Page last updated: 2024-11-03

pyrilamine and Airway Obstruction

pyrilamine has been researched along with Airway Obstruction in 5 studies

Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

ExcerptRelevanceReference
"Inhaled adenosine induces airway obstruction in asthmatic but not healthy subjects, a phenomenon that is also observed in various animal species when they are immunised to a relevant antigen, but which does not occur in naïve animals."3.73Mechanism of adenosine-induced airways obstruction in allergic guinea pigs. ( Boswell-Smith, V; Keir, S; Page, C; Spina, D, 2006)
"The contributions of histamine, cysteinyl leukotrienes (CysLTs) and thromboxane A2 (TXA2) to the asthmatic responses and the magnitudes of blood and lung eosinophilia at acute and chronic stages of our asthmatic model were comparatively determined."3.70Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs. ( Kohno, S; Nabe, T; Tomioka, H; Yamashita, K, 1999)
"Pretreatment with pyrilamine, an antihistamine, suppressed the increase in RL in immature animals, whereas the remaining component of the increase in RL was seen in adult animals."1.30Effect of maturation on allergen-induced airflow obstruction and airway plasma exudation in sensitized guinea pigs. ( Arakawa, H; Lötvall, J; Mochizuki, H; Morikawa, A; Tokuyama, K, 1997)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keir, S1
Boswell-Smith, V1
Spina, D1
Page, C1
Kondratenko, TY1
Zacharova, IV1
Kuzina, NV1
Severin, ES1
Kornilova, ZCh1
Perelman, MI1
Arakawa, H1
Tokuyama, K1
Mochizuki, H1
Morikawa, A1
Lötvall, J1
Yamashita, K1
Nabe, T1
Tomioka, H1
Kohno, S1
Stengel, PW1
Pechous, PA1
Silbaugh, SA1

Other Studies

5 other studies available for pyrilamine and Airway Obstruction

ArticleYear
Mechanism of adenosine-induced airways obstruction in allergic guinea pigs.
    British journal of pharmacology, 2006, Volume: 147, Issue:7

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor

2006
The study of histamine H1- and H2-receptors in human lung cancer.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Adult; Airway Obstruction; Chronic Disease; Cimetidine; Humans; Lung Neoplasms; Midd

1993
Effect of maturation on allergen-induced airflow obstruction and airway plasma exudation in sensitized guinea pigs.
    International archives of allergy and immunology, 1997, Volume: 112, Issue:2

    Topics: Age Factors; Airway Obstruction; Airway Resistance; Allergens; Animals; Asthma; Exudates and Transud

1997
Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs.
    Japanese journal of pharmacology, 1999, Volume: 81, Issue:1

    Topics: Administration, Inhalation; Airway Obstruction; Aluminum Hydroxide; Animals; Antigens; Asthma; Benzo

1999
Mechanism of A23187-induced airway obstruction in the guinea pig.
    Prostaglandins, 1987, Volume: 33, Issue:4

    Topics: Aerosols; Airway Obstruction; Animals; Atropine; Calcimycin; Guinea Pigs; Histamine Release; Lung; M

1987