pyrilamine has been researched along with Anaphylaxis in 75 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combination therapy blocking both PAF and histamine markedly reduces the severity of peanut-induced anaphylaxis, and thus it may be a potential life-saving therapeutic approach in peanut and, likely, other food-induced anaphylaxis." | 7.75 | Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. ( Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S, 2009) |
| "To elucidate the role of histamine in each of these symptoms, we induced the passive systemic anaphylaxis reaction in histidine decarboxylase gene knockout (HDC [-/-]) mice, which lack histamine." | 7.71 | The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis. ( Adachi, T; Hori, Y; Ishigaki-Suzuki, S; Kagaya, Y; Kikuchi, Y; Makabe-Kobayashi, Y; Nagy, A; Ohtsu, H; Shirato, K; Takai, T; Ujike, A; Watanabe, T, 2002) |
| " A selective and potent 5-LO inhibitor, zileuton (N-1(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea, A-64077) was evaluated in models of airway anaphylaxis, where leukotrienes are a major component." | 7.69 | The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis. ( Bell, RL; Brooks, DW; Carter, GW; Malo, PE; Shaughnessy, TK; Summers, JB, 1994) |
| "The selective hetrazepinoic platelet-activating factor (PAF) antagonist WEB 2170 (Bepafant) was used to study the pathophysiological role of PAF in several models of anaphylaxis in mice and guinea pigs." | 7.68 | Effect of the hetrazepinoic platelet-activating factor antagonist Bepafant (WEB 2170) in models of active and passive anaphylaxis in mice and guinea pigs. ( Heuer, HO, 1991) |
| "Cardiac anaphylaxis was elicited in isolated working guinea pig hearts in the presence of the histamine receptor antagonists pyrilamine and cimetidine, adenosine or hydrocortisone." | 7.67 | Protective effects of histamine H1 and H2 antagonists, adenosine and hydrocortisone on cardiac anaphylaxis. ( Guo, ZG; Qiu, R, 1989) |
| "WEB 2086, a novel specific platelet activating factor (PAF) antagonist derived from triazolodiazepines, inhibited in a dose-related manner the PAF-dependent component of anaphylaxis as well as PAF-induced effects in mice and guinea pigs." | 7.67 | Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis. ( Casals-Stenzel, J, 1987) |
| "Tracheal smooth muscle (TSM) from an ovalbumin sensitized canine model of allergic asthma showed hypersensitivity and hyper-reactivity to histamine (H) when compared to that from littermate controls in vitro." | 7.66 | Histamine pharmacology in airway smooth muscle from a canine model of asthma. ( Antonissen, LA; Bergen, J; Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1980) |
| "Azelastine is an orally effective and long-acting inhibitor of in vivo synthesis and/or release of leukotrienes." | 5.27 | Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs. ( Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD, 1986) |
| "Combination therapy blocking both PAF and histamine markedly reduces the severity of peanut-induced anaphylaxis, and thus it may be a potential life-saving therapeutic approach in peanut and, likely, other food-induced anaphylaxis." | 3.75 | Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions. ( Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S, 2009) |
| "To elucidate the role of histamine in each of these symptoms, we induced the passive systemic anaphylaxis reaction in histidine decarboxylase gene knockout (HDC [-/-]) mice, which lack histamine." | 3.71 | The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis. ( Adachi, T; Hori, Y; Ishigaki-Suzuki, S; Kagaya, Y; Kikuchi, Y; Makabe-Kobayashi, Y; Nagy, A; Ohtsu, H; Shirato, K; Takai, T; Ujike, A; Watanabe, T, 2002) |
| " A selective and potent 5-LO inhibitor, zileuton (N-1(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea, A-64077) was evaluated in models of airway anaphylaxis, where leukotrienes are a major component." | 3.69 | The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis. ( Bell, RL; Brooks, DW; Carter, GW; Malo, PE; Shaughnessy, TK; Summers, JB, 1994) |
| "We have investigated the antigen-stimulated release of calcitonin gene-related peptide (CGRP) from ovalbumin-sensitized guinea-pig isolated hearts and the interaction with other mediators of anaphylaxis released concomitantly." | 3.69 | Release of calcitonin gene-related peptide in cardiac anaphylaxis. ( Amann, R; Donnerer, J; Peskar, BA; Schuligoi, R, 1997) |
| "The selective hetrazepinoic platelet-activating factor (PAF) antagonist WEB 2170 (Bepafant) was used to study the pathophysiological role of PAF in several models of anaphylaxis in mice and guinea pigs." | 3.68 | Effect of the hetrazepinoic platelet-activating factor antagonist Bepafant (WEB 2170) in models of active and passive anaphylaxis in mice and guinea pigs. ( Heuer, HO, 1991) |
| "Cardiac anaphylaxis was elicited in isolated working guinea pig hearts in the presence of the histamine receptor antagonists pyrilamine and cimetidine, adenosine or hydrocortisone." | 3.67 | Protective effects of histamine H1 and H2 antagonists, adenosine and hydrocortisone on cardiac anaphylaxis. ( Guo, ZG; Qiu, R, 1989) |
| "WEB 2086, a novel specific platelet activating factor (PAF) antagonist derived from triazolodiazepines, inhibited in a dose-related manner the PAF-dependent component of anaphylaxis as well as PAF-induced effects in mice and guinea pigs." | 3.67 | Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis. ( Casals-Stenzel, J, 1987) |
| "Tracheal smooth muscle (TSM) from an ovalbumin sensitized canine model of allergic asthma showed hypersensitivity and hyper-reactivity to histamine (H) when compared to that from littermate controls in vitro." | 3.66 | Histamine pharmacology in airway smooth muscle from a canine model of asthma. ( Antonissen, LA; Bergen, J; Kepron, W; Kroeger, EA; Mitchell, RW; Stephens, NL, 1980) |
| " 5 Specific doses of atropine, mepyramine (H1-blocker) and methysergide (5-HT antagonist) did not modify the anaphylactic reaction in coronary arteries, suggesting a negligible role for these biogenic amines." | 3.66 | Coronary anaphylaxis in vitro. ( Chand, N; Eyre, P, 1979) |
| "The effects of mepyramine, promethazine, chlorpromazine and lysergic acid diethylamide have been compared on the capillary permeability changes of the skin, produced by histamine, by 5-hydroxytryptamine and by passive cutaneous anaphylaxis in mice." | 3.64 | On the nature of the chemical mediators involved in anaphylactic reactions in mice. ( HALPERN, BN; NEVEU, T; SPECTOR, S, 1963) |
| "Treatment with dimaprit at 6 and 60 microM for 20 min significantly inhibited the anaphylactic histamine release, whereas betahistine at up to 80 microM under the same conditions did not affect it." | 1.29 | Dimaprit, a histamine H2-agonist, inhibits anaphylactic histamine release from mast cells and the decreased release is restored by thioperamide (H3-antagonist), but not by cimetidine (H2-antagonist). ( Kohno, S; Nabe, T; Ogawa, K; Ohata, K; Yamamura, H, 1993) |
| "Previous studies have shown that an anaphylactic reaction in the isolated perfused heart is characterized by drastic coronary constriction, arrhythmias, and severe impairment of contractility." | 1.28 | Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis. ( Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M, 1990) |
| "In propranolol-pretreated guinea-pigs the potentiation induced by gallamine 3 and 10 mumol kg-1 was inhibited by 40 and 46%, respectively." | 1.28 | Mechanism of the potentiation of neurally-induced bronchoconstriction by gallamine in the guinea-pig. ( Del Monte, M; Omini, C; Subissi, A, 1990) |
| "Ovalbumin was used to trigger passive systemic anaphylactic shock in guinea-pigs treated with serum provided by actively sensitized animals." | 1.27 | Failure of a combined anti-histamine and anti-leukotriene treatment to suppress passive anaphylaxis in the guinea-pig. ( Cordeiro, R; Garcez Do Carmo, L; Lagente, V; Lefort, J; Randon, J; Vargaftig, BB, 1986) |
| "Azelastine is an orally effective and long-acting inhibitor of in vivo synthesis and/or release of leukotrienes." | 1.27 | Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs. ( Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD, 1986) |
| "Indomethacin treatment was also ineffective." | 1.27 | Pharmacological analysis of the vascular permeability response in the anaphylactic phase of allergic inflammation in rats. ( Hirasawa, N; Ohuchi, K; Tsurufuji, S; Watanabe, M, 1985) |
| "Ketotifen is a compound with strong anti-anaphylactic and anti-histaminic properties both in experimental mental animals and man." | 1.26 | Dissociation between the anti-anaphylactic and the anti-histaminic actions of ketotifen. ( Baggiolini, M; Martin, U, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (70.67) | 18.7374 |
| 1990's | 17 (22.67) | 18.2507 |
| 2000's | 5 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ross, WJ | 1 |
| Harrison, RG | 1 |
| Jolley, MR | 1 |
| Neville, MC | 1 |
| Todd, A | 1 |
| Verge, JP | 1 |
| Dawson, W | 1 |
| Sweatman, WJ | 1 |
| Buckle, DR | 2 |
| Rockell, CJ | 1 |
| Smith, H | 3 |
| Spicer, BA | 3 |
| Outred, DJ | 1 |
| Arias, K | 1 |
| Baig, M | 1 |
| Colangelo, M | 1 |
| Chu, D | 1 |
| Walker, T | 1 |
| Goncharova, S | 1 |
| Coyle, A | 1 |
| Vadas, P | 1 |
| Waserman, S | 1 |
| Jordana, M | 1 |
| Makabe-Kobayashi, Y | 1 |
| Hori, Y | 1 |
| Adachi, T | 1 |
| Ishigaki-Suzuki, S | 1 |
| Kikuchi, Y | 1 |
| Kagaya, Y | 1 |
| Shirato, K | 1 |
| Nagy, A | 1 |
| Ujike, A | 1 |
| Takai, T | 1 |
| Watanabe, T | 1 |
| Ohtsu, H | 1 |
| Zhao, L | 1 |
| Ohtaki, Y | 1 |
| Yamaguchi, K | 1 |
| Matsushita, M | 1 |
| Fujita, T | 1 |
| Yokochi, T | 1 |
| Takada, H | 1 |
| Endo, Y | 1 |
| HALPERN, BN | 1 |
| NEVEU, T | 1 |
| SPECTOR, S | 1 |
| SMITH, WG | 1 |
| Nijkamp, FP | 1 |
| Ramakers, AG | 1 |
| Martin, U | 1 |
| Baggiolini, M | 1 |
| Ross, JW | 1 |
| Terasawa, M | 1 |
| Imayoshi, T | 1 |
| Goto, K | 1 |
| Bottomley, KM | 1 |
| Lewis, S | 1 |
| Rising, TJ | 1 |
| Steward, A | 1 |
| Chand, N | 5 |
| DeRoth, L | 2 |
| Woodward, DF | 1 |
| Wasserman, MA | 1 |
| Weichman, BM | 1 |
| Ufkes, JG | 1 |
| Ottenhof, M | 1 |
| Rossoni, G | 1 |
| Omini, C | 2 |
| Folco, GC | 1 |
| Vigano, T | 1 |
| Brunelli, G | 1 |
| Berti, F | 1 |
| Maurer, DR | 1 |
| Schor, J | 1 |
| Sielczak, M | 1 |
| Wanner, A | 1 |
| Abraham, WM | 1 |
| Andersson, P | 1 |
| Antonissen, LA | 1 |
| Mitchell, RW | 1 |
| Kroeger, EA | 1 |
| Kepron, W | 1 |
| Stephens, NL | 1 |
| Bergen, J | 1 |
| Mathison, R | 1 |
| Davison, JS | 1 |
| Kohno, S | 2 |
| Nakao, S | 1 |
| Ogawa, K | 2 |
| Yamamura, H | 2 |
| Nabe, T | 2 |
| Ohata, K | 2 |
| Malo, PE | 1 |
| Bell, RL | 1 |
| Shaughnessy, TK | 1 |
| Summers, JB | 1 |
| Brooks, DW | 1 |
| Carter, GW | 1 |
| Schuligoi, R | 1 |
| Amann, R | 1 |
| Donnerer, J | 1 |
| Peskar, BA | 1 |
| Kreis, ME | 2 |
| Müller, M | 1 |
| Zittel, TT | 1 |
| Glatzle, J | 1 |
| Grundy, D | 2 |
| Jiang, W | 1 |
| Eastwood, C | 1 |
| Kirkup, AJ | 1 |
| Humphrey, PP | 1 |
| Molls, M | 1 |
| Bernauer, W | 2 |
| Jones, DG | 1 |
| Kay, AB | 1 |
| Eyre, P | 4 |
| Miller, P | 1 |
| Church, MK | 1 |
| Holroyde, MC | 2 |
| Kaliner, M | 1 |
| Barrett-Bee, KJ | 1 |
| Green, LR | 1 |
| Allouche, G | 1 |
| Santais, MC | 1 |
| Foussard, C | 1 |
| Ruff, F | 1 |
| Parrot, JL | 1 |
| Mitchell, HW | 1 |
| Denborough, MA | 1 |
| Goadby, P | 1 |
| Little, MA | 1 |
| Sackeyfio, AC | 1 |
| Iwama, T | 1 |
| Shikada, K | 1 |
| Yamamoto, A | 1 |
| Sakashita, M | 1 |
| Hibi, M | 1 |
| Tanaka, S | 1 |
| Felix, SB | 2 |
| Baumann, G | 2 |
| Hashemi, T | 2 |
| Niemczyk, M | 2 |
| Ochsenfeld, G | 1 |
| Ahmad, Z | 2 |
| Shirani, S | 1 |
| Blömer, H | 1 |
| Berdel, WE | 1 |
| Nambu, F | 2 |
| Murakata, S | 1 |
| Shiraji, T | 1 |
| Omawari, N | 1 |
| Sawada, M | 1 |
| Okegawa, T | 1 |
| Kawasaki, A | 1 |
| Ikeda, S | 1 |
| Jancar, S | 1 |
| Sirois, MG | 1 |
| Carrier, J | 1 |
| Braquet, P | 2 |
| Sirois, P | 1 |
| Sakuma, Y | 1 |
| Muramoto, K | 1 |
| Harada, K | 1 |
| Katayama, S | 1 |
| Tsunoda, H | 1 |
| Katayama, K | 1 |
| Uchida, M | 1 |
| Imanishi, N | 1 |
| Sugasawa, T | 1 |
| Morooka, S | 1 |
| Heuer, HO | 2 |
| Nakagawa, T | 1 |
| Mizushima, Y | 1 |
| Ishii, A | 1 |
| Motoishi, M | 1 |
| Yui, Y | 1 |
| Shida, T | 1 |
| Miyamoto, T | 1 |
| Tarayre, JP | 1 |
| Aliaga, M | 1 |
| Barbara, M | 1 |
| Tisseyre, N | 1 |
| Vieu, S | 1 |
| Tisne-Versailles, J | 1 |
| Del Monte, M | 1 |
| Subissi, A | 1 |
| Creese, BR | 1 |
| Temple, DM | 1 |
| Adolphson, RL | 1 |
| Finkel, MP | 1 |
| Robichaud, LJ | 1 |
| Assem, ES | 1 |
| Abdullah, NA | 1 |
| Konno-Amano, S | 1 |
| Hirao, T | 1 |
| Kohno, H | 1 |
| Mori, H | 1 |
| Sato, Y | 1 |
| Sekardi, L | 1 |
| Friedberg, KD | 1 |
| Bertrand, C | 1 |
| Tschirhart, E | 1 |
| Landry, Y | 1 |
| Nolan, JC | 1 |
| Stephens, DJ | 1 |
| Proakis, AG | 1 |
| Leonard, CA | 1 |
| Johnson, DN | 1 |
| Kilpatrick, BF | 1 |
| Foxwell, MH | 1 |
| Yanni, JM | 1 |
| Heuer, H | 1 |
| Casals-Stenzel, J | 2 |
| Daffonchio, L | 1 |
| Payne, AN | 2 |
| Lees, IW | 1 |
| Whittle, BJ | 1 |
| Qiu, R | 1 |
| Guo, ZG | 1 |
| Garcez Do Carmo, L | 1 |
| Cordeiro, R | 1 |
| Lagente, V | 3 |
| Lefort, J | 4 |
| Randon, J | 2 |
| Vargaftig, BB | 4 |
| Lee, TH | 2 |
| Austen, KF | 2 |
| Leitch, AG | 2 |
| Israel, E | 2 |
| Robinson, DR | 2 |
| Lewis, RA | 2 |
| Corey, EJ | 2 |
| Drazen, JM | 2 |
| Ravalese, J | 1 |
| Nolan, K | 1 |
| Diamantis, W | 1 |
| Perhach, JL | 1 |
| Sofia, RD | 1 |
| Cirino, M | 1 |
| Desquand, S | 2 |
| de Nucci, G | 1 |
| Lellouch-Tubiana, A | 1 |
| Pfister, A | 1 |
| Ashida, Y | 1 |
| Nomura, M | 1 |
| Kuriki, H | 1 |
| Maki, Y | 1 |
| Vilain, B | 1 |
| Touvay, C | 1 |
| Ohuchi, K | 1 |
| Hirasawa, N | 1 |
| Watanabe, M | 1 |
| Tsurufuji, S | 1 |
1 trial available for pyrilamine and Anaphylaxis
| Article | Year |
|---|---|
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evalu | 1991 |
74 other studies available for pyrilamine and Anaphylaxis
| Article | Year |
|---|---|
Antianaphylactic agents. 1. 2-(Acylamino)oxazoles.
Topics: Anaphylaxis; Animals; Bronchial Spasm; Capillary Permeability; Female; Guinea Pigs; Humans; In Vitro | 1979 |
Studies on 1,2,3-triazoles. 13. (Piperazinylalkoxy) [1]benzopyrano[2,3-d]-1,2,3-triazol-9(1H)-ones with combined H1-antihistamine and mast cell stabilizing properties.
Topics: Anaphylaxis; Animals; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; | 1986 |
N-benzylpiperazino derivatives of 3-nitro-4-hydroxycoumarin with H1 antihistamine and mast cell stabilizing properties.
Topics: 4-Hydroxycoumarins; Anaphylaxis; Animals; Ascitic Fluid; Guinea Pigs; Histamine Antagonists; Histami | 1984 |
Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions.
Topics: Allergens; Anaphylaxis; Animals; Arachis; Cholera Toxin; Cimetidine; Disease Models, Animal; Drug Th | 2009 |
The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis.
Topics: Allergens; Anaphylaxis; Animals; Blood Pressure; Body Temperature; Cimetidine; Histamine; Histamine | 2002 |
LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement system.
Topics: Anaphylaxis; Animals; Blood Platelets; Complement Activation; Complement C4; Complement C5; Endotoxi | 2002 |
On the nature of the chemical mediators involved in anaphylactic reactions in mice.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Capillary Permeability; Chlorpromazine; Histamine; Hista | 1963 |
MODIFICATION OF ANAPHYLACTIC SHOCK BY MEPYRAMINE AND ETHANOLAMINE.
Topics: Amino Alcohols; Anaphylaxis; Animals; Anti-Allergic Agents; Ascorbic Acid; Ethanolamine; Ethanolamin | 1965 |
Prevention of anaphylactic bronchoconstriction by a lipoxygenase inhibitor.
Topics: Anaphylaxis; Animals; Autacoids; Bronchial Spasm; Drug Interactions; Guinea Pigs; Lipoxygenase Inhib | 1980 |
Dissociation between the anti-anaphylactic and the anti-histaminic actions of ketotifen.
Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Clemastine; Female; Histamine H1 Antagonists; Ket | 1981 |
Rat passive peritoneal anaphylaxis following sensitisation with guinea pig antiserum: an immediate hypersensitivity reaction without histamine release.
Topics: Anaphylaxis; Animals; Antigens; Blood Proteins; Coloring Agents; Cyproheptadine; Guinea Pigs; Histam | 1980 |
[Effect of traxanox sodium on SRS-A release in bronchial and peritoneal anaphylaxis].
Topics: Anaphylaxis; Animals; Bronchi; Chromones; Cromolyn Sodium; Female; Guinea Pigs; Histamine H1 Antagon | 1983 |
A new in vivo method for the measurement of repetitive anaphylactic responses in the guinea-pig.
Topics: Albuterol; Anaphylaxis; Animals; Antibodies; Cromolyn Sodium; Dimaprit; Guinea Pigs; Male; Pyrilamin | 1984 |
Acute systemic anaphylaxis in adult domestic fowl: evidence for the protective role of H2-histaminergic and beta 2-adrenergic receptors.
Topics: Anaphylaxis; Animals; Blood Pressure; Carotid Arteries; Chickens; Chromones; Cimetidine; Dimaprit; E | 1980 |
Investigation of leukotriene involvement in the vasopermeability response associated with guinea pig tracheal anaphylaxis: comparison with cutaneous anaphylaxis.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromium Radioisotopes; Chromones; Female; Guinea Pigs | 1983 |
Characterization of various antiallergic agents using a new method for inducing systemic anaphylaxis in the rat.
Topics: Anaphylaxis; Animals; Blood Pressure; Bronchodilator Agents; Chromones; Cromolyn Sodium; Disease Mod | 1984 |
Bronchodilating activity of mequitazine.
Topics: Acetylcholine; Airway Resistance; Anaphylaxis; Animals; Aspirin; Atropine; Blood Pressure; Bronchial | 1984 |
Ciliary motility in airway anaphylaxis.
Topics: Anaphylaxis; Animals; Ascaris; Cilia; Cromolyn Sodium; Kinetics; Movement; Pyrilamine; Sheep; Trache | 1982 |
Effects of inhibitors of anaphylactic mediators in two models of bronchial anaphylaxis in anaesthetized guinea-pigs.
Topics: Anaphylaxis; Anesthesia; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Immunoglobulin E; Immunog | 1982 |
Histamine pharmacology in airway smooth muscle from a canine model of asthma.
Topics: Airway Resistance; Anaphylaxis; Animals; Asthma; Dogs; Histamine; In Vitro Techniques; Methylhistami | 1980 |
Capsaicin sensitive nerves in the jejunum of Nippostrongylus brasiliensis-sensitized rats participate in a cardiovascular depressor reflex.
Topics: Anaphylaxis; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Diterpenes; Ginkgolides; Guanethi | 1993 |
Possible participation of histamine H3-receptors in the regulation of anaphylactic histamine release from isolated rat peritoneal mast cells.
Topics: Anaphylaxis; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cimetidine; Dimaprit; D | 1994 |
Dimaprit, a histamine H2-agonist, inhibits anaphylactic histamine release from mast cells and the decreased release is restored by thioperamide (H3-antagonist), but not by cimetidine (H2-antagonist).
Topics: Anaphylaxis; Animals; Anticonvulsants; Betahistine; Cimetidine; Dimaprit; Histamine H2 Antagonists; | 1993 |
The 5-lipoxygenase inhibitory activity of zileuton in in vitro and in vivo models of antigen-induced airway anaphylaxis.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoconstriction; Disease Models, | 1994 |
Release of calcitonin gene-related peptide in cardiac anaphylaxis.
Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Calcitonin Gene-Related Peptide; Cimetidine; Cor | 1997 |
Mediators of neuronal activation in the rat brainstem following intestinal anaphylaxis.
Topics: Anaphylaxis; Animals; Brain Stem; Chickens; Histamine H1 Antagonists; Immunohistochemistry; Indometh | 2000 |
5-HT(3) and histamine H(1) receptors mediate afferent nerve sensitivity to intestinal anaphylaxis in rats.
Topics: Anaphylaxis; Animals; Carbolines; Electrophysiology; Histamine H1 Antagonists; Intestinal Diseases; | 2000 |
Influence of adrenaline, dibenamine and dopamine on acidosis, hemoconcentration and lethality in protracted anaphylactic shock of guinea-pigs.
Topics: Acidosis; Anaphylaxis; Animals; Dibenzylchlorethamine; Dopamine; Epinephrine; Female; Guinea Pigs; H | 1976 |
Chemotactic activity of guinea pig eosinophils for the ECF-A acidic tetrapeptides, histamine, histamine metabolites, and the effect of H1- and H2-receptor antagonists.
Topics: Alanine; Anaphylaxis; Animals; Burimamide; Chemotaxis, Leukocyte; Dose-Response Relationship, Immuno | 1977 |
Pharmacology of Schultz-Dale reaction in canine lung strip in vitro: possible model for allergic asthma.
Topics: Anaphylaxis; Animals; Asthma; Autacoids; Disease Models, Animal; Dogs; Female; Histamine H1 Antagoni | 1979 |
Sequential release of histamine and 5-hydroxytryptamine during pinnal anaphylaxis in the mouse.
Topics: Anaphylaxis; Ear; Histamine Release; Methysergide; Pyrilamine; Serotonin; Skin; Time Factors | 1976 |
Histamine enhances anaphylactic histamine release from bovine lung and leukocytes via histamine H2-receptor.
Topics: Anaphylaxis; Animals; Cattle; Granulocytes; Histamine; Histamine Release; In Vitro Techniques; Leuko | 1978 |
Human lung tissue and anaphylaxis:cyclic nucleotide response and prostaglandin synthesis.
Topics: Anaphylaxis; Cell Communication; Cyclic AMP; Cyclic GMP; Diphenhydramine; Histamine; Histamine Relea | 1979 |
The relationship between prostaglandin release and lung c-AMP levels during anaphylaxis in the guinea-pig.
Topics: Anaphylaxis; Animals; Burimamide; Cyclic AMP; Guinea Pigs; Histamine; Immunization; Indomethacin; Is | 1975 |
Role of H2-receptor antagonists in the feedback of histamine [proceedings].
Topics: Amine Oxidase (Copper-Containing); Anaphylaxis; Animals; Burimamide; Cyclic AMP; Feedback; Guinea Pi | 1977 |
Reactivity of isolated bovine mesenteric and hepatic veins to vasoactive agents and specific antigen.
Topics: Acetylcholine; Anaphylaxis; Animals; Antigens; Atropine; Cattle; Dopamine; Dose-Response Relationshi | 1975 |
Anaphylaxis in guinea-pig peripheral airways in vitro.
Topics: Anaphylaxis; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Isoproteren | 1979 |
In vitro anaphylaxis in guinea-pig lung: evidence for the protective role of histamine H2-receptors.
Topics: Anaphylaxis; Animals; Female; In Vitro Techniques; Lung; Male; Metiamide; Mice; Ovalbumin; Pyrilamin | 1979 |
Coronary anaphylaxis in vitro.
Topics: Anaphylaxis; Animals; Atropine; Carbachol; Cattle; Coronary Vessels; Histamine; In Vitro Techniques; | 1979 |
Release of creatine kinase by antigen, histamine, and catecholamines.
Topics: Anaphylaxis; Animals; Antigens; Catecholamines; Creatine Kinase; Dibenzylchlorethamine; Epinephrine; | 1976 |
The action of metiamide in anaphylaxis in vivo in the guinea-pig [proceedings].
Topics: Anaphylaxis; Animals; Guinea Pigs; Lung Volume Measurements; Metiamide; Pyrilamine; Thiourea | 1976 |
Proceedings: A comparison of the histopathological effects of anaphylatoxin (AT) and prostaglandins E2 (PGE2) and F2alpha (PGF2alpha) in guinea-pig lungs.
Topics: Anaphylaxis; Animals; Complement System Proteins; Guinea Pigs; Histamine; Lung; Peptide Fragments; P | 1975 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Anim | 1992 |
Effects of histamine H1-receptor blockade on respiratory and cardiac manifestation of systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Blood Gas Analysis; Electrocardiography; Female; Guinea Pigs; Heart; Heart Ven | 1991 |
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; El | 1990 |
OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Acrylates; Anaphylaxis; Animals; Bordetella pertussis; Cyclooxygenase | 1990 |
PAF induces rat plasma extravasation and releases eicosanoids during anaphylaxis.
Topics: Anaphylaxis; Animals; Blood Proteins; Capillary Permeability; Diterpenes; Eicosanoids; Ginkgolides; | 1991 |
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mic | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationshi | 1991 |
Effect of the hetrazepinoic platelet-activating factor antagonist Bepafant (WEB 2170) in models of active and passive anaphylaxis in mice and guinea pigs.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Lung; Male; Mice; Mice, Inbred Strains; | 1991 |
Pharmacological modulation of a model of bronchial inflammation after aerosol-induced active anaphylactic shock in conscious guinea pigs.
Topics: Albuterol; Anaphylaxis; Animals; Asthma; Bronchitis; Bronchoalveolar Lavage Fluid; Cromolyn Sodium; | 1991 |
Inhibition of active anaphylaxis in mice and guinea pigs by the new hetrazepinoic PAF antagonist bepafant (WEB 2170).
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Bronchoconstriction; Guinea Pigs; Immunization; Male | 1991 |
Mechanism of the potentiation of neurally-induced bronchoconstriction by gallamine in the guinea-pig.
Topics: Acetylcholine; Anaphylaxis; Animals; Atropine; Bronchi; Captopril; Cholinesterase Inhibitors; Electr | 1990 |
Anaphylactic responses of guinea-pig lung parenchymal strips: antigen concentration dependence and pharmacological modification.
Topics: Anaphylaxis; Animals; Antigens; Chromones; Female; Guinea Pigs; Histamine Release; In Vitro Techniqu | 1986 |
CI-922--a novel, potent antiallergic compound--II. Activity in animal models of allergy.
Topics: Anaphylaxis; Animals; Ascaris; Azoles; Bronchial Spasm; Cromolyn Sodium; Cross Reactions; Dogs; Hist | 1987 |
Experimental renal anaphylaxis: release of histamine and study of its effect on renal perfusion.
Topics: Anaphylaxis; Animals; Cimetidine; Guinea Pigs; Histamine; Histamine Release; Immune Sera; Immunoglob | 1987 |
Passive air-pouch anaphylaxis in rats. II. Pharmacological characterization.
Topics: Adult; Air; Anaphylaxis; Animals; Capillary Permeability; Chromones; Cromolyn Sodium; Dexamethasone; | 1989 |
Inhibition of immunological histamine release from guinea pig lungs and other organs by mepyramine, ketotifen, and picumast in vivo.
Topics: Aminopyridines; Anaphylaxis; Animals; Coumarins; Female; Guinea Pigs; Histamine; Histamine H1 Antago | 1989 |
Nedocromil sodium inhibits IgE- and IgG-related antigen-induced contraction in guinea-pig trachea.
Topics: Airway Resistance; Anaphylaxis; Animals; Benzoquinones; Chromones; Cromolyn Sodium; Flavonols; Guine | 1989 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C | 1989 |
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guin | 1989 |
Airway hyperreactivity follows anaphylactic microshock in anaesthetized guinea-pigs.
Topics: Acetylcholine; Administration, Inhalation; Anaphylaxis; Anesthesia; Animals; Guinea Pigs; Injections | 1989 |
Protective effects of histamine H1 and H2 antagonists, adenosine and hydrocortisone on cardiac anaphylaxis.
Topics: Adenosine; Aminopyridines; Anaphylaxis; Animals; Arrhythmias, Cardiac; Cardiac Output; Cimetidine; G | 1989 |
Failure of a combined anti-histamine and anti-leukotriene treatment to suppress passive anaphylaxis in the guinea-pig.
Topics: Anaphylaxis; Animals; Aspirin; Chromones; Female; Guinea Pigs; Histamine H1 Antagonists; In Vitro Te | 1986 |
The effects of a fish-oil-enriched diet on pulmonary mechanics during anaphylaxis.
Topics: Airway Resistance; Anaphylaxis; Animals; Dietary Fats; Fatty Acids, Unsaturated; Fish Oils; Guinea P | 1985 |
Enhancement of plasma levels of biologically active leukotriene B compounds during anaphylaxis in guinea pigs pretreated by indomethacin or by a fish oil-enriched diet.
Topics: Anaphylaxis; Animals; Cattle; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Dietary F | 1986 |
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs.
Topics: Anaphylaxis; Animals; Atropine; Chromones; Cromolyn Sodium; Guinea Pigs; Indomethacin; Ketotifen; Ma | 1986 |
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic; | 1988 |
Anaphylaxis in guinea pigs induced by ovalbumin aerosol in vivo and in vitro methods.
Topics: Aerosols; Anaphylaxis; Animals; Guinea Pigs; Hemodynamics; Male; Ovalbumin; Pyrilamine; Respiratory | 1987 |
Interactions between granulocytes and platelets with the guinea-pig lung in passive anaphylactic shock. Correlations with PAF-acether-induced lesion.
Topics: Anaphylaxis; Animals; Blood Platelets; Bronchial Spasm; Female; Granulocytes; Guinea Pigs; Lung; Mal | 1987 |
Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis.
Topics: Administration, Oral; Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Immunization; Imm | 1987 |
The effect of inhaled leukotriene D4, histamine, or antigen on central and peripheral airways of guinea pigs: analysis of bronchograms with an interactive image analysis system.
Topics: Anaphylaxis; Animals; Antigens; Benzoquinones; Bronchi; Female; Guinea Pigs; Histamine; Male; Pyrila | 1987 |
Pharmacological control of the in vivo passive anaphylactic shock by the PAF-acether antagonist compound BN 52021.
Topics: Anaphylaxis; Animals; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Plant Extracts; Plate | 1986 |
Pharmacological analysis of the vascular permeability response in the anaphylactic phase of allergic inflammation in rats.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromones; Dexamethasone; Histamine; Indomethacin; Inf | 1985 |