pyrilamine has been researched along with Age-Related Memory Disorders in 11 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Furthermore, the effects of UW-MD-71 on memory deficits induced by the non-competitive N-methyl-d-aspartate (NMDA) antagonist dizocilpine (DIZ) were tested." | 1.43 | The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats. ( Darras, FH; Decker, M; Khan, N; Nurulain, SM; Saad, A; Sadek, B, 2016) |
| "To investigate the role of histamine in memory deficits induced by MK-801 infusion into the ventral hippocampus in rats." | 1.33 | Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats. ( Chen, Z; Hu, WW; Liu, LY; Ma, L; Wei, EQ; Xu, LS; Yang, LX; Yu, X, 2005) |
| "MK-801 caused spatial memory deficits more potently in histidine-deficient rats than in controls." | 1.31 | Effects of the NMDA antagonist MK-801 on radial maze performance in histidine-deficient rats. ( Fujii, Y; Kamei, C; Nishiga, M; Sugimoto, Y; Taga, C, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (81.82) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, N | 1 |
| Saad, A | 1 |
| Nurulain, SM | 1 |
| Darras, FH | 1 |
| Decker, M | 1 |
| Sadek, B | 1 |
| Xu, LS | 2 |
| Fan, YY | 1 |
| He, P | 1 |
| Zhang, WP | 1 |
| Hu, WW | 2 |
| Chen, Z | 3 |
| Ono, Y | 1 |
| Kataoka, T | 1 |
| Miyake, S | 1 |
| Sasaguri, K | 1 |
| Sato, S | 1 |
| Onozuka, M | 1 |
| Masuoka, T | 2 |
| Kamei, C | 6 |
| Mikami, A | 1 |
| Yang, LX | 1 |
| Yu, X | 1 |
| Ma, L | 1 |
| Liu, LY | 1 |
| Wei, EQ | 1 |
| Yamamoto, Y | 1 |
| Adachi, Y | 1 |
| Fujii, Y | 3 |
| Nakazato, E | 1 |
| Yamamoto, T | 1 |
| Ohno, M | 1 |
| Watanabe, S | 1 |
| Taga, C | 2 |
| Sugimoto, Y | 2 |
| Nishiga, M | 2 |
| Chen, JQ | 1 |
11 other studies available for pyrilamine and Age-Related Memory Disorders
| Article | Year |
|---|---|
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Topics: Animals; Avoidance Learning; Benzothiazoles; Cholinesterase Inhibitors; Disease Models, Animal; Dizo | 2016 |
Ameliorative effects of histamine on spatial memory deficits induced by scopolamine infusion into bilateral dorsal or ventral hippocampus as evaluated by the radial arm maze task.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Hippocampus; Histamine; Histamine H1 Antagoni | 2009 |
Chewing rescues stress-suppressed hippocampal long-term potentiation via activation of histamine H1 receptor.
Topics: Adaptation, Psychological; Animals; Brain; Hippocampus; Histamine H1 Antagonists; Long-Term Potentia | 2009 |
The ameliorating effects of NMDA receptor agonists on histamine H1 antagonist-induced memory and hippocampal theta disruptions are prevented by the H3 receptor agonist in rats.
Topics: Animals; Cycloserine; Excitatory Amino Acid Agonists; Hippocampus; Histamine Agonists; Histamine H1 | 2009 |
Ameliorative effect of a hippocampal metabotropic glutamate- receptor agonist on histamine H1 receptor antagonist-induced memory deficit in rats.
Topics: Aminobutyrates; Animals; Drug Interactions; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Hi | 2010 |
Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats.
Topics: Animals; Cimetidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Histamine; | 2005 |
Ginkgo biloba extract improves spatial memory in rats mainly but not exclusively via a histaminergic mechanism.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Diphenhydramine; Donepezil; Ginkgo biloba; Histamine | 2007 |
Cholinergic and glutamatergic activation reverses working memory failure by hippocampal histamine H1 receptor blockade in rats.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Cimetidine; Cycloserine; Drug Interactions; Gluta | 2000 |
Effects of vasopressin on histamine H(1) receptor antagonist-induced spatial memory deficits in rats.
Topics: Animals; Arginine Vasopressin; Brain; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H | 2001 |
Effect of H1-antagonists on spatial memory deficit evaluated by 8-arm radial maze in rats.
Topics: Animals; Cognition; Dibenzazepines; Diphenhydramine; Histamine H1 Antagonists; Imidazoles; Male; Maz | 2001 |
Effects of the NMDA antagonist MK-801 on radial maze performance in histidine-deficient rats.
Topics: Amino Acids; Animals; Brain; Diet; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Histamine | 2002 |