Page last updated: 2024-11-03

pyrilamine and Allodynia

pyrilamine has been researched along with Allodynia in 7 studies

Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
"Histamine and calcitonin gene-related peptide (CGRP) contribute to the pain perception."7.77Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats. ( Ghasri, S; Hamzely, A; Khoshkholgh Sima, B; Mobarakeh, JI; Nezhad, RM; Nunoki, K; Rahimi, AA; Takahashi, K; Torkaman-Boutorabi, A; Yanai, K, 2011)
"Histamine and calcitonin gene-related peptide (CGRP) contribute to the pain perception."3.77Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats. ( Ghasri, S; Hamzely, A; Khoshkholgh Sima, B; Mobarakeh, JI; Nezhad, RM; Nunoki, K; Rahimi, AA; Takahashi, K; Torkaman-Boutorabi, A; Yanai, K, 2011)
"We assessed hyperalgesia, by measuring tail flick latency following tail immersion in water at 49 degrees C, immediately after releasing the tourniquet and then at 30 min intervals for 2 h."1.27Injectable aspirin and mepyramine abolish post-ischaemic hyperalgesia in rats. ( Butkow, N; Gelgor, L; Mitchell, D; Phillips, S, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, H1
Altenbach, RJ1
Carr, TL1
Chandran, P1
Hsieh, GC1
Lewis, LG1
Manelli, AM1
Milicic, I1
Marsh, KC1
Miller, TR1
Strakhova, MI1
Vortherms, TA1
Wakefield, BD1
Wetter, JM1
Witte, DG1
Honore, P1
Esbenshade, TA1
Brioni, JD1
Cowart, MD1
Bernardes, CP1
Menaldo, DL1
Mamede, CC1
Zoccal, KF1
Cintra, AC1
Faccioli, LH1
Stanziola, L1
de Oliveira, F1
Sampaio, SV1
Yu, J1
Tang, YY1
Wang, RR1
Lou, GD1
Hu, TT1
Hou, WW1
Yue, JX1
Ohtsu, H1
Shi, LY1
Zhang, SH1
Chen, Z1
Mobarakeh, JI1
Torkaman-Boutorabi, A1
Rahimi, AA1
Ghasri, S1
Nezhad, RM1
Hamzely, A1
Khoshkholgh Sima, B1
Takahashi, K1
Nunoki, K1
Yanai, K1
Liu, T1
Bai, ZT1
Pang, XY1
Chai, ZF1
Jiang, F1
Ji, YH1
Bennett, G1
Al-Rashed, S1
Hoult, SJR1
Brain, DS1
Gelgor, L1
Phillips, S1
Butkow, N1
Mitchell, D1

Other Studies

7 other studies available for pyrilamine and Allodynia

ArticleYear
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal;

2008
Evaluation of the local inflammatory events induced by BpirMP, a metalloproteinase from Bothrops pirajai venom.
    Molecular immunology, 2015, Volume: 68, Issue:2 Pt B

    Topics: Animals; Bothrops; Cell Degranulation; Cromolyn Sodium; Crotalid Venoms; Cyclooxygenase Inhibitors;

2015
A critical time window for the analgesic effect of central histamine in the partial sciatic ligation model of neuropathic pain.
    Journal of neuroinflammation, 2016, 06-24, Volume: 13, Issue:1

    Topics: Analgesics; Animals; Central Nervous System; Cimetidine; Disease Models, Animal; Drug Administration

2016
Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats.
    Biomedical research (Tokyo, Japan), 2011, Volume: 32, Issue:3

    Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antag

2011
Degranulation of mast cells and histamine release involved in rat pain-related behaviors and edema induced by scorpion Buthus martensi Karch venom.
    European journal of pharmacology, 2007, Dec-01, Volume: 575, Issue:1-3

    Topics: Animals; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Edema; Histamine Antagonist

2007
Nerve growth factor induced hyperalgesia in the rat hind paw is dependent on circulating neutrophils.
    Pain, 1998, Volume: 77, Issue:3

    Topics: Animals; Antibodies; Hindlimb; Histamine H1 Antagonists; Hyperalgesia; Leukotrienes; Lipoxygenase In

1998
Injectable aspirin and mepyramine abolish post-ischaemic hyperalgesia in rats.
    Pain, 1986, Volume: 26, Issue:3

    Topics: Aminopyridines; Animals; Aspirin; Histamine; Hyperalgesia; Hyperesthesia; Ischemia; Male; Prostaglan

1986