Page last updated: 2024-11-03

pyrilamine and Active Hyperemia

pyrilamine has been researched along with Active Hyperemia in 7 studies

Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
" Subsequent dose-response studies with other serotonergic and dopaminergic antagonists suggested that dopaminergic receptors are involved in the adaptive response to the irritant."1.28A role for dopamine as an endogenous protective factor in the rat stomach. ( MacNaughton, WK; Wallace, JL, 1989)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pellinger, TK1
Simmons, GH1
Maclean, DA1
Halliwill, JR1
Wong, BJ1
Williams, SJ1
Minson, CT1
Argenbright, LW1
Forbes, PD1
Stewart, GJ1
Clark, KE1
Farley, DB1
Van Orden, DE1
Brody, MJ1
MacNaughton, WK1
Wallace, JL1
Woodward, DF1
Johnson, L1
Spada, C1
Chen, J1
Leon, J1
Charap, A1
Duzman, E1
Shen, CD1

Trials

2 trials available for pyrilamine and Active Hyperemia

ArticleYear
Local histamine H(1-) and H(2)-receptor blockade reduces postexercise skeletal muscle interstitial glucose concentrations in humans.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2010, Volume: 35, Issue:5

    Topics: Adult; Cimetidine; Ethanol; Exercise; Extracellular Space; Female; Glucose; Histamine H1 Antagonists

2010
Efficacy of cimetidine/pyrilamine eyedrops. A dose response study with histamine challenge.
    Ophthalmology, 1986, Volume: 93, Issue:1

    Topics: Adult; Aminopyridines; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug

1986

Other Studies

5 other studies available for pyrilamine and Active Hyperemia

ArticleYear
Minimal role for H1 and H2 histamine receptors in cutaneous thermal hyperemia to local heating in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2006, Volume: 100, Issue:2

    Topics: Adult; Enzyme Inhibitors; Female; Forearm; Histamine H1 Antagonists; Hot Temperature; Humans; Hypere

2006
Quantitation of phototoxic hyperemia and permeability to protein: II. Inhibition by histamine (H1 and H2) receptor antagonists in mouse skin.
    The Journal of investigative dermatology, 1980, Volume: 75, Issue:5

    Topics: Animals; Anthracenes; Blood Circulation; Capillary Permeability; Cimetidine; Female; Hyperemia; Male

1980
Estrogen-induced uterine hyperemia and edema persist during histamine receptor blockade.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 156, Issue:3

    Topics: Animals; Burimamide; Capillary Permeability; Edema; Estradiol; Female; Hyperemia; Pyrilamine; Rats;

1977
A role for dopamine as an endogenous protective factor in the rat stomach.
    Gastroenterology, 1989, Volume: 96, Issue:4

    Topics: Animals; Cyproheptadine; Dopamine; Dopamine Agents; Dopamine Antagonists; Ethanol; Gastric Mucosa; H

1989
Effect of cimetidine and pyrilamine on histamine-induced ocular surface hyperemia.
    Journal of ocular pharmacology, 1986,Summer, Volume: 2, Issue:3

    Topics: Aminopyridines; Animals; Cimetidine; Drug Therapy, Combination; Eye Diseases; Female; Histamine; Hyp

1986