; Temple, DM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keir, S | 1 |
| Boswell-Smith, V | 1 |
| Spina, D | 1 |
| Page, C | 1 |
| Daly, MJ | 1 |
| Humphray, JM | 1 |
| Stables, R | 1 |
| Donoso, AO | 1 |
| Zárate, MB | 1 |
| Seltzer, A | 1 |
| Armour, C | 1 |
| Temple, DM | 1 |
| Andersson, P | 1 |
| Biggs, DF | 1 |
| Peterson, MA | 1 |
| Osborn, RR | 1 |
| Hay, DW | 1 |
| Wasserman, MA | 1 |
| Torphy, TJ | 1 |
| Perren, MJ | 1 |
| Feniuk, W | 1 |
| Humphrey, PP | 1 |
| Buckner, CK | 1 |
| Dea, D | 1 |
| Liberati, N | 1 |
| Krell, RD | 1 |
| Grundemar, L | 1 |
| Wahlestedt, C | 1 |
| Shen, GH | 1 |
| Zukowska-Grojec, Z | 1 |
| Håkanson, R | 1 |
| Morini, G | 1 |
| Chiavarini, M | 1 |
| Barocelli, E | 1 |
| Impicciatore, M | 1 |
| Daffonchio, L | 1 |
| Payne, AN | 1 |
| Lees, IW | 1 |
| Whittle, BJ | 1 |
| Jones, TR | 1 |
| Masson, P | 1 |
13 other studies available for pyrilamine and Anesthesia
| Article | Year |
|---|---|
Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor | 2006 |
Antagonism of vasodepressor and gastric secretory responses to histamine by the H2-receptor antagonists, ranitidine and cimetidine, in the anaesthetized dog.
Topics: Anesthesia; Animals; Blood Pressure; Cimetidine; Dogs; Dose-Response Relationship, Drug; Female; Fur | 1981 |
Histamine-induced prolactin release: pharmacological characterization of receptors in male rats.
Topics: Anesthesia; Animals; Furans; Histamine; Male; Methylhistamines; Metiamide; Prolactin; Pyrilamine; Ra | 1983 |
The modification by ketotifen of respiratory responses to histamine and antigen in guinea-pigs.
Topics: Aerosols; Airway Resistance; Anesthesia; Animals; Antigens; Cromolyn Sodium; Guinea Pigs; Histamine; | 1982 |
Effects of inhibitors of anaphylactic mediators in two models of bronchial anaphylaxis in anaesthetized guinea-pigs.
Topics: Anaphylaxis; Anesthesia; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Immunoglobulin E; Immunog | 1982 |
Comparison of the effects of histamine and serotonin on dynamic pulmonary compliance and pulmonary flow resistance in anesthetized guinea pigs.
Topics: Airway Resistance; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Guinea Pigs; Histamine; | 1979 |
SK&F 104353, a selective leukotriene receptor antagonist, inhibits leukotriene D4- and antigen-induced bronchoconstriction in cynomolgus monkeys.
Topics: Administration, Inhalation; Aerosols; Anesthesia; Animals; Antigens; Bronchoconstriction; Dicarboxyl | 1992 |
Vascular 5-HT1-like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5-HT1A or 5-HT1D subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Atropine; Carotid Arteries; Dogs; Gangl | 1991 |
A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig.
Topics: Anesthesia; Animals; Atropine; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Het | 1991 |
Biphasic blood pressure response to neuropeptide Y in anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Decerebrate State; Heart Rate; Injections, Intravenous; Male; N | 1990 |
Effects of H2-blockers on rat mesenteric arterioles under resting conditions.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Female; Histamine H2 Antagonists; Infusions, Intrav | 1989 |
Airway hyperreactivity follows anaphylactic microshock in anaesthetized guinea-pigs.
Topics: Acetylcholine; Administration, Inhalation; Anaphylaxis; Anesthesia; Animals; Guinea Pigs; Injections | 1989 |
Comparative study of the pulmonary effects of intravenous leukotrienes and other bronchoconstrictors in anaesthetized guinea pigs.
Topics: Airway Resistance; Anesthesia; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Blood Pressur | 1985 |